Roxithromycin - Moligand™, 10mM in DMSO , Agonist of motilin receptor, CAS No.80214-83-1, Agonist of motilin receptor

CAS: 80214-83-1 Cat. No.: R409235 Peso molecular: 837.05 Número EC: 617-007-5 PubChem CID: 6915744
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
Roxl-150 | (9E)​-9-​[O-​[(2-​methoxyethoxy)​methyl]​oxime]-erythromycin
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
R409235-1ml
1

135,90US$

158,90US$
Guardar 23,00 US$ (14.47%)
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Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 38 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Roxithromycin (Roxl-150) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
Roxl-150 | (9E)​-9-​[O-​[(2-​methoxyethoxy)​methyl]​oxime]-erythromycin
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Roxithromycin (Roxl-150) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
AGONIST
Mecanismo de acción
Agonist of motilin receptor
Nombres e identificadores
Isómeros SMILES CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OCOCCOC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
WGK Alemania 3
RTECS KF4990000
PubChem CID 6915744
Peso molecular 837.05

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
MLNR Tchem Motilin receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Punto de inflamación (°F)>110℃(230°F)
Punto de inflamación (°C)>110℃(230°F)
Punto de fusión (°C)111-118°C
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Jun Yao.  (2023)  A multiple signal amplification photoelectrochemical biosensor based on biotin-avidin system for kanamycin sensing in fish and milk via synergism of g-C3N4 and Ru@SiO2.  ANALYTICA CHIMICA ACTA,      [PMID:38220276] [10.1016/j.aca.2023.342141]
2. Xiaoyu Zhang, Peiran Meng, Wei Wang, Xiwen Li, Zuan Yang, Shaokai Du, Yue Sun.  (2023)  Simultaneous Electrochemical Determination of Erythromycin and Hemoglobin by Flexible Carbon Cloth Modified with ZnO Nanorod Arrays and Au Nanoparticles by Differential Pulse Voltammetry (DPV).  ANALYTICAL LETTERS,      [PMID:] [10.1080/00032719.2023.2292664]
3. Qing Fang, Qin Liu, Zongli Xie, Matthew R. Hill, Kaisong Zhang.  (2023)  Ultra-thin PTMSP nanocomposite membranes incorporated with functionalized MoS2 nanosheets for pharmaceutical concentration and solvent recovery.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.125296]
4. Jutao Hu, Xiaoyu Su, Lei Yuan, Kaiyi Zheng, Xiaobo Zou, Zongbao Sun, Xuechao Xu, Wen Zhang.  (2023)  Competitive immunoassay using enzyme-regulated Fe3O4@COF/Fe3+ fluorescence probe for natural chloramphenicol detection.  ANALYTICA CHIMICA ACTA,      [PMID:37604605] [10.1016/j.aca.2023.341680]
5. Zhiwen Li, Zhilin Zhou, Jianghua Wang, Tingxian Tao, Yingqiang Fu.  (2023)  Aggregation-induced emission enhancement N, S-CQDs for selective detection of CIP in the environment.  NANOTECHNOLOGY,  34  (39): (395503).  [PMID:37343538] [10.1088/1361-6528/ace05a]
6. Weifu Geng, Yan Feng, Yu Chen, Xin Zhang, Haoyi Zhang, Fanfan Yang, Xiuzhong Wang.  (2023)  Interactions of Amino Group Functionalized Tetraphenylvinyl and DNA: A Label-Free “On-Off-On” Fluorescent Aptamer Sensor toward Ampicillin.  Biosensors-Basel,  13  (5): (504).  [PMID:37232865] [10.3390/bios13050504]
7. Shuying Mao, Wei Jin, Sisi Fu, Keanqi Liu, Feng Xu, Linlin Wu, Yexin Xu, Huizhu Yang, Huafang Liu, Guangji Wang, Yan Liang.  (2023)  Strategies for mapping protein hydrolysate profiles and pharmacokinetics based on non-targeted proteomics combining skyline-aided quantitative techniques.  ANALYTICA CHIMICA ACTA,      [PMID:37230566] [10.1016/j.aca.2023.341272]
8. Junyang Pan, Dan Hua, Yiping Hong, Xi Cheng, Fangsong Guo, Kok Bing Tan, Ziqi Zhong, Guowu Zhan.  (2023)  Design of hybrid g-C3N4/GO/MCE photocatalytic membranes with enhanced separation performance under visible-light irradiation.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.143164]
9. Dan Liu, Jiahui Ji, Xinran Guo, Sanhu Gou, Xinyue Chen.  (2023)  Syringe Paper-Based Analytical Device for Thiamazole Detection by Hedysarum Polysaccharides-Mediated Silver Nanoparticles.  Micromachines,  14  (2): (350).  [PMID:36838050] [10.3390/mi14020350]
10. Yu Wang, Yunxiang He, Qin Wang, Xiaoling Wang, Blaise L. Tardy, Joseph J. Richardson, Orlando J. Rojas, Junling Guo.  (2022)  Microporous membranes for ultrafast and energy-efficient removal of antibiotics through polyphenol-mediated nanointerfaces.  Matter,      [PMID:] [10.1016/j.matt.2022.09.021]
11. Zheng Jiahong, Yang Yamei, Cheng Kangkang, Ma Junyu, Yu Pengfei.  (2022)  Mesoporous silica nanoparticles encapsulated carbon quantum dots for detection of tetracycline.  JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS,  33  (21): (17036-17047).  [PMID:] [10.1007/s10854-022-08581-3]
12. Lishan Zhang, Zujie Yao, Huamei Tang, Qingli Song, Huanhuan Song, Jindong Yao, Zhen Li, Xiaofang Xie, Yuexu Lin, Xiangmin Lin.  (2022)  The Lysine Acetylation Modification in the Porin Aha1 of Aeromonas hydrophila Regulates the Uptake of Multidrug Antibiotics.  MOLECULAR & CELLULAR PROTEOMICS,  21  (9):   [PMID:35605723] [10.1016/j.mcpro.2022.100248]
13. Chengan Guo, Zhaoyin Diao, Jianli Liu, Baokun Yang, Jian Zhang.  (2022)  Quantification and evaluation of ion transmission efficiency in two-stage vacuum chamber miniature mass spectrometer.  JOURNAL OF MASS SPECTROMETRY,  57  (3): (e4816).  [PMID:35229406] [10.1002/jms.4816]
14. Ou Panpan, Wu Jiawen, Lin Yu, Tan Xuecai, Wu Yeyu, Chen Zhifan, Wei Fucun, Huang Kejing.  (2022)  Flexible photoelectrochemical sensor for highly sensitive chloramphenicol detection based on M-TiO2-CdTe QDs/CdS QDs composite.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  414  (6): (2065-2078).  [PMID:34984509] [10.1007/s00216-021-03840-4]
15. Yu Wang, Jin-Yi Yang, Ying He, Lu Li, Jian-Xin Huang, Yuan-Xin Tian, Hong Wang, Zhen-Lin Xu, Yu-Dong Shen.  (2021)  Development of Time-Resolved Fluorescence Immunochromatographic Assays for Simultaneously Detecting Tylosin and Tilmicosin in Milk in Group-Screening Manner.  Foods,  10  (8): (1838).  [PMID:34441616] [10.3390/foods10081838]
16. Huiling Zhang, Xiansheng Zhang, Lei Liu, Xiaoyu Pang, Langfei Yang, Bingjie Xu, Jindan Wu, Dongming Qi.  (2021)  Synergistic bactericidal nanofibers with photothermal controlled release of antibiotics triggered by near infrared.  MATERIALS LETTERS,      [PMID:] [10.1016/j.matlet.2021.130423]
17. Zhou Chen, Yanzeng Li, Yanyan Peng, Chengsong Ye, Shenghua Zhang.  (2020)  Effects of antibiotics on hydrolase activity and structure of microbial community during aerobic co-composting of food waste with sewage sludge.  BIORESOURCE TECHNOLOGY,      [PMID:33310386] [10.1016/j.biortech.2020.124506]
18. Ziming Zhao, Yanzhu Guo, Tao Zhang, Jiliang Ma, Haiming Li, Jinghui Zhou, Zhiwei Wang, Runcang Sun.  (2020)  Preparation of carbon dots from waste cellulose diacetate as a sensor for tetracycline detection and fluorescence ink.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:32891644] [10.1016/j.ijbiomac.2020.08.243]
19. Yunlei Zhou, Yue Wang, Shurong Li, Xi Fang, Huanshun Yin, Po Wang, Shiyun Ai.  (2020)  A novel photoelectrochemical immunosensor for N1-methyladenine detection based on BiVO4/g-C3N4 heterojunction with signal amplification of TiO2@NH2-MIL-125(Ti).  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.128310]
20. Nana Xue, Liyi Wang, Wenfeng Li, Shanshan Wang, Xiangliang Pan, Daoyong Zhang.  (2020)  Increased inheritance of structure and function of bacterial communities and pathogen propagation in plastisphere along a river with increasing antibiotics pollution gradient.  ENVIRONMENTAL POLLUTION,      [PMID:32505934] [10.1016/j.envpol.2020.114641]
21. Yueran Zhu, Yunguang Lu, Longyan Shi, Yaling Yang.  (2019)  β-Cyclodextrin functionalized N,Zn codoped carbon dots for specific fluorescence detection of fluoroquinolones in milk samples.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2019.104517]
22. Guo Feng, Zhu Zihan, Zheng Zhangqin, Jin Ying, Di Xiaoxuan, Xu Zhonghao, Guan Hongwei.  (2019)  Facile synthesis of highly efficient fluorescent carbon dots for tetracycline detection.  ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH,  27  (4): (4520-4527).  [PMID:31768961] [10.1007/s11356-019-06779-3]
23. Baoyi Cai, Tian Zhong, Peizhou Chen, Jia Fu, Yuanbao Jin, Yinglei Liu, Ran Huang, Lianjiang Tan.  (2018)  Preparation, characterization and in vitro release study of drug-loaded sodium carboxy-methylcellulose/chitosan composite sponge.  PLoS One,  13  (10): (e0206275).  [PMID:30346976] [10.1371/journal.pone.0206275]
24. Chan-Yuan YAO, Jin-Yi YANG, Zhen-Lin XU, Hong WANG, Hong-Tao LEI, Yuan-Ming SUN, Yuan-Xin TIAN, Yu-Dong SHEN.  (2018)  Indirect Competitive Enzyme-Linked Immunosorbent Assay for Detection of Tylosin in Milk and Water Samples.  CHINESE JOURNAL OF ANALYTICAL CHEMISTRY,      [PMID:] [10.1016/S1872-2040(18)61106-5]
25. Li'na Qiao, Sihua Qian, Yuhui Wang, Shifeng Yan, Hengwei Lin.  (2018)  Carbon-Dots-Based Lab-On-a-Nanoparticle Approach for the Detection and Differentiation of Antibiotics.  CHEMISTRY-A EUROPEAN JOURNAL,  24  (18): (4703-4709).  [PMID:29369443] [10.1002/chem.201706056]
26. Cheng Lin, Jiarun Mao, Yihui Chen, Chunyan Hou, Xiaoqiang Qiao, Ningkun Wu, Tingting Wang.  (2025)  A halloysite nanotubes-based hybrid fluorous monolith as the mixed-mode sorbent for hydrophilic and hydrophobic interactions and its application for analysis of antibiotics from milk powder and milk samples.  FOOD CHEMISTRY,      [PMID:39986074] [10.1016/j.foodchem.2025.143440]
27. Yaowei Zhu, Ruijie Tang, Jun Zhao, Changlong Jiang, Lingfei Li, Bianhua Liu.  (2025)  Design and application of metal-organic framework based chemo-fluorescent sensor for selective sensing of the full spectrum of tetracyclines in complex samples.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160281]
28. Yin-Xia Sun, Xue Bai, Ai-Ping Luo, Yu Sun, Zhe-Peng Deng, Wan-Hong Sun, Wen-Yu Han.  (2025)  Ratiometric fluorescent sensor CQDx@Co/Mn-MOF for rapid and sensitive detection of quinolone antibiotics.  TALANTA,      [PMID:40179685] [10.1016/j.talanta.2025.128034]
29. Ruijie Tang, Lingfei Li, Yaowei Zhu, Minghui Zhan, Jun Zhao, Changlong Jiang, Bianhua Liu.  (2025)  Ratiometric fluorescent sensor for sensitive visualization of full-spectrum fluoroquinolone antibiotic residues in the environment.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.113260]
30. Zixuan Zhao, Bin Luo, Tao Cao, Tongtong Bai, Yifan Sun, Hengrui Liu, Li Zhang, Jun Xie, Jun Wang, Huakang Li, Zichen Duan, Zixuan Gao, Xiaojuan Wang, Jie Gu, Xun Qian, James M. Tiedje.  (2025)  Livestock manure-based organic fertilization facilitates the transmission of antibiotic resistance genes across the soil-onion continuum: A significant contribution from root exudates.  SOIL BIOLOGY & BIOCHEMISTRY,      [PMID:] [10.1016/j.soilbio.2025.109910]
31. Linqian Hou, Qiulan Li, Jitao Li, Dezhi Yang, Yaling Yang.  (2025)  Cu,Fe,B/Cur-CDs with peroxidase- and ascorbic acid oxidase-like catalytic activity for dual-signal fluorescence sensing of metronidazole.  FOOD CHEMISTRY,      [PMID:40774207] [10.1016/j.foodchem.2025.145757]
32. Jiahong Zheng, Xiudan Shi, Pengzhan Li, Zhiguo Zhao, Guangqiang Ding.  (2025)  Preparation of a Cs4PbBr6 NCs@PCDs ratiometric fluorescent probe and detection of amoxicillin.  NEW JOURNAL OF CHEMISTRY,      [PMID:] [10.1039/D5NJ02499D]
33. Xiu-Yan Li, Yu-Ting Luo, Yan-Hong Wang, Zhi-Xin Yang, Yu-Zhou Shang, Qing-Xia Guan.  (2023)  Anti-inflammatory effect and antihepatoma mechanism of carrimycin.  WORLD JOURNAL OF GASTROENTEROLOGY,      [PMID:37122599] [10.3748/wjg.v29.i14.2134]
34. Peng Zhang, Guanghua Lu, Yu Sun, Zhenhua Yan, Tianjian Dang, Jianchao Liu.  (2021)  Metagenomic analysis explores the interaction of aged microplastics and roxithromycin on gut microbiota and antibiotic resistance genes of Carassius auratus.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:34802820] [10.1016/j.jhazmat.2021.127773]
35. Suozhu Wu, Yiqin Zhang, Xuedong Jia, Hao Wu, Jie Mao, Meijun Huo, Hongyuan Guo.  (2025)  Rapid and sensitive detection of chloramphenicol using polyaniline nanorods/reduced graphene oxide-based molecularly imprinted electrochemical sensor.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.112687]
36. Rui Qiu, Xiaolan Lin, Canyan Yang, Xian Chen.  (2025)  CRISPR-enhanced fluorescent signal amplification for ultra-sensitive detection of vancomycin.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.116098]
37. Qihong Cai, Xiaodan Zheng, Sujun Fang, Qifeng Zou, Hang Zhu, Zhima Yangcuo, Yajuan Zhang, Yong Lin, Chunyan Lian, Shiqi Zhang.  (2026)  High sensitive and simultaneous determination of chlortetracycline hydrochloride and tetracycline hydrochloride residues in water using zero-crossing first derivative synchronous fluorescence spectrometry.  PROCESS SAFETY AND ENVIRONMENTAL PROTECTION,      [PMID:] [10.1016/j.psep.2026.108431]
38. Jiawei Bian, Shixin Cai, Xin Chen, Xiaoli Wang, Yuting Zhang, Nandi Zhou.  (2026)  A smartphone-integrated portable fluorescent biosensor for on-site detection of antibiotics.  ANALYTICA CHIMICA ACTA,      [PMID:] [10.1016/j.aca.2026.345564]
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