Axitinib-13C,d3 - ≥97% , CAS No.1261432-00-1

CAS: 1261432-00-1 Cat. No.: A646210 분자식: C₂₁¹³CH₁₅D₃N₄OS 분자량: 390.48

등급 & 순도 ≥97%

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Axitinib- 13 C,d 3 is a 13 C-labeled and deuterium labeled Axitinib. Axitinib is a multi-targeted tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1, VEGFR2, VEGFR3 and PDGFRβ , respectively.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

사양

사양 및 순도

≥97%

생화학 및 생리적 메커니즘

Axitinib- 13 C,d 3 is a 13 C-labeled and deuterium labeled Axitinib. Axitinib is a multi-targeted tyrosine kinase inhibitor with IC50s of 0.1, 0.2, 0.1-0.3, 1.6 nM for VEGFR1 , VEGFR2 , VEGFR3 and PDGFRβ , respectively.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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작업 유형

INHIBITOR

순수함

≥97%

이름과 식별자

분자량

390.48