≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 5 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
D-(-)-Pantolactone is a chiral auxiliary used in many asymmetric synthesis reactions.
It can be used as a chiral starting material to synthesize:
• An insect sex pheromone named 1S,2S,3R-1-acetoxymethyl-2,3,4,4-tetrameth-ylcyclopentane.
• (-)-Enantiomer of (R)-8-hydroxy-4,7,7-trimethyl-7,8-dihydrocyclopenta[e]isoindole-1,3(2H,6H)-dione, a norsesquiterpene alkaloid.
• A bicyclic diterpene named isofregenedadio
| Pubchem Sid | 508810420 |
|---|---|
| 정식 스마일 | CC1(COC(=O)C1O)C |
| IUPAC Name | (3R)-3-hydroxy-4,4-dimethyloxolan-2-one |
| InChIKey | SERHXTVXHNVDKA-BYPYZUCNSA-N |
| INCHI | 1S/C6H10O3/c1-6(2)3-9-5(8)4(6)7/h4,7H,3H2,1-2H3/t4-/m0/s1 |
| 이성체 SMILES | CC1(COC(=O)[C@@H]1O)C |
| WGK 독일 | 1 |
| 분자량 | 130.14 |
| Beilstein | 24854272 |
| Reaxy-Rn | 80958 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=80958&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| 분류 | Lactones |
| Subclass | Gamma butyrolactones |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Gamma butyrolactones |
| Alternative Parents | Tetrahydrofurans Secondary alcohols Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organic oxides Hydrocarbon derivatives Carbonyl compounds |
| Molecular Framework | Aliphatic heteromonocyclic compounds |
| Substituents | Gamma butyrolactone - Tetrahydrofuran - Secondary alcohol - Carboxylic acid ester - Oxacycle - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Carbonyl group - Alcohol - Aliphatic heteromonocyclic compound |
| 설명 | This compound belongs to the class of organic compounds known as gamma butyrolactones. These are compounds containing a gamma butyrolactone moiety, which consists of an aliphatic five-member ring with four carbon atoms, one oxygen atom, and bears a ketone group on the carbon adjacent to the oxygen atom. |
| External Descriptors | butan-4-olide |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | 날짜 | 항목 |
|---|---|---|---|
 C2522077 | Certificate of Analysis | Apr 01, 2025 | P122332 |
| D2402399 | Certificate of Analysis | Mar 20, 2024 | P122332 |
| D2402400 | Certificate of Analysis | Mar 20, 2024 | P122332 |
| D2402401 | Certificate of Analysis | Mar 20, 2024 | P122332 |
| D2402402 | Certificate of Analysis | Mar 20, 2024 | P122332 |
| D2402403 | Certificate of Analysis | Mar 20, 2024 | P122332 |
| K2505134 | Certificate of Analysis | Mar 20, 2024 | P122332 |
| A1507060 | Certificate of Analysis | Sep 21, 2022 | P122332 |
| K1812054 | Certificate of Analysis | Sep 15, 2022 | P122332 |
| E1814027 | Certificate of Analysis | Mar 08, 2022 | P122332 |
| H2310025 | Certificate of Analysis | Mar 20, 2021 | P122332 |
| 감도 | Moisture Sensitive |
|---|---|
| 특정 회전[α] | [α]25/D −49.8°, c = 2 in H2O |
| 끓는점(°C) | 120-122°C/15mm |
| 녹는점(°C) | 92°C |
| 분자량 | 130.139 g/mol |
| XLogP3 | 0.500 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 0 |
| Exact Mass | 130.063 Da |
| Monoisotopic Mass | 130.063 Da |
| Topological Polar Surface Area | 46.500 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 139.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Xiao-Jian Zhang, Min Cao, Yi-Fei Luo, Meng-Yu Huang, Fang-Ying Zhu, Zhi-Qiang Liu, Yu-Guo Zheng. (2023) Efficient synthesis of D-pantolactone in monophase and organic-aqueous biphase reaction biosystem using a novel conjugated polyketide reductase based on integrated substrate pocket alteration. BIOCHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.bej.2023.109088] |
| 2. Yaling Huang, Junwen Wan, Min Sun, Tao Feng, Qian Liu, Shiqing Song, Xiaoming Zhang, Chi-Tang Ho. (2022) Flavor profile disclosure of Chinese steamed breads (CSBs) by sensomics approach. Food Bioscience, [PMID:] [10.1016/j.fbio.2022.102198] |
| 3. Jing Wang, Ruifang Wang, Junyi Wang, Yan Gao, Lina Qiao, Ning Zhang. (2025) Recognition of characteristic aroma-active components in Qingke (highand barley) through flavoromics analysis. FOOD CHEMISTRY, [PMID:40602137] [10.1016/j.foodchem.2025.145262] |
| 4. Xiaoqian Liu, Fang Yuan, Bei Zhou, Wen Huang, Zhinan Mei, Salam A. Ibrahim, Ying Liu, Xi Feng. (2025) Application of GC-O, aroma recombination and omission tests to identify horse urine-like off-odor in Gastrodia elata Blume. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.107905] |
| 5. Ken Zheng, Ai-Ping Pang, Fang-Ying Zhu, Yu-Hui Liu, Xiao-Jian Zhang, Qing Yang, Xiang-Yang Li, Jun-ping Zhou, Bo Zhang, Zhi-Qiang Liu, Yu-Guo Zheng. (2026) Rational selection of ketopantoate hydroxymethyltransferase with low product feedback inhibition based on binding free energy calculation analysis. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, [PMID:42429766] [10.1128/aem.00267-26] |
