HEPES - Animal Free, for cell culture, ≥99.5%, Ultra-low endotoxin , CAS No.7365-45-9

CAS: 7365-45-9 Cat. No.: H774625 分子式: C₈H₁₈N₂O₄S 分子量: 238.30 EC番号: 230-907-9

GRADE & PURITY Animal Free, for Cell culture, ≥99.5%, Ultra-low endotoxin

Storage

Protected from light,Room temperature,Argon charged

Shipped In

Normal

概要

useful pH range 6.8 - 8.2 pKa (25 °C) 7.5HEPES is used in many media because it has more buffering capacity in the physiologic pH range of 7.2 - 7.4 at 37°C than sodium bicarbonate. It is commonly added at concentrations between 10 mM and 25 mM. Higher levels cause cytotoxicity. Because bicarbonate is nutritionally necessary for most cells, HEPES should be added in addition to, not in place of, sodium bicarbonate.

Specifications

仕様と純度

Animal Free, for cell culture, ≥99.5%, Ultra-low endotoxin

保管条件

Protected from light,Room temperature,Argon charged

入荷

Normal

等級

Animal Free, 細胞培養用

純度

≥99.5%

名前と識別子

カノニカル・スマイル

C1CN(CCN1CCO)CCS(=O)(=O)O

IUPAC Name

2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

InChIKey

JKMHFZQWWAIEOD-UHFFFAOYSA-N

INCHI

1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

異性体SMILES

C1CN(CCN1CCO)CCS(=O)(=O)O

RTECS

TL6809000

分子量

238.30

Reaxy-Rn

883043

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=883043&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • 分類 Diazinanes
      • Subclass Piperazines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• 分類: Diazinanes
• Subclass: Piperazines
• Intermediate Tree Nodes: Not available
• Direct Parent: N-alkylpiperazines
• Alternative Parents: Sulfonyls Organosulfonic acids Alkanesulfonic acids Trialkylamines 1,2-aminoalcohols Azacyclic compounds Primary alcohols Organopnictogen compounds Organic zwitterions Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: N-alkylpiperazine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - 1,2-aminoalcohol - Tertiary amine - Tertiary aliphatic amine - Alkanolamine - Azacycle - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary alcohol - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Alcohol - Organic zwitterion - Aliphatic heteromonocyclic compound
• 説明: This compound belongs to the class of organic compounds known as n-alkylpiperazines. These are organic compounds containing a piperazine ring where the nitrogen ring atom carries an alkyl group.
• External Descriptors: organosulfonic acid - HEPES

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

化学的性質と物理的性質

• 溶解度: Solvent:water, Max Conc. mg/mL: 238.3, Max Conc. mM: 1000
• 感度: Moisture sensitive.
• 融点（°C）: 210 °C
• 分子量: 238.310 g/mol
• XLogP3: -4.000
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 238.099 Da
• Monoisotopic Mass: 238.099 Da
• Topological Polar Surface Area: 89.500 Ų
• Heavy Atom Count: 15
• Formal Charge: 0
• Complexity: 267.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1