Azure C - Moligand™, Dye content ≥40 % , CAS No.531-57-7

CAS: 531-57-7 Cat. No.: A1524004 분자식: C₁₃H₁₂ClN₃S 분자량: 277.77 PubChem CID: 135421845

GRADE & PURITY Moligand™, Dye content ≥40 %

Storage

Store at 2-8°C,Protected from light,Argon charged

Shipped In

Wet ice

개요

Azure C acts as a tau oligomer modulator and Aβ42 oligomerization inhibitor. It regulates hsp70 ATPase activity, thereby mediating the clearance of tau protein. Azure C reduces the levels of toxic tau oligomers by promoting the formation of non-toxic tau aggregates, rescues neuroblastoma cells from tau oligomer-induced toxicity, and binds to and inhibits Aβ42 oligomerization without suppressing its fibrillization. Azure C is generated via sequential oxidation of methylene blue or Azure B through a horseradish peroxidase-mediated reaction, and accumulates in HRP reaction media. Azure C can be used in studies related to tauopathies, including Alzheimer's disease.

Specifications

사양 및 순도

Moligand™, Dye content ≥40 %

보관 조건

Store at 2-8°C,Protected from light,Argon charged

배송

Wet ice

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등급

Moligand™

이름과 식별자

• 이성체 SMILES: CN=C1C=CC2=[NH+]C3=C(C=C(C=C3)N)SC2=C1.[Cl-]
• PubChem CID: 135421845
• 분자량: 277.77