GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Bioactive?Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure.ActiBioPure™?ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required.≥95%(SDS-PAGE)See COA
Accession #
Q08722
Protein Tag
No tag
Expression system
CHO
Endotoxin Concentration
<1.0 EU/μg
Bioactivity
Immobilized Recombinant Human SIRP alpha/CD172a protein (rp183642) at 2.0 μg/mL can bind Recombinant Human CD47 protein (rp169585) with the EC50 of 308.6 ng/mL. Immobilized Recombinant Human CD47 protein (rp169585) at 1.0 μg/mL can bind Ligufalimab (anti-CD47) (Ab191922) with the EC50 of 62.0 ng/mL.
Animal Free, Carrier Free, Bioactive, ActiBioPure™, ≥95%(SDS-PAGE), See COA
Mecanismos bioquímicos y fisiológicos
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in
Bioactividad
Immobilized Recombinant Human SIRP alpha/CD172a protein (rp183642) at 2.0 μg/mL can bind Recombinant Human CD47 protein (rp169585) with the EC50 of 308.6 ng/mL. Immobilized Recombinant Human CD47 protein (rp169585) at 1.0 μg/mL can bind Ligufalimab (anti-CD47) (Ab191922) with the EC50 of 62.0 ng/mL.
32.1-40.9 kDa, under reducing conditions; 46.4-63.5 kDa, under non-reducing conditions.
Tipo de molécula
Protein
Almacenamiento y envío
Concentración
See COA
Condiciones de almacenamiento de almacenamiento
Store at -20°C,Avoid repeated freezing and thawing
Enviado en
Ice chest + Ice pads
Estabilidad y almacenamiento
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
Imágenes
Recombinant Human CD47 protein (rp169585) - Binding Activity Immobilized Recombinant Human SIRP alpha/CD172a protein (rp183642) at 2.0 μg/mL can bind Recombinant Human CD47 protein (rp169585) with the EC₅₀ of 308.6 ng/mL.
Recombinant Human CD47 protein (rp169585) - ELISA Immobilized Recombinant Human CD47 protein (rp169585) at 1.0 μg/mL can bind Ligufalimab (anti-CD47) (Ab191922) with the EC₅₀ of 62.0 ng/mL.
Recombinant Human CD47 Protein (rp169585) - SDS-PAGE 3 μg/lane of Recombinant Human CD47 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 32.1-40.9 kDa under reducing conditions and 46.4-63.5 kDa under non-reducing conditions.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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