Recombinant ERBB2/HER2 Antibody

CAS: 180288-69-1 Cat. No.: Ab304395 Peso molecular: 145531.50 Número EC: 695-702-2

GRADE & PURITY Validated, PBS Only, ≥95%, ~21mg/ml(in buffer，pH6.0)

Isotype

Human IgG1

Specifications

Product Name

Recombinant ERBB2/HER2 Antibody

Especificaciones y pureza

Validated, PBS Only, ≥95%, ~21mg/ml(in buffer，pH6.0)

Grado

PBS Only, Validated

Concentración

~21mg/ml(in buffer，pH6.0)

CAS

180288-69-1

Almacenamiento y envío

Condiciones de almacenamiento de almacenamiento

Protected from light,Store at -20°C

Enviado en

Ice chest + Ice pads

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Clase Purine nucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Clase: Purine nucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine nucleosides
• Alternative Parents: Glycosylamines 6-oxopurines Pentoses Hypoxanthines Pyrimidones Aminopyrimidines and derivatives Aminoimidazoles N-substituted imidazoles Vinylogous amides Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Hydrocarbon derivatives Organic oxides Organopnictogen compounds Primary alcohols Primary amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine nucleoside - Glycosyl compound - N-glycosyl compound - 6-oxopurine - Pentose monosaccharide - Hypoxanthine - Purinone - Imidazopyrimidine - Purine - Aminopyrimidine - Pyrimidone - Aminoimidazole - N-substituted imidazole - Monosaccharide - Pyrimidine - Azole - Tetrahydrofuran - Vinylogous amide - Imidazole - Heteroaromatic compound - Secondary alcohol - Oxacycle - Azacycle - Organoheterocyclic compound - Primary amine - Amine - Alcohol - Organic nitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary alcohol - Organooxygen compound - Organonitrogen compound - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ERBB2 Tclin Receptor tyrosine-protein kinase erbB-2 (0 Activities)

Discover Target: ERBB2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Referencias

1. Li Jinbo, Yu Jiang, Song Jia, Zhang Yingxi, Li Ning, Wang Zhaomeng, Qin Meng, Zhao Mingming, Zhang Baoyue, Huang Ruiping, Zhou Shuang, Liu Yubo, He Zhonggui, Liu Hongzhuo, Dan Liu, Wang Yongjun.  (2025)  Galloylated liposomes enable targeted drug delivery by overcoming protein corona shielding.  Nature Communications,  16  (1): (1-15).  [PMID:40854890] [10.1038/s41467-025-63198-4]

2. Dongmei Li, Chaofan Weng, Chaoyi Chen, Kan Li, Qiang Lin, Yi Ruan, Yi Ruan, Jingjing Zhang, Shuqian Wang, Jia Yao, Jia Yao.  (2022)  Optical biosensor based on weak value amplification for the high sensitivity detection of Pertuzumab in combination with Trastuzumab binding to the extracellular domain of HER2.  OPTICS EXPRESS,  30  (20): (36839-36848).  [PMID:36258605] [10.1364/OE.472012]