AR7 - 10mM in DMSO , CAS No.80306-38-3

CAS: 80306-38-3 Cat. No.: A426075 분자식: C15H12ClNO 분자량: 257.71 EC 번호: 806-133-8
주문 가능
GRADE & PURITY 10mM in DMSO
Synonyms
MFCD27978377 | SCHEMBL12206685 | 7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine | AKOS032946191 | EX-A1249 | BCP25687 | HY-101106 | AR7 | AR-7 | 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine | 7-chloro-3-p-tolyl-2H-benzo[b][1,4]oxazine | NCGC00347937-01 |
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
Size
USA
독일 (EU)*
Price
Qty
1ml
A426075-1ml
2 재고 있음
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US$101.90

US$118.90
저장 US$17.00 (14.30%)
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🧪

Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

AR7 AR7 is a retinoic acid receptor α (RARα) antagonist.


application:

AR7 has been used:

• as chaperone-mediated autophagy (CMA) activator to study the activity of CMA in rat liver lysosomes

• as a CMA activator to study its effects on expression of DEAD-box helicase 3 X-linked (DDX3X), eukaryotic translation initiation factor 4A1 (EIF4A1), and eukaryotic translation initiation factor 4H (EIF4H) in cancer cells

• to study its effects on synuclein α (SNCA) oligomer levels in mature primary cortical neurons


Specifications

동의어
MFCD27978377 | SCHEMBL12206685 | 7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine | AKOS032946191 | EX-A1249 | BCP25687 | HY-101106 | AR7 | AR-7 | 7-Chloro-3-(p-tolyl)-2H-benzo[b][1,4]oxazine | 7-chloro-3-p-tolyl-2H-benzo[b][1,4]oxazine | NCGC00347937-01 |
사양 및 순도
10mM in DMSO
생화학 및 생리적 메커니즘
AR7 is a retinoic acid receptor α (RARα) antagonist.
보관 조건
Store at -80°C
배송
Dry ice packs + Cold packs
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
작업 유형
ANTAGONIST
이름과 식별자
Pubchem Sid528763121
정식 스마일CC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2
IUPAC Name7-chloro-3-(4-methylphenyl)-2H-1,4-benzoxazine
InChIKeyMVOZLTFXYGHZPM-UHFFFAOYSA-N
INCHI1S/C15H12ClNO/c1-10-2-4-11(5-3-10)14-9-18-15-8-12(16)6-7-13(15)17-14/h2-8H,9H2,1H3
이성체 SMILES CC1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)OC2
WGK 독일 3
분자량 257.71
Reaxy-Rn 20039175
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=20039175&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
분류Benzoxazines
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentBenzoxazines
Alternative Parents Toluenes  Alkyl aryl ethers  Aryl chlorides  Ketimines  Propargyl-type 1,3-dipolar organic compounds  Oxacyclic compounds  Azacyclic compounds  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzoxazine - Alkyl aryl ether - Toluene - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Ketimine - Oxacycle - Azacycle - Ether - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Hydrocarbon derivative - Imine - Organic oxygen compound - Organohalogen compound - Organochloride - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound
설명This compound belongs to the class of organic compounds known as benzoxazines. These are organic compounds containing a benzene fused to an oxazine ring (a six-membered aliphatic ring with four carbon atoms, one oxygen atom, and one nitrogen atom).
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot NumberCertificate Type날짜항목
H2429011Certificate of AnalysisJul 04, 2026 A426075
화학 및 물리적 특성
분자량257.709 g/mol
XLogP34.100
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass257.061 Da
Monoisotopic Mass257.061 Da
Topological Polar Surface Area21.600 Ų
Heavy Atom Count18
Formal Charge0
Complexity322.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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