Oltipraz - ≥98% , CAS No.64224-21-1

CAS: 64224-21-1 Cat. No.: O136690 Peso molecular: 226.34 Número EC: 264-736-6

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Oltipraz - ≥98% CAS No(64224-21-1) by Aladdin Scientific

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Disponible para pedir

GRADE & PURITY ≥98%

Synonyms

BCP16064 | RP 35972;NSC 347901 | BRN 0978110 | DTXSID7021079 | NSC347901 | NSC-347901 | Q7088765 | 4-methyl-5-(pyrazin-2-yl)-3H-1,2-dithiole-3-thione | A13164 | NSC759840 | NSC-759840 | MFCD00868499 | SR-05000001517-1 | AB01275510_02 | C8H6N2S3 | SMR00155

Storage

Conservar a 2-8°C,Protegido de la luz,Cargado con argón

Shipped In

Hielo húmedo

Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Preguntas frecuentes y artículos Citations of This Product Referencias Calculadoras de soluciones Reseñas

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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Conservar a 2-8°C,Protegido de la luz,Cargado con argón Ships Hielo húmedo Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

El oltipraz tiene un efecto inhibidor de la activación de HIF-1α por la insulina en función del tiempo, anulando por completo la inducción de HIF-1α a concentraciones ≥10 μM; el IC50 del oltipraz para la inhibición de HIF-1α es de 10 μM.
El oltipraz es un potente activador de Nrf2 y un potente inductor de las enzimas de desintoxicación de fase II, sobre todo la glutatión-S-transferasa (GST).

Specifications

Sinónimos

BCP16064 | RP 35972;NSC 347901 | BRN 0978110 | DTXSID7021079 | NSC347901 | NSC-347901 | Q7088765 | 4-methyl-5-(pyrazin-2-yl)-3H-1, 2-dithiole-3-thione | A13164 | NSC759840 | NSC-759840 | MFCD00868499 | SR-05000001517-1 | AB01275510_02 | C8H6N2S3 | SMR00155

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

El oltipraz es un activador de Nrf2. El Nrf2 (factor 2 relacionado con el NF-E2) es un factor de transcripción que se une a los elementos de respuesta antioxidante (ARE) y activa estos genes. El oltipraz activa el Nrf2 y, por consiguiente, aumenta la expr

Condiciones de almacenamiento de almacenamiento

Conservar a 2-8°C, Protegido de la luz, Cargado con argón

Enviado en

Hielo húmedo

Nota

Siempre que sea posible, prepare y utilice las soluciones el mismo día. Sin embargo, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.

Pureza

≥98%

Nombres e identificadores

Pubchem Sid	504753641
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504753641
Sonrisas canónicas	CC1=C(SSC1=S)C2=NC=CN=C2
IUPAC Name	4-methyl-5-pyrazin-2-yldithiole-3-thione
InChIKey	CKNAQFVBEHDJQV-UHFFFAOYSA-N
INCHI	1S/C8H6N2S3/c1-5-7(12-13-8(5)11)6-4-9-2-3-10-6/h2-4H,1H3
Isómeros SMILES	CC1=C(SSC1=S)C2=NC=CN=C2
WGK Alemania	3
RTECS	JP1293000
Peso molecular	226.34
Reaxy-Rn	978110
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=978110&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Clase Diazines
    - Subclass Pyrazines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Clase	Diazines
Subclass	Pyrazines
Intermediate Tree Nodes	Not available
Direct Parent	Pyrazines
Alternative Parents	1,2-dithiole-3-thiones Heteroaromatic compounds Azacyclic compounds Organosulfur compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	1,2-dithiole-3-thione - Pyrazine - Heteroaromatic compound - Dithiole - 1,2-dithiole - Azacycle - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organosulfur compound - Organonitrogen compound - Aromatic heteromonocyclic compound
Descripción	This compound belongs to the class of organic compounds known as pyrazines. These are compounds containing a pyrazine ring, which is a six-member aromatic heterocycle, that consists of two nitrogen atoms (at positions 1 and 4) and four carbon atoms.
External Descriptors	pyrazines - 1,2-dithiole
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

PTPN11 Tchem Protein-tyrosine phosphatase 2C (2297 Activities)

Discover Target: PTPN11

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)

Discover Target: CYP1A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NQO1 Tchem Quinone reductase 1 (1746 Activities)

Discover Target: NQO1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Fecha	Articulo
I2226008	Certificate of Analysis	Apr 03, 2026	O136690
I2226009	Certificate of Analysis	Apr 03, 2026	O136690
G23181123	Certificate of Analysis	May 09, 2025	O136690
G23181126	Certificate of Analysis	May 09, 2025	O136690
G23181145	Certificate of Analysis	May 09, 2025	O136690
G23181148	Certificate of Analysis	May 09, 2025	O136690
G23181149	Certificate of Analysis	May 09, 2025	O136690
G23181151	Certificate of Analysis	May 09, 2025	O136690
G23181159	Certificate of Analysis	May 09, 2025	O136690
G23181160	Certificate of Analysis	May 09, 2025	O136690
F1702008	Certificate of Analysis	Oct 15, 2024	O136690
I2226010	Certificate of Analysis	Jul 11, 2022	O136690

Solubilidad	Soluble in methanol, and DMSO ( >20 mg/ml)., Soluble in methanol, and DMSO ( >20 mg/ml).
Sensibilidad	light & heat & air sensitive
Índice de refracción	1.76
Punto de fusión (°C)	165-166°C
Peso molecular	226.300 g/mol
XLogP3	1.100
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	225.969 Da
Monoisotopic Mass	225.969 Da
Topological Polar Surface Area	108.000 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	262.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Oltipraz - ≥98% , CAS No.64224-21-1

Why this grade

Storage & shipping

Quality documents

Literature proof

Descripción general

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

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Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reseñas de cliente

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