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X5050 - ≥98% , CAS No.2404756-81-4
Disponible para pedir
GRADE & PURITY ≥98%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Why this grade
≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
X5050 is a REST inhibitor, with an EC 50 of 2.1 μM.
In Vitro
X5050 (100 µM, 1 day) induces a dosedependent decrease in the REST isoform in protein level. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Western Blot AnalysisCell Line: NSCs. Concentration: 100 µM. Incubation Time: One day. Result: Induced a dosedependent decrease in the 122 kDa longer REST isoform.
In Vivo
X5050 (2 x 2µl of 20 mM) is active in HD pathological context . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: 12-week-old male C57Bl6 mice .2 Dosage: 2 x 2µl of 20 mM in 10% DMSO in water. Administration: Intraventricular injection. Result: Increased BDNF expression. A decrease in Darpp32 and Snap25 expression was found by QRT-PCR in the lesioned striatum as compared with the contralateral striatum. Significantly increased the levels of Bdnf II splice variant (exon II containing variant) while Bdnf IV levels were not significantly changed.
Form:Solid
Specifications
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
X5050 is a REST inhibitor, with an EC 50 of 2.1 μM.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Nombres e identificadores
| Sonrisas canónicas | C=CCONC(=O)C1=CC2=C(C=C1)N=C(N2)C3=CC=CC=C3O |
|---|---|
| IUPAC Name | 2-(2-hydroxyphenyl)-N-prop-2-enoxy-3H-benzimidazole-5-carboxamide |
| InChIKey | RGROIKJLROTDCR-UHFFFAOYSA-N |
| INCHI | 1S/C17H15N3O3/c1-2-9-23-20-17(22)11-7-8-13-14(10-11)19-16(18-13)12-5-3-4-6-15(12)21/h2-8,10,21H,1,9H2,(H,18,19)(H,20,22) |
| PubChem CID | 146301742 |
| Peso molecular | 309.32 |
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Estructura 3D
Modelo de Estructura Química Interactiva
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 100 mg/mL (323.29 mM; Need ultrasonic) |
|---|
Calculadoras de soluciones
Reseñas
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