GRADE & PURITYAnimal Free?Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material.Carrier Free?Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays.Recombinant?Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin.Validated?Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated.ExactAb™?ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications.Low Endotoxin?Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere.Azide Free?Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory.≥90%(SDS-PAGE&SEC-HPLC)
Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
Trastuzumab deruxtecan (anti-ERBB2) is an anti-human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate (ADC). Trastuzumab deruxtecan (anti-ERBB2) is composed of a humanized anti-HER2 antibody, an enzymatically cleavable peptide-linker, a topoisomerase I inhibitor (a toxin component of Dxd). Trastuzumab deruxtecan (anti-ERBB2) can be used for the research of HER2-positive breast cancer and gastric cancer.
Specifications
Product Name
Trastuzumab deruxtecan (anti-ERBB2) - Primary antibody, specific to ERBB2, >90% (SDS-PAGE&SEC), Human IgG1, BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent
Protein tyrosine kinase that is part of several cell surface receptor complexes, but that apparently needs a coreceptor for ligand binding. Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a
BINDING AGENT of Receptor protein-tyrosine kinase erbB-2 binding agent
Isotipo
Human IgG1
Tipo de cadena ligera
kappa
SDS-PAGE
153.75 kDa
Método de purificación
Protein A purified
Pureza
>90% (SDS-PAGE&SEC)
CAS
1826843-81-5
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes
Trastuzumab deruxtecan (anti-ERBB2) (Ab183313) - Flow Cytometry Flow Cytometry analysis of MCF7 cells labelling ERBB2 (red) with Trastuzumab deruxtecan (anti-ERBB2) (Ab183313) at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.
Trastuzumab deruxtecan (anti-ERBB2) (Ab183313) - ELISA Immobilized Recombinant Human ErbB2/HER2 protein (rp169607) at 1.0 μg/mL can bind Trastuzumab deruxtecan (anti-ERBB2) (Ab183313) with the EC₅₀ of 58.19 ng/mL.
Trastuzumab deruxtecan (anti-ERBB2) (Ab183313) - SEC The purity of Trastuzumab deruxtecan (anti-ERBB2) (Ab183313) is more than 95% verified by HPLC.
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
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