GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.Fc tag?Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture.PBS Only?PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers.≥90%(SDS-PAGE)
Expression System
HEK293
Accession #
Q6PE46
Protein Tag
C-hFc
Expression system
HEK293
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.
Animal Free,Carrier Free,Bioactive,ActiBioPure™,Fc tag,PBS Only,≥90%(SDS-PAGE) ActiBioPure™,Animal Free,Bioactive,Carrier Free,Fc tag,PBS Only for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C,Avoid repeated freezing and thawing Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Protein Function: BCMA, B cell maturation antigen, is a member of the TNF receptor superfamily. It has been designated TNFRSF17. BCMA is a type III membrane protein containing one extracellular cysteine rich domain. Within the TNFRSF, it shares the highest homology with TACI. BCMA and TACI have both been shown to bind to APRIL and BAFF, members of the TNF ligand superfamily. BCMA expression has been found in immune organs and mature B cell lines. Although some expression has been observed at the cell surface, BCMA appears to be localized to the Golgi compartment. The binding of BCMA to APRIL or BAFF has been shown to stimulate IgM production in peripheral blood B cells and increase the survival of cultured B cells. This data suggests that BCMA may play an important role in B cell development, function and regulation. Human BCMA is a 184 amino acid (aa) protein consisting of a 54 aa extracellular domain, a 23 aa transmembrane domain, and a 107 aa intracellular domain. Mouse and human BCMA share 62% amino acid identity.
Specifications
Product Name
Recombinant Human BCMA/TNFRSF17 Protein
Sinónimos
B cell maturation antigen | B-cell maturation protein | BCMA | BCMAtumor necrosis factor receptor superfamily member 17 | BCMB-cell maturation factor | CD269 antigen | CD269 | TNFRSF13A | TNFRSF17 | tumor necrosis factor receptor superfamily, member 17,
Grado
ActiBioPure™, Animal Free, Bioactive, Carrier Free, Fc tag, PBS Only
Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.
34.0-44.3 kDa, under reducing conditions; 57.0-90.2 kDa, under non-reducing conditions
Tipo de molécula
Protein
Almacenamiento y envío
Reconstitución
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20°C for 1 year. Avoid freeze / thaw cycle.
Imágenes
Recombinant Human BCMA/TNFRSF17 Protein (rp169554) - ELISA Immobilized Recombinant Human BCMA/TNFRSF17 Protein (rp169554) at 0.5 μg/mL can bind Belantamab (anti-TNFRSF17) (Ab170526) with the EC50 of 22.0 ng/mL.
Recombinant Human BCMA/TNFRSF17 Protein (rp169554) - SDS-PAGE 3 μg/lane of Recombinant Human BCMA/TNFRSF17 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 34.0-44.3 kDa under reducing conditions and 57.0-90.2 kDa under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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