Salicin - Moligand™, 10mM in DMSO , Agonist of TAS2R16, CAS No.138-52-3, Agonist of TAS2R16

CAS: 138-52-3 Cat. No.: S408989 Peso molecular: 286.28 Beilstein Registry Number: 89593 Número EC: 205-331-6 PubChem CID: 439503

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

Salicoside,Salicine | β-D-Glucopyranoside, 2-(hydroxymethyl)phenyl

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Information

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selectiveCOX-1andCOX-2inhibitor.
In vitro

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. Salicin is a prodrug which is gradually transported to the lower part of the intestine, hydrolyzed to saligenin by intestinal bacteria, and converted to salicylic acid after absorption. It thus produces an antipyretic action without causing gastric injury.

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥98%

Specifications

Sinónimos

Salicoside, Salicine | β-D-Glucopyranoside, 2-(hydroxymethyl)phenyl

Especificaciones y pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Salicin (Salicoside, Salicine) is a phenol β-glycosid produced from willow bark that shows anti-inflammatory effects. It is a natural, non-selective COX-1 and COX-2 inhibitor.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

AGONIST

Mecanismo de acción

Agonist of TAS2R16

Nombres e identificadores

• Isómeros SMILES: C1=CC=C(C(=C1)CO)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O
• WGK Alemania: 3
• RTECS: LZ5901700
• CAS alternativo: 138-52-3
• PubChem CID: 439503
• Número NSC: 758201
• Términos de entrada MeSH: salicin;salicyl alcohol glucoside
• Peso molecular: 286.28
• Beilstein: 89593
• Reaxy-Rn: 89593

Objetivos asociados (humanos)

TAS2R16 Tchem Taste receptor type 2 member 16 (0 Activities)

Discover Target: TAS2R16

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 41 mg/mL (197.79 mM); Ethanol: 41 mg/mL (197.79 mM); Water: Insoluble
• Rotación específica [α]: -62 ° (C=3, H2O)
• Punto de fusión (°C): 199-202°C

Referencias

1. Lei Chen, Ning Li, Min-Hua Zong.  (2011)  A glucose-tolerant β-glucosidase from Prunus domestica seeds: Purification and characterization.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2011.10.023]

2. Zhenyue Wang, Faidah Arina Nur, Jingyi Ma, Jianguo Wang, Chuanwang Cao.  (2019)  Effects of poplar secondary metabolites on performance and detoxification enzyme activity of Lymantria dispar.  COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY,      [PMID:31401083] [10.1016/j.cbpc.2019.108587]

3. Xinqi Gao, Yafang Lei, Teng Sun, Yuanze Ma, Hao Guan, Li Yan.  (2025)  Evaluation of Anti-Fungal Activities of Environmentally Friendly Wood Preservative from Thermal-Induced Lignified Twigs.  Forests,  16  (1): (119).  [PMID:] [10.3390/f16010119]

4. Shangguang Du, Hao Wan, Jun Luo, Xiaohua Duan, Zhengrong Zou.  (2024)  Metabolic profiling of Citrus maxima L. seedlings in response to cadmium stress using UPLC-QTOF-MS.  PLANT PHYSIOLOGY AND BIOCHEMISTRY,      [PMID:38996714] [10.1016/j.plaphy.2024.108920]

5. Mingzhen Zhang, Cong Liu, Yan Zhang, Zhangyaoyu Yuan, Shi Chen, Huihui Zhang, Xianju Huang, Lvyi Chen, Zhinan Mei, Yuebin Ge.  (2025)  Bioactive Components, Untargeted Metabolomics and Bioinformatics of Chaenomeles speciosa Fruit on Uric Acid-Lowering Activity Assessment.  Foods,  15  (1): (20).  [PMID:41517086] [10.3390/foods15010020]