3-AP - ≥98%(HPLC) , CAS No.143621-35-6

Name: 3-AP - ≥98%(HPLC) , CAS No.143621-35-6
SKU: A167286
Availability: InStock

CAS: 143621-35-6 Cat. No.: A167286 분자식: C₇H₉N₅S 분자량: 195.24 EC 번호: 802-845-8

6 Citations COA

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3-AP - ≥98%(HPLC) CAS No(143621-35-6) by Aladdin Scientific

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주문 가능

GRADE & PURITY ≥98%(HPLC)

Synonyms

[(E)-(3-아미노-2-피리딜)메틸렌아미노]티오우레아 | PAN-811 | NSC# 663249 | OCX191 | (e)-2-((3-아미노피리딘-2-일)메틸렌)히드라진-1-카보티오아마이드 | 5,6-dimethyl-2-aminobenzimidazole | SCHEMBL29370 | 3-AP | AS-16679 | NSC-663249 | Pan 811 | U4XIL4091C | DTXS

Storage

20°C에서 보관

Shipped In

아이스 박스 + 아이스 패드

Specifications 제품 특성 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 Citations of This Product 참고 문헌 솔루션 계산기 리뷰

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Why this grade

≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

20°C에서 보관 Ships 아이스 박스 + 아이스 패드 Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

동의어

사양 및 순도

≥98%(HPLC)

생화학 및 생리적 메커니즘

리보뉴클레오티드 환원효소 억제제. 철 킬레이트제이기도 합니다. 백혈병 세포 성장을 억제하고 시스플라틴과 상승 작용을 합니다. 3- 아미노피리딘 카르복스알데히드 티오세미카르바존(3-AP)의 IC50 값은 0.3μM입니다. 항증식 작용을 나타냅니다

보관 조건

20°C에서 보관

배송

아이스 박스 + 아이스 패드

작업 유형

INHIBITOR

순수함

≥98%(HPLC)

제품 특성

ALogP	-0.2

이름과 식별자

Pubchem Sid	504764828
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504764828
정식 스마일	C1=CC(=C(N=C1)C=NNC(=S)N)N
IUPAC Name	[(E)-(3-aminopyridin-2-yl)methylideneamino]thiourea
InChIKey	XMYKNCNAZKMVQN-NYYWCZLTSA-N
INCHI	1S/C7H9N5S/c8-5-2-1-3-10-6(5)4-11-12-7(9)13/h1-4H,8H2,(H3,9,12,13)/b11-4+
이성체 SMILES	C1=CC(=C(N=C1)/C=N/NC(=S)N)N
WGK 독일	3
분자량	195.24
Reaxy-Rn	5811939
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5811939&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - 분류 Pyridines and derivatives
    - Subclass Aminopyridines and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
분류	Pyridines and derivatives
Subclass	Aminopyridines and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Aminopyridines and derivatives
Alternative Parents	Thiosemicarbazones Heteroaromatic compounds Azacyclic compounds Primary amines Organosulfur compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Aminopyridine - Thiosemicarbazone - Heteroaromatic compound - Azacycle - Organic nitrogen compound - Hydrocarbon derivative - Primary amine - Organosulfur compound - Organonitrogen compound - Amine - Aromatic heteromonocyclic compound
설명	This compound belongs to the class of organic compounds known as aminopyridines and derivatives. These are organic heterocyclic compounds containing an amino group attached to a pyridine ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

관련 대상(인간)

RRM2 Tclin Ribonucleoside-diphosphate reductase subunit M2 (1 Activities)

Discover Target: RRM2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CISD1 Tchem CDGSH iron-sulfur domain-containing protein 1 (1 Activities)

Discover Target: CISD1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

RRM2 Tclin Ribonucleoside-diphosphate reductase M2 chain (14 Activities)

Discover Target: RRM2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	날짜	항목
A2218092	Certificate of Analysis	Nov 20, 2024	A167286
A2218104	Certificate of Analysis	Nov 20, 2024	A167286
A2218209	Certificate of Analysis	Nov 20, 2024	A167286
A2218214	Certificate of Analysis	Nov 20, 2024	A167286

용해성	Solvent:DMSO, Max Conc. mg/mL: 19.52, Max Conc. mM: 100
감도	Heat Sensitive
녹는점(°C)	234 °C
분자량	195.250 g/mol
XLogP3	-0.200
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	195.058 Da
Monoisotopic Mass	195.058 Da
Topological Polar Surface Area	121.000 Å²
Heavy Atom Count	13
Formal Charge	0
Complexity	205.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

3-AP - ≥98%(HPLC) , CAS No.143621-35-6

Why this grade

Storage & shipping

Quality documents

Literature proof

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

고객 리뷰

📚 Citations by Application

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