Sodium iodoacetate - ≥98% , CAS No.305-53-3

CAS: 305-53-3 Cat. No.: S104897 Peso molecular: 207.93 Beilstein Registry Number: 4009322 Número EC: 206-165-7

GRADE & PURITY ≥98%

Synonyms

EINECS 206-165-7 | E75848 | Iodoacetic acid sodium salt | MFCD00002686 | J-200341 | DTXSID0059790 | sodium;2-iodoacetate | sodiumiodoacetate | Q7763011 | A876151 | sodium iodoacetate | CCRIS 9232 | iodoacetate (Sodium) | Iodoacetic acid, sodium salt | FT-

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

A reagent used to modify cysteine residues in proteins to inhibit cysteine proteases.

Specifications

Sinónimos

EINECS 206-165-7 | E75848 | Iodoacetic acid sodium salt | MFCD00002686 | J-200341 | DTXSID0059790 | sodium;2-iodoacetate | sodiumiodoacetate | Q7763011 | A876151 | sodium iodoacetate | CCRIS 9232 | iodoacetate (Sodium) | Iodoacetic acid, sodium salt | FT-

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Iodoacetic Acid, Sodium Salt is a reagent shown to be used to modify cysteine residues in proteins to ultimately inhibit cysteine proteases. Iodoacetic Acid, Sodium Salt has been observed to slightly inhibit the O-hexyl O-2, 5-dichlorophenyl phosphoramidat

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: C(C(=O)[O-])I.[Na+]
• IUPAC Name: sodium;2-iodoacetate
• InChIKey: AGDSCTQQXMDDCV-UHFFFAOYSA-M
• INCHI: 1S/C2H3IO2.Na/c3-1-2(4)5;/h1H2,(H,4,5);/q;+1/p-1
• Isómeros SMILES: C(C(=O)[O-])I.[Na+]
• WGK Alemania: 3
• RTECS: AI3675000
• Número ONU: 2811
• Peso molecular: 207.93
• Beilstein: 4009322

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Alpha-halocarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Alpha-halocarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Alpha-halocarboxylic acids
• Alternative Parents: Carboxylic acid salts Organic metal halides Monocarboxylic acids and derivatives Carboxylic acids Organoiodides Organic sodium salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl iodides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-halocarboxylic acid - Carboxylic acid salt - Organic metal halide - Carboxylic acid - Organic alkali metal salt - Monocarboxylic acid or derivatives - Alkyl halide - Organic salt - Organooxygen compound - Organoiodide - Organohalogen compound - Organic sodium salt - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organic oxygen compound - Alkyl iodide - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as alpha-halocarboxylic acids. These are carboxylic acids containing a halogen atom bonded to the alpha carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in H2O
• Sensibilidad: Light Sensitive,Hygroscopic
• Punto de fusión (°C): 208°C
• Peso molecular: 207.930 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 207.9 Da
• Monoisotopic Mass: 207.9 Da
• Topological Polar Surface Area: 40.100 Ų
• Heavy Atom Count: 6
• Formal Charge: 0
• Complexity: 46.800
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

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10. Min Song, Weichang Han, Jingyi Li, Gaoyi Wu, Haibo Yu, Qing Yuan, Jiani Yu.  (2025)  Monosodium Iodoacetate Induces Knee Osteoarthritis in Rats in a Dose- and Time-Dependent Manner.  Journal of Pain Research,      [PMID:41127857] [10.2147/JPR.S527135]

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