Bezisterim - Moligand™, 10 mM in DMSO , CAS No.1001100-69-1

CAS: 1001100-69-1 Cat. No.: B1494053 Molecular Weight: 330.46 EC Number: 880-101-1 PubChem CID: 16739648
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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Desiccated,Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
B1494053-1ml
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$347.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Bezisterim (HE 3286; NE-3107) is a synthetic derivative of a natural anti-inflammatory steroid, β-AET. Bezisterim is an orally active partial NF-κB inhibitor. HE3286 reduces proinflammatory signals, including IL-6 and matrix metallopeptidase 3. Bezisterim freely penetrates the blood brain barrierin mice. Bezisterim can be used for the research of the ulcerative colitis, arthritis, experimental autoimmune encephalomyelitis. Bezisterim is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Desiccated, Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Names and Identifiers
Isomeric SMILES C[C@]12CC[C@@H](CC1=C[C@@H]([C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C)O)O
PubChem CID 16739648
Molecular Weight 330.46

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
References
1. Kaili Liu, Jianli Li, Zhiwei Sun, Yuheng Sun, Xuerui Zhang, Yang Sui, Zhongyuan Qu, Xiang Zou.  (2025)  Chelidonine-induced inhibition of FBP1 disrupts M2 macrophage polarization and attenuates breast cancer.  PHYTOMEDICINE,      [PMID:41175579] [10.1016/j.phymed.2025.157451]
2. Yin Xuanying, Qiu Jinmei, Cheng Guowang, Wu Jiaxin, Wang Chen, Zheng Chunye, Huang Shuiqing, Chen Tongkai.  (2025)  Biomimetic nanodelivery system with simultaneous blood–brain barrier-crossing and neuroprotective abilities for anti-parkinsonian therapy.  Chinese Medicine,  20  (1): (1-24).  [PMID:41204267] [10.1186/s13020-025-01239-2]
3. Zhongyuan Qu, Huimin Li, Fajing Qiang, Kaili Liu, Shuang Wu, Jianli Li, Xiang Zou.  (2025)  Regulation of inflammation by Chaihu-Shugan-San: Targeting the IL-17/ NF-κB pathway to combat breast cancer-related depression.  PHYTOMEDICINE,      [PMID:40382939] [10.1016/j.phymed.2025.156836]
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