Abiraterone - Moligand™, 10 mM in Ethanol , CAS No.154229-19-3

CAS: 154229-19-3 Cat. No.: A1499175 분자식: C₂₄H₃₁NO 분자량: 349.52 EC 번호: 810-941-6

GRADE & PURITY Moligand™, 10 mM in Ethanol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Abiraterone is a potent and irreversible CYP17A1 inhibitor with antiandrogen activity, which inhibits both the 17α-hydroxylase and 17,20-lyase activity of the cytochrome p450 enzyme CYP17 with IC 50 s of 2.5 nM and 15 nM, respectively.

Specifications

사양 및 순도

Moligand™, 10 mM in Ethanol

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

등급

Moligand™

작업 유형

INHIBITOR

제품 특성

• ALogP: 4.6

이름과 식별자

• 이성체 SMILES: C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)O
• 분자량: 349.52
• Reaxy-Rn: 25096948
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25096948&ln=

참고 문헌

1. Fulin Bi, Yan Lin, Baohong Zhang, Zishan Chen, Jixia Li, Tong Yuan, Jin Yang.  (2025)  Establishing clinically relevant dissolution specifications for prodrug bioequivalence risk assessment: Integration of a dissolution/permeation system with physiologically based biopharmaceutics modeling in abiraterone acetate.  EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS,      [PMID:40925492] [10.1016/j.ejpb.2025.114857]