Nisin from Lactococcus lactis, CAS No.1414-45-5

CAS: 1414-45-5 Cat. No.: N432064 Peso molecular: 3354.07 Número EC: 215-807-5 PubChem CID: 614273
Disponible para pedir
GRADE & PURITY 2.5% (balance sodium chloride)
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1g
N432064-1g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

135,90US$

159,90US$
Guardar 24,00 US$ (15.01%)
5g
N432064-5g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

356,90US$

417,90US$
Guardar 61,00 US$ (14.60%)
25g
N432064-25g
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

1.213,90US$

1.417,90US$
Guardar 204,00 US$ (14.39%)
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Why this grade

2.5% (balance sodium chloride) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 23 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Chemical structure: peptide


Application

Nisin is a polycyclic lantibiotic produced by Lactococcus lactis . It is commonly used as a food preservative. It is also used as a selective agent in cell culture for the isolation of gram-negative bacteria, yeast, and molds. Nisin has been used in bioassays to study posttranslational modification. Used to form targeted pores in cell membranes that are mediated by lipid II. Used to study the assembly and stability of nisin-lipid II pore complexes.


Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Specifications

Product Name
Nisin from Lactococcus lactis, CAS No.1414-45-5
Especificaciones y pureza
2.5% (balance sodium chloride)
Mecanismos bioquímicos y fisiológicos
Nisin binds to cell wall precursor lipid components of bacteria and disrupts cell wall production. Nisin alters the cell membrane which results in the leakage of cytoplasmic components and destruction of the proton motive force. Nisin is an antibiotic wi
CAS
1414-45-5
Tipo de molécula
Peptide
Almacenamiento y envío
Concentración
2.5% (balance sodium chloride)
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C
Enviado en
Wet ice

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Hu Yao, Xing Kequan, Li Xiaojing, Sang Shangyuan, McClements David Julian, Chen Long, Long Jie, Jiao Aiquan, Xu Xueming, Wang Jinpeng, Jin Zhengyu, Qiu Chao.  (2023)  Cyclodextrin carboxylate improves the stability and activity of nisin in a wider range of application conditions.  npj Science of Food,  (1): (1-9).  [PMID:37210414] [10.1038/s41538-023-00181-7]
2. Guo Hui, Yang Wei, Lei Bingshuang, Zhao Fengju, Guo Lili, Qian Junqing.  (2023)  Synergistic antimicrobial effect of nisin−octanoic acid nanoemulsions against E. coli and S. aureus.  ARCHIVES OF MICROBIOLOGY,  205  (5): (1-10).  [PMID:37086306] [10.1007/s00203-023-03545-5]
3. Liang Haoyu, Song Zhi-Man, Zhong Zheng, Zhang Dengwei, Yang Wei, Zhou Le, Older Ethan A., Li Jie, Wang Huan, Zeng Zhirui, Li Yong-Xin.  (2023)  Genomic and metabolic analyses reveal antagonistic lanthipeptides in archaea.  Microbiome,  11  (1): (1-12).  [PMID:37060102] [10.1186/s40168-023-01521-1]
4. Mengxia Duan, Jishuai Sun, Shan Yu, Zijian Zhi, Jie Pang, Chunhua Wu.  (2023)  Insights into electrospun pullulan-carboxymethyl chitosan/PEO core-shell nanofibers loaded with nanogels for food antibacterial packaging.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:36709819] [10.1016/j.ijbiomac.2023.123433]
5. Jia Li, Bo-Xiang Wang, De-Hong Cheng, Yue Zhang, Qiang Yao, Xin-bin Ji, Jing Guo, Yan-Hua Lu.  (2022)  An Eco-Friendly Antheraea Pernyi Silk Gland Protein/Sodium Alginate Multiple Network Hydrogel as Potential Drug Release Systems.  Gels,  (1): (4).  [PMID:36661772] [10.3390/gels9010004]
6. Chunhua Wu, Zijian Zhi, Mengxia Duan, Jishuang Sun, Haixin Jiang, Jie Pang.  (2022)  Insights into the formation of carboxymethyl chitosan-nisin nanogels for sustainable antibacterial activity.  FOOD CHEMISTRY,      [PMID:36166921] [10.1016/j.foodchem.2022.134260]
7. Wei Jia, Xixuan Wu, Ruiting Li, Shuxing Liu, Lin Shi.  (2021)  Effect of nisin and potassium sorbate additions on lipids and nutritional quality of Tan sheep meat.  FOOD CHEMISTRY,      [PMID:34256226] [10.1016/j.foodchem.2021.130535]
8. He Yangbo, Li Yongfu, Luo Xingbang, Li Guolin, Duan Zhaoyan, Chen Chaojun.  (2021)  Effects of thermal and nonthermal processing technology on the quality of red sour soup after storage.  Food Science & Nutrition,  (7): (3863-3872).  [PMID:34262743] [10.1002/fsn3.2366]
9. Jinye Zhang, Sihang Li, Wenjing Wang, Jianfei Pei, Jiawei Zhang, Tianli Yue, Wirote Youravong, Zhenyu Li.  (2020)  Bacteriocin assisted food functional membrane for simultaneous exclusion and inactivation of Alicyclobacillus acidoterrestris in apple juice.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2020.118741]
10. Yang Yang, Handong Liu, Min Wu, Jinxia Ma, Peng Lu.  (2020)  Bio-based antimicrobial packaging from sugarcane bagasse nanocellulose/nisin hybrid films.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:32535206] [10.1016/j.ijbiomac.2020.06.081]
11. Chen Zhang, Sheng Guo, Zhao Zhao, Zi-Rao Guo, Rui Ma, Gao-Xue Wang, Bin Zhu.  (2020)  Surface display of spring viremia of carp virus glycoprotein on Lactococcus lactis and its protection efficacy in common carp (Cyprinus carpio L.).  FISH & SHELLFISH IMMUNOLOGY,      [PMID:32534229] [10.1016/j.fsi.2020.06.021]
12. Xuejian Yu, Naiyan Lu, Jiyue Wang, Zhe Chen, Chen Chen, Joe Mac Regenstein, Peng Zhou.  (2020)  Effect of N-terminal modification on the antimicrobial activity of nisin.  FOOD CONTROL,      [PMID:] [10.1016/j.foodcont.2020.107227]
13. Wang Si-Yu, Han Deng-Cheng, Song Chao, Li Meng-Na, Afzal Muhammad Zaheer, Wang Shu-Guang, Sun Xue-Fei.  (2019)  Membrane biofouling retardation by zwitterionic peptide and its impact on the bacterial adhesion.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  26  (16): (16674-16681).  [PMID:30989603] [10.1007/s11356-019-04898-5]
14. Jianming Zhang, Huaxi Yi, Pimin Gong, Kai Lin, Shiwei Chen, Xue Han, Lanwei Zhang.  (2018)  Adsorption of plantaricin Q7 on montmorillonite and application in feedback regulation of plantaricin Q7 synthesis by Lactobacillus plantarum Q7.  ENGINEERING IN LIFE SCIENCES,  19  (1): (57-65).  [PMID:32624956] [10.1002/elsc.201800086]
15. Peng Lu, Mengya Guo, Zhijun Xu, Min Wu.  (2018)  Application of Nanofibrillated Cellulose on BOPP/LDPE Film as Oxygen Barrier and Antimicrobial Coating Based on Cold Plasma Treatment.  Coatings,  (6): (207).  [PMID:] [10.3390/coatings8060207]
16. Zihao Zhang, Lu Mu, Jinlong Li, Haixin Zhao, Hong-Man Hou, Gong-liang Zhang, Hongshun Hao, Jingran Bi.  (2025)  A double cross-linked film based on carboxymethyl chitosan binding with L-cysteine/ oxidized konjac glucomannan with slow-release of nisin for food preservation.  FOOD CHEMISTRY,      [PMID:39827557] [10.1016/j.foodchem.2025.142876]
17. Peng-Hao Zhao, Jun-Wu Cai, Yan Li, Qiao-Hui Li, Meng-Meng Niu, Xiang-Chen Meng, Fei Liu.  (2024)  An insight into structure-activity relationships in subclass IIb bacteriocins: Plantaricin EvF.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39134194] [10.1016/j.ijbiomac.2024.134656]
18. Ren Liu, Kejun Li, Liangyue Fang, Wanru Luo, Shuangfei Wang, Chongxing Huang.  (2024)  Edible freshness-keeping film prepared by Pouteria campechiana pericarp residue and applied to the preservation of duck breast meat.  Food Packaging and Shelf Life,      [PMID:] [10.1016/j.fpsl.2024.101268]
19. Hang Jia, Wenhao Zhang, Mengyao Wang, Yanli Xie, Renyong Zhao, Tianli Yue.  (2025)  A nisin-mediated organic-inorganic hybrid for the inhibition of Alicyclobacillus acidoterrestris in apple juice.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.107638]
20. Xiaotong Wei, Yuanyuan Hu, Chaomin Sun, Shimei Wu.  (2024)  Characterization of a Novel Antimicrobial Peptide Bacipeptin against Foodborne Pathogens.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38429098] [10.1021/acs.jafc.4c00573]
21. Zhang Pei, Yang Huanggen, Ahmad Malik Taj, Zheng Qi, Nie Guochao, Ahmad Ayesha, Raza Muslim, Raza Saleem.  (2025)  Integrating Modified Fe3O4 Nanoparticles and Nisin with T4 Bacteriophage for Enhanced Biofilm Eradication.  CURRENT MICROBIOLOGY,  82  (6): (1-10).  [PMID:40198373] [10.1007/s00284-025-04212-2]
22. Weimin Xing, Wenyan Liu, Bei Yang, Linwang Fan, Yan Zhou, Zhuoyue Wang, Cheng Niu, Jiacheng Li, Yuhong Feng.  (2026)  In situ multi-crosslinked bacterial cellulose with enhanced mechanical and barrier properties for antimicrobial food contact packaging.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41605394] [10.1016/j.ijbiomac.2026.150546]
23. Xiangrui Ren, Li Niu, Liping Zhao, Wenqing Zhao, Qian Lin, Shuangfeng Guo, Yayun Hu, Wenhao Li.  (2026)  Rational design of antibacterial and biodegradable PCL/oxidized cassava starch/Nisin ternary films based on molecular docking.  JOURNAL OF FOOD ENGINEERING,      [PMID:] [10.1016/j.jfoodeng.2026.113043]
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