Sodium bis(trimethylsilyl)amide - ≥95% , CAS No.1070-89-9

CAS: 1070-89-9 Cat. No.: S106743 Peso molecular: 183.37 Beilstein Registry Number: 3629917 Número EC: 213-983-8 PubChem CID: 2724254

GRADE & PURITY ≥95%

Synonyms

Hexamethyldisilazane sodium salt | Sodium Hexamethyldisilazide | NaHMDS | N-Sodiohexamethyldisilazane

Storage

Argon charged,Room temperature

Shipped In

Normal

Descripción general

Product Describtion:

Significantly accelerated the polymerization of pheneylacetylene in conjunction with rhodium (I) catalysis

Product Application:

Sodium bis(trimethylsilyl)amide is used as a base in organic synthesis as well as to deprotonate other compounds containing weakly acidic O-H, S-H, and N-H bonds. It is used to prepare amines by reacting with alkyl halides. It finds application in certain organic reactions viz. generation of carbenes by dehydrohalogenation of halocarbons and Wittig reagents by deprotonation of phosphonium salts. It accelerates the polymerization of pheneylacetylene in conjunction with rhodium(I) catalysis. Furthermore, it is used for the preparation of lanthanide complexes.

Specifications

Sinónimos

Hexamethyldisilazane sodium salt | Sodium Hexamethyldisilazide | NaHMDS | N-Sodiohexamethyldisilazane

Especificaciones y pureza

≥95%

Condiciones de almacenamiento de almacenamiento

Argon charged, Room temperature

Enviado en

Normal

Pureza

≥95%

Nombres e identificadores

• Pubchem Sid: 504760870
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504760870
• Sonrisas canónicas: C[Si](C)(C)[N-][Si](C)(C)C.[Na+]
• IUPAC Name: sodium;bis(trimethylsilyl)azanide
• InChIKey: WRIKHQLVHPKCJU-UHFFFAOYSA-N
• INCHI: 1S/C6H18NSi2.Na/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
• Isómeros SMILES: C[Si](C)(C)[N-][Si](C)(C)C.[Na+]
• WGK Alemania: 3
• PubChem CID: 2724254
• Número ONU: 3263
• Grupo de embalaje: II
• Peso molecular: 183.37
• Beilstein: 3629917
• Reaxy-Rn: 3629917

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organometallic compounds
    • Clase Organometalloid compounds
      • Subclass Organosilicon compounds
        • Level5 Organoheterosilanes
          • Level6 Trialkylheterosilanes

• Kingdom: Organic compounds
• Superclass: Organometallic compounds
• Clase: Organometalloid compounds
• Subclass: Organosilicon compounds
• Intermediate Tree Nodes: Organoheterosilanes
• Direct Parent: Trialkylheterosilanes
• Alternative Parents: Organic metalloid salts N-silyl compounds Organic sodium salts Organic nitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Trialkylheterosilane - N-silyl compound - Organic alkali metal salt - Organic metalloid salt - Organic nitrogen compound - Hydrocarbon derivative - Organic sodium salt - Organic salt - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as trialkylheterosilanes. These are organoheterosilanes, bearing a silicon atom linked to three alkyl groups and one heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in hexane, toluene, ether,terahydrofuran, benzene and toluene.
• Sensibilidad: Hygroscopic；Air sensitive
• Punto de inflamación (°F): 1 °F
• Punto de inflamación (°C): -17 °C
• Punto de fusión (°C): 171-175°C
• Peso molecular: 183.370 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 183.088 Da
• Monoisotopic Mass: 183.088 Da
• Topological Polar Surface Area: 1.000 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 80.900
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Xinyan Yu, Yong Wang, Yutong Dong, Ning Zhao, Lifeng Zhang, Sunting Xuan, Zhengbiao Zhang.  (2023)  Efficient Synthesis of N-Methyl Polypeptides by Organic Acid Promoted Controlled Ring-Opening Polymerization of N-Methyl-α-Amino Acids N-Carboxyanhydrides.  MACROMOLECULES,      [PMID:] [10.1021/acs.macromol.3c01102]