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Immune Checkpoints

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  1. Recombinant Human IL-2 Protein
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    Recombinant Human IL-2 Protein
    Lyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    In Stock Item #: rp147476
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P60568
    Expression system
    CHO-K1
    Protein Day
    His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    1、Measured in a cell proliferation assay using CTLL‑2 mouse cytotoxic T cells. The ED50 for this effect is typically less than 2.5 ng/mL. 2、Measured in a cell proliferation assay using mouse splenocytes. The ED50 for this effect is typically less than 30.0 ng/mL.
    Synonyms
    IL-2 | T-cell growth factor | TCGF
  2. Recombinant Human TNF RII/TNFRSF1B Protein
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    Recombinant Human TNF RII/TNFRSF1B Protein
    Lyophilized Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. GST Tag ? GST tag grade — recombinant protein bearing a GST tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    In Stock Item #: rp152522
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P20333
    Expression system
    E. coli
    Protein Day
    N-His & GST
    Endotoxin Concentration
    <1.0 EU/mg
    Bioactivity
    The binding activity of TNFRSF1B and TNFa, the EC50 was 0.0470~0.085 μg/ml.
    Synonyms
    CD120b antigen | CD120b | Etanercept | p75 TNF receptor | p75TBPII | p75TNFR | soluble TNFR1B variant 1 | TNF RII | T...
  3. Recombinant Human 4-1BB Ligand Protein - by
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    Recombinant Human 4-1BB Ligand Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)
    In Stock Item #: rp142386
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P41273
    Expression system
    E. coli
    Protein Day
    No tag
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Fully biologically active when compared to standard. The ED50 as determined by stimulation of IL-8 production using human PBMC is less than 10 ng/ml.
    Synonyms
    41BB Ligand | 4-1BB Ligand | 4-1BBL | 4-1BB-L | CD137L | homolog of mouse 4-1BB-L | receptor 4-1BB ligand | TNFSF9 | ...
  4. Recombinant Human CD80 Protein
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    Recombinant Human CD80 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    In Stock Item #: rp144122
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P33681
    Expression system
    HEK293
    Protein Day
    N-His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Measured by its binding activity of recombinant human CD80 and recombinant human CD86. The EC50 for this effect is less than 0.412μg/mL.
    Synonyms
    Activation B7-1 antigen | B7 | BB1 | CTLA-4 counter-receptor B7.1
  5. Recombinant Human Nectin-3 Protein
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    Recombinant Human Nectin-3 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥98%(SDS-PAGE)
    In Stock Item #: rp149161
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    Q9NQS3
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Recombinant Human Nectin-3 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human PVRL1/NECTIN1 hFc has been identified as an interactor of Nectin-3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-3 and recombinant PVRL1/NECTIN1 hFc.
    Synonyms
    CDw113 | Nectin cell adhesion molecule 3 | Poliovirus receptor-related protein 3
  6. Recombinant Mouse IL-2 Protein
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    Recombinant Mouse IL-2 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥98%(SDS-PAGE)
    In Stock Item #: rp154174
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Mouse
    Accession #
    P04351
    Expression system
    HEK293
    Protein Day
    N-His
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Recombinant Mouse IL-2 stimulates cell proliferation of the CTLL-2 mouse cytotoxic T cell line. The ED50 for this effect is typically less than 2.5 ng/mL.
    Synonyms
    Aldesleukin | IL2 | IL-2 | IL-2lymphokine | interleukin 2 | interleukin-2 | involved in regulation of T-cell clonal e...
  7. Recombinant Human Nectin-2/CD112 Protein - by
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    Recombinant Human Nectin-2/CD112 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)
    In Stock Item #: rp149154
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    Q92692
    Expression system
    HEK293
    Protein Day
    No tag
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Recombinant Human Nectin-2/CD112 Protein is a human protein of the immunoglobulin superfamily which forms part of adherens junctions. Human DNAM-1/CD226 hFc has been identified as an interactor of Nectin-2, thus a binding ELISA assay was conducted to detect the interaction of recombinant human Nectin-2 and recombinant DNAM-1/CD226 hFc.
    Synonyms
    CD112 antigen | CD112 | Herpes virus entry mediator B | Herpesvirus entry mediator B | herpesvirus entry protein B | ...
  8. Recombinant Human HVEM/TNFRSF14 Protein
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    Recombinant Human HVEM/TNFRSF14 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. Fc tag ? Fc tag grade — recombinant protein bearing a Fc tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. The Fc tag aids dimerization and protein-A/G capture. ≥95%(SDS-PAGE&HPLC)
    In Stock Item #: rp152533
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    Q92956
    Expression system
    Pichia pastoris
    Protein Day
    C-hFc
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Fully biologically active when compared to standard. The biologically active as determined by its ability to inhibit TNF-beta -mediated cytotoxicity using murine L929 cells.
    Synonyms
    ATAR | CD270 antigen | CD270 | CD40-like protein | Herpes virus entry mediator A | Herpesvirus entry mediator A | Hve...
  9. Recombinant Human IL-10 Protein
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    Recombinant Human IL-10 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE)
    In Stock Item #: rp147355
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P22301
    Expression system
    E. coli
    Protein Day
    No tag
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    1. Measured in a cell proliferation assay using MC/9-2 mouse mast cells. The ED₅₀ for this effect is typically 1.0 - 8.0 ng/mL. 2. Immobilized Recombinant Human IL-10 Protein (rp147355) at 2 μg/mL can bind Recombinant Rhesus IL10RA Protein (Fc Tag) the EC₅₀ for this effect is 100.0 - 300.0 ng/mL.
    Synonyms
    CSIF | CSIFMGC126450 | Cytokine synthesis inhibitory factor | GVHDS | IL10 | IL-10 | IL10A | IL-10MGC126451 | interle...
  10. Recombinant Human CD40 Ligand/TNFSF5 Protein
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    Recombinant Human CD40 Ligand/TNFSF5 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&HPLC)
    In Stock Item #: rp152636
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P29965
    Expression system
    E. coli
    Protein Day
    No tag
    Endotoxin Concentration
    <1.0 EU/μg
    Bioactivity
    Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of IL-8 production by human PBMC is less than 5-10 ng/ml.
    Synonyms
    CD154 antigen | CD154 | CD40 antigen ligand | CD40 Ligand | CD40L | CD40-L | CD40LG | CD40LIGM | gp39 | hCD40L | HIGM...
  11. Recombinant Human CD30-L Protein
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    Recombinant Human CD30-L Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    In Stock Item #: rp143950
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    P32971
    Expression system
    HEK293
    Protein Day
    N-His
    Endotoxin Concentration
    <0.1 EU/μg
    Bioactivity
    Measured by its ability to stimulate IL-6 secretion by HDLM human Hodgkin’s lymphoma cells. The ED50 for this effect is 8-48 ng/mL in the presence of 10 µg/mL of a cross-linking antibody, Mouse Anti-polyHistidine Monoclonal Antibody.
    Synonyms
    CD153 antigen; CD153; CD30 antigen ligand; CD30 Ligand; CD30L; CD30-L; CD30LCD30 ligand; CD30LGMGC138144; TNFSF8; tum...
  12. Recombinant Human B7-H2 Protein
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    Recombinant Human B7-H2 Protein
    Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
    In Stock Item #: rp147187
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    Pricing & Pack Sizes
    Technical Identifiers
    Species
    Human
    Accession #
    O75144
    Expression system
    HEK293
    Protein Day
    C-His
    Endotoxin Concentration
    <0.01 EU/μg
    Bioactivity
    Immobilized Human ICOSLG at 1 μg/mL (100 μL/well) can bind Human ICOS/CD278 with a linear range of 2-15 ng/mL.
    Synonyms
    B7H2 | B7-H2 | B7H2B7 homolog 2 | B7-H2B7-related protein 1 | B7RP-1 | B7RP1B7-like protein Gl50 | LICOS | CD275 anti...
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