Triazavirin - ≥98% , CAS No.928659-17-0

CAS: 928659-17-0 Cat. No.: T413661 Peso molecular: 286.2 PubChem CID: 52947239

GRADE & PURITY ≥98%

Synonyms

D81614 | UNII-G1JE34QF2S | [1,2,4]Triazolo[5,1-c][1,2,4]triazin-4(6H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate (1:1:2) | TRIAZAVIRINE | Sodium 2-methylthio-6-nitro-1,2,4-triazol [5,1c][1,2,3]-triazin-7-one dihydrate | (1,2,4)Triazolo(5,1-C)(1,2,

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Information

Triazavirin Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Triazavirin is an effective protective agent on the transmission stage of influenza.

Specifications

Sinónimos

D81614 | UNII-G1JE34QF2S | [1, 2, 4]Triazolo[5, 1-c][1, 2, 4]triazin-4(6H)-one, 7-(methylthio)-3-nitro-, sodium salt, hydrate (1:1:2) | TRIAZAVIRINE | Sodium 2-methylthio-6-nitro-1, 2, 4-triazol [5, 1c][1, 2, 3]-triazin-7-one dihydrate | (1, 2, 4)Triazolo(5, 1-C)(1, 2,

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Triazavirin (TZV, Riamilovir) is a novel antiviral drug, a nucleoside analogue of nucleic acid that inhibits the synthesis of viral RNA and DNA and replication of genomic fragments. Triazavirin is active against influenza and a number of other viruses. Tr

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Propiedades del producto

• ALogP: -0.184
• Enlace rotable: 2

Nombres e identificadores

• Sonrisas canónicas: CSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
• IUPAC Name: sodium;7-methylsulfanyl-3-nitro-[1,2,4]triazolo[5,1-c][1,2,4]triazin-4-olate;dihydrate
• InChIKey: GDVSBVWTWGUDAW-UHFFFAOYSA-M
• INCHI: 1S/C5H4N6O3S.Na.2H2O/c1-15-5-6-4-8-7-2(11(13)14)3(12)10(4)9-5;;;/h12H,1H3;;2*1H2/q;+1;;/p-1
• Isómeros SMILES: CSC1=NN2C(=C(N=NC2=N1)[N+](=O)[O-])[O-].O.O.[Na+]
• PubChem CID: 52947239
• Peso molecular: 286.2

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organosulfur compounds
    • Clase Thioethers
      • Subclass Aryl thioethers

• Kingdom: Organic compounds
• Superclass: Organosulfur compounds
• Clase: Thioethers
• Subclass: Aryl thioethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Aryl thioethers
• Alternative Parents: Nitroaromatic compounds Alkylarylthioethers 1,2,4-triazines Imidolactams Triazoles Heteroaromatic compounds Sulfenyl compounds Propargyl-type 1,3-dipolar organic compounds Azacyclic compounds Organic oxoazanium compounds Organic oxides Organic sodium salts Hydrocarbon derivatives Organic zwitterions Organonitrogen compounds Organooxygen compounds Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Aryl thioether - Nitroaromatic compound - Alkylarylthioether - Triazine - Imidolactam - 1,2,4-triazine - Azole - 1,2,4-triazole - Heteroaromatic compound - Organic nitro compound - C-nitro compound - Organic alkali metal salt - Azacycle - Organoheterocyclic compound - Organic oxoazanium - Sulfenyl compound - Allyl-type 1,3-dipolar organic compound - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Hydrocarbon derivative - Organic oxygen compound - Organic zwitterion - Organic salt - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic sodium salt - Organic oxide - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as aryl thioethers. These are organosulfur compounds containing a thioether group that is substituted by an aryl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Influenza B virus (2113 Activities)

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Oryctolagus cuniculus (11301 Activities)

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Influenza A virus (11224 Activities)

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MDCK (10148 Activities)

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Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Solubility (25°C) In vitro DMSO: 57 mg/mL (199.16 mM); Water: 20 mg/mL (69.88 mM); Ethanol: Insoluble
• Sensibilidad: Moisture sensitive.
• DMSO (mg/ml) Solubilidad máxima: 57
• DMSO (mM) Solubilidad máxima: 199.16142557652
• Agua (mg/ml) Solubilidad máxima: 20
• Agua (mM) Solubilidad máxima: 69.8812019566737
• Peso molecular: 286.200 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 1
• Exact Mass: 286.01 Da
• Monoisotopic Mass: 286.01 Da
• Topological Polar Surface Area: 152.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 262.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3