≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
BMS 193885 is a potent, competitive NPY1-R antagonist (K|i|= 3.3 nM, IC|50|= 5.9 nM) that displays > 47, > 100, > 160, > 160 and > 160-fold selectivity over σ1, α1, NPY2-R, NPY4-R and NPY5-R receptors respectively. Reduces food intake and body weight via central NPY1-R inhibition and is a brain penetrant.
| Ki 데이터 | NPY1-R: Ki= 3.3 nM |
|---|
| Pubchem Sid | 504765156 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504765156 |
| 정식 스마일 | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)NC(=O)NCCCN3CCC(CC3)C4=CC(=CC=C4)OC)C(=O)OC |
| IUPAC Name | dimethyl 4-[3-[3-[4-(3-methoxyphenyl)piperidin-1-yl]propylcarbamoylamino]phenyl]-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate |
| InChIKey | WMYSXJSJXZFODY-UHFFFAOYSA-N |
| INCHI | 1S/C33H42N4O6/c1-21-28(31(38)42-4)30(29(22(2)35-21)32(39)43-5)25-10-6-11-26(19-25)36-33(40)34-15-8-16-37-17-13-23(14-18-37)24-9-7-12-27(20-24)41-3/h6-7,9-12,19-20,23,30,35H,8,13-18H2,1-5H3,(H2,34,36,40) |
| 이성체 SMILES | CC1=C(C(C(=C(N1)C)C(=O)OC)C2=CC(=CC=C2)NC(=O)NCCCN3CCC(CC3)C4=CC(=CC=C4)OC)C(=O)OC |
| WGK 독일 | 3 |
| 분자량 | 590.71 |
| Reaxy-Rn | 9104068 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=9104068&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| 분류 | Piperidines |
| Subclass | Phenylpiperidines |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Phenylpiperidines |
| Alternative Parents | N-phenylureas Dihydropyridinecarboxylic acids and derivatives Anisoles Phenoxy compounds Methoxybenzenes Aralkylamines Alkyl aryl ethers Dicarboxylic acids and derivatives Enoate esters Vinylogous amides Methyl esters Amino acids and derivatives Trialkylamines Ureas Enamines Dialkylamines Azacyclic compounds Carbonyl compounds Hydrocarbon derivatives Organic oxides |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Phenylpiperidine - N-phenylurea - Dihydropyridinecarboxylic acid derivative - Phenoxy compound - Anisole - Methoxybenzene - Phenol ether - Alkyl aryl ether - Dihydropyridine - Aralkylamine - Monocyclic benzene moiety - Dicarboxylic acid or derivatives - Hydropyridine - Benzenoid - Alpha,beta-unsaturated carboxylic ester - Vinylogous amide - Enoate ester - Methyl ester - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Urea - Carboxylic acid ester - Secondary amine - Azacycle - Ether - Enamine - Carboxylic acid derivative - Secondary aliphatic amine - Organic oxygen compound - Amine - Organic oxide - Carbonyl group - Organic nitrogen compound - Hydrocarbon derivative - Organonitrogen compound - Organooxygen compound - Aromatic heteromonocyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 C2618241 | Certificate of Analysis | Mar 31, 2026 | B332143 |
| B2307342 | Certificate of Analysis | Nov 07, 2022 | B332143 |
| B2307343 | Certificate of Analysis | Nov 07, 2022 | B332143 |
| B2307346 | Certificate of Analysis | Nov 07, 2022 | B332143 |
| B2307374 | Certificate of Analysis | Nov 07, 2022 | B332143 |
| B2307390 | Certificate of Analysis | Nov 07, 2022 | B332143 |
| 용해성 | Soluble in water (20 mM), and DMSO (100 mM). |
|---|---|
| 굴절률 | n20D~1.57 (Predicted) |
| 분자량 | 590.700 g/mol |
| XLogP3 | 4.200 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 12 |
| Exact Mass | 590.31 Da |
| Monoisotopic Mass | 590.31 Da |
| Topological Polar Surface Area | 118.000 Ų |
| Heavy Atom Count | 43 |
| Formal Charge | 0 |
| Complexity | 1010.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
