Dimethyl-bisphenol A - ≥99% , CAS No.1568-83-8

CAS: 1568-83-8 Cat. No.: D275158 분자식: C₁₇H₂₀O₂ 분자량: 256.34

GRADE & PURITY ≥99%

Synonyms

HIF-1alpha inhibitor | KSC-7-226 | BISPHENOLADIMETHYLETHER | DTXSID30347091 | 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene | MFCD00984727 | OJYIBEYSBXIQOP-UHFFFAOYSA-N | 1-Methoxy-4-[1-(4-methoxyphenyl)-1-methylethyl]benzene # | HY-115746 | AKOS003

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications

동의어

HIF-1alpha inhibitor | KSC-7-226 | BISPHENOLADIMETHYLETHER | DTXSID30347091 | 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene | MFCD00984727 | OJYIBEYSBXIQOP-UHFFFAOYSA-N | 1-Methoxy-4-[1-(4-methoxyphenyl)-1-methylethyl]benzene # | HY-115746 | AKOS003

사양 및 순도

≥99%

생화학 및 생리적 메커니즘

HIF-1α inhibitor that promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Inhibits steroidogenesis and down regulates rate-limiting enzymes (StAR) in the estradiol biosynthesis pathway.Dimethyl-bisphenol A (DMBPA) is a potent HIF-1α

보관 조건

Store at -20°C,Desiccated

배송

Ice chest + Ice pads

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참고

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

순수함

≥99%

이름과 식별자

• Pubchem Sid: 504759558
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504759558
• 정식 스마일: CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC
• IUPAC Name: 1-methoxy-4-[2-(4-methoxyphenyl)propan-2-yl]benzene
• InChIKey: OJYIBEYSBXIQOP-UHFFFAOYSA-N
• INCHI: 1S/C17H20O2/c1-17(2,13-5-9-15(18-3)10-6-13)14-7-11-16(19-4)12-8-14/h5-12H,1-4H3
• 이성체 SMILES: CC(C)(C1=CC=C(C=C1)OC)C2=CC=C(C=C2)OC
• 분자량: 256.34
• Reaxy-Rn: 1879104
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1879104&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • 분류 Benzene and substituted derivatives
      • Subclass Diphenylmethanes

• Kingdom: Organic compounds
• Superclass: Benzenoids
• 분류: Benzene and substituted derivatives
• Subclass: Diphenylmethanes
• Intermediate Tree Nodes: Not available
• Direct Parent: Diphenylmethanes
• Alternative Parents: Phenylpropanes Phenoxy compounds Methoxybenzenes Anisoles Alkyl aryl ethers Hydrocarbon derivatives
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Diphenylmethane - Phenylpropane - Phenoxy compound - Methoxybenzene - Phenol ether - Anisole - Alkyl aryl ether - Ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as diphenylmethanes. These are compounds containing a diphenylmethane moiety, which consists of a methane wherein two hydrogen atoms are replaced by two phenyl groups.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

화학 및 물리적 특성

• 용해성: Soluble in ethanol to 75 mM and in DMSO to 100 mM
• 분자량: 256.339 g/mol
• XLogP3: 4.000
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 256.146 Da
• Monoisotopic Mass: 256.146 Da
• Topological Polar Surface Area: 18.500 Ų
• Heavy Atom Count: 19
• Formal Charge: 0
• Complexity: 232.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

참고 문헌

1. Xiaoye Cheng, Yijin Jiang, Xu Zhao, Nana Ma, Xiangzhen Shen.  (2024)  Regulation of lactate accumulation in bovine mammary epithelial cells by LPS-induced HIF-1α/MCT1 pathway.  MICROBIAL PATHOGENESIS,      [PMID:39725042] [10.1016/j.micpath.2024.107261]

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1568-83-8, the molecular formula is C17H20O2, and the molecular weight is 256.34 g/mol. InChIKey OJYIBEYSBXIQOP-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.