ASP6432 - ≥95% , CAS No.1282549-08-9

CAS: 1282549-08-9 Cat. No.: A648487 분자식: C₂₆H₃₁KN₄O₆S₂ 분자량: 598.78 PubChem CID: 138454774

GRADE & PURITY ≥95%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

개요

ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC 50 s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively

In Vitro

ASP6432 inhibits the LPA-induced proliferation of human prostate stromal cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: 11 nM (human LPA1), 30 nM (rat LPA1)

Specifications

사양 및 순도

≥95%

생화학 및 생리적 메커니즘

ASP6432 is a potent and selective type 1 lysophosphatidic acid receptor (LPA1) antagonist with IC 50 s of 11 nM and 30 nM for human LPA1 and rat LPA1, respectively.

보관 조건

Store at 2-8°C,Desiccated

배송

Wet ice

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작업 유형

ANTAGONIST

순수함

≥95%

이름과 식별자

• 정식 스마일: CCNS(=O)(=O)[N-]C(=O)C1=CSC(=N1)CN(CCCC2=CC=CC=C2)C(=O)C3=CC(=C(C(=C3)OC)C)OC.[K+]
• IUPAC Name: potassium;[2-[[(3,5-dimethoxy-4-methylbenzoyl)-(3-phenylpropyl)amino]methyl]-1,3-thiazole-4-carbonyl]-(ethylsulfamoyl)azanide
• InChIKey: WKYBXXHNGOTYDD-UHFFFAOYSA-M
• INCHI: 1S/C26H32N4O6S2.K/c1-5-27-38(33,34)29-25(31)21-17-37-24(28-21)16-30(13-9-12-19-10-7-6-8-11-19)26(32)20-14-22(35-3)18(2)23(15-20)36-4;/h6-8,10-11,14-15,17,27H,5,9,12-13,16H2,1-4H3,(H,29,31);/q;+1/p-1
• PubChem CID: 138454774
• MeSH 용어: ASP6432;potassium 1-(2-((3,5-dimethoxy-4-methyl-N-(3-phenylpropyl)benzamido)methyl)-1,3-thiazole-4-carbonyl)-3-ethyl-2,2-dioxo-2lambda6-diazathian-1-ide
• 분자량: 598.78

화학 및 물리적 특성

• 용해성: DMSO : 250 mg/mL (417.52 mM; Need ultrasonic)