Ec2la - Moligand™, ≥98%(HPLC) , Allosteric modulator of CB 2 receptor, CAS No.2244579-87-9, Allosteric modulator of CB 2 receptor

CAS: 2244579-87-9 Cat. No.: E288545 분자식: C21H24BrFN2O2 분자량: 435.33
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
Synonyms
N-[5-Bromo-1-[(4-fluorophenyl)methyl]-1,2-dihydro-4-methyl-2-oxo-3-pyridinyl]cycloheptanecarboxamide | CB2R PAM
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Size
USA
독일 (EU)*
Price
Qty
1mg
E288545-1mg
주문제작 · 8~12주
US$125.90
5mg
E288545-5mg
6 재고 있음
US$439.90
10mg
E288545-10mg
5 재고 있음
US$719.90
25mg
E288545-25mg
3 재고 있음
US$999.90
50mg
E288545-50mg
3 재고 있음
US$1,399.90
100mg
E288545-100mg
3 재고 있음
US$1,999.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

동의어
N-[5-Bromo-1-[(4-fluorophenyl)methyl]-1,2-dihydro-4-methyl-2-oxo-3-pyridinyl]cycloheptanecarboxamide | CB2R PAM
사양 및 순도
Moligand™, ≥98%(HPLC)
생화학 및 생리적 메커니즘
CB2receptor positive allosteric modulator. EnhancesCP 55940 and 2-Arachidonylglycerol-stimulated binding of [35S]GTPγS to CB2receptors, but has no effect in the absence of agonist. Exhibits antinociceptive effects in an animal model of neuropathic pain.
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
ALLOSTERIC MODULATOR
작동 메커니즘
Allosteric modulator of CB 2 receptor
순수함
≥98%(HPLC)
이름과 식별자
Pubchem Sid504773499
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504773499
정식 스마일CC1=C(C(=O)N(C=C1Br)CC2=CC=C(C=C2)F)NC(=O)C3CCCCCC3
IUPAC NameN-[5-bromo-1-[(4-fluorophenyl)methyl]-4-methyl-2-oxopyridin-3-yl]cycloheptanecarboxamide
InChIKeyNSGDYZCDUPSTQT-UHFFFAOYSA-N
INCHI1S/C21H24BrFN2O2/c1-14-18(22)13-25(12-15-8-10-17(23)11-9-15)21(27)19(14)24-20(26)16-6-4-2-3-5-7-16/h8-11,13,16H,2-7,12H2,1H3,(H,24,26)
이성체 SMILES CC1=C(C(=O)N(C=C1Br)CC2=CC=C(C=C2)F)NC(=O)C3CCCCCC3
분자량 435.33
Reaxy-Rn 33991973
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33991973&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
CNR2 Tchem Cannabinoid receptor 2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CNR1 Tclin Cannabinoid CB1 receptor (20913 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CNR2 Tchem Cannabinoid CB2 receptor (16942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
관련 대상(비인간)
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

11 results found

Lot NumberCertificate Type날짜항목
F2307405Certificate of AnalysisMar 11, 2026 E288545
F2307390Certificate of AnalysisMay 08, 2023 E288545
F2307393Certificate of AnalysisMay 08, 2023 E288545
F2307394Certificate of AnalysisMay 08, 2023 E288545
F2307398Certificate of AnalysisMay 08, 2023 E288545
F2307401Certificate of AnalysisMay 08, 2023 E288545
F2307403Certificate of AnalysisMay 08, 2023 E288545
F2308065Certificate of AnalysisMay 08, 2023 E288545
F2308070Certificate of AnalysisMay 08, 2023 E288545
F2308071Certificate of AnalysisMay 08, 2023 E288545
F2309405Certificate of AnalysisMay 08, 2023 E288545

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화학 및 물리적 특성
용해성Solvent:DMSO, Max Conc. mg/mL: 8.71, Max Conc. mM: 20
분자량435.300 g/mol
XLogP34.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count4
Exact Mass434.101 Da
Monoisotopic Mass434.101 Da
Topological Polar Surface Area49.400 Ų
Heavy Atom Count27
Formal Charge0
Complexity630.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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