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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items Z-VAD(OH)-FMK (Caspase Inhibitor VI) - 10mM in DMSO , CAS No.161401-82-7
GRADE & PURITY 10mM in DMSO
Synonyms
Z-Val-Ala-Asp fluoromethylketone | SCHEMBL17494194 | benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone | N-benzyloxycarbonyl-Val-Ala-Asp fluoromethyl ketone | N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone | N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Information
Z-VAD(OH)-FMK (Caspase Inhibitor VI) Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan- caspase inhibitor.
Targets
Caspase
In vitro
Z-VAD(OH)-FMK is the non-methylated form of Z-VAD-FMK, and useful in studies including recombinant, or purified enzymes.
Specifications Sinónimos
Z-Val-Ala-Asp fluoromethylketone | SCHEMBL17494194 | benzyloxycarbonyl-Val-Ala-Asp fluoromethylketone | N-benzyloxycarbonyl-Val-Ala-Asp fluoromethyl ketone | N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone | N-benzyloxycarbonyl-Val-Ala-Asp-fluoromethyl
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Z-VAD(OH)-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Propiedades del producto ALogP 1.246 Recuento HBD 3 Enlace rotable 13
Nombres e identificadores Sonrisas canónicas CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1 IUPAC Name (3S)-5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoic acid InChIKey SUUHZYLYARUNIA-YEWWUXTCSA-N INCHI 1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1 Isómeros SMILES C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CF)NC(=O)[C@H](C(C)C)NC(=O)OCC1=CC=CC=C1 PubChem CID 5497171 Peso molecular 453.46
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Clase Peptidomimetics Subclass Hybrid peptides Intermediate Tree Nodes Not available Direct Parent Hybrid peptides Alternative Parents Dipeptides Valine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Alanine and derivatives Beta amino acids and derivatives Benzyloxycarbonyls Gamma-keto acids and derivatives N-acyl amines Alpha-haloketones Carbamate esters Secondary carboxylic acid amides Organic carbonic acids and derivatives Monocarboxylic acids and derivatives Carboxylic acids Hydrocarbon derivatives Organic oxides Organofluorides Organonitrogen compounds Alkyl fluorides Organopnictogen compounds Molecular Framework Aromatic homomonocyclic compounds Substituents Hybrid peptide - Alpha-dipeptide - Valine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - Beta amino acid or derivatives - Alanine or derivatives - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Benzyloxycarbonyl - Gamma-keto acid - Monocyclic benzene moiety - Fatty amide - Fatty acyl - Keto acid - N-acyl-amine - Benzenoid - Carbamic acid ester - Alpha-haloketone - Carbonic acid derivative - Secondary carboxylic acid amide - Ketone - Carboxamide group - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Carboxylic acid - Organic oxygen compound - Alkyl halide - Hydrocarbon derivative - Organic nitrogen compound - Carbonyl group - Organic oxide - Organopnictogen compound - Alkyl fluoride - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Aromatic homomonocyclic compound Descripción This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas DMSO (mg/ml) Solubilidad máxima 90 DMSO (mM) Solubilidad máxima 198.4739558 Agua (mg/ml) Solubilidad máxima ＜1 Peso molecular 453.500 g/mol XLogP3 1.600 Hydrogen Bond Donor Count 4 Hydrogen Bond Acceptor Count 8 Rotatable Bond Count 13 Exact Mass 453.191 Da Monoisotopic Mass 453.191 Da Topological Polar Surface Area 151.000 Ų Heavy Atom Count 32 Formal Charge 0 Complexity 680.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 3 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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