6-Bromohexyl(trimethyl)azanium Bromide: FAQs & Key Facts

6-bromohexyl(trimethyl)azanium,bromide is a bifunctional quaternary ammonium salt featuring both a terminal alkyl bromide and a permanently charged trimethylammonium head group, making it a versatile building block for organic synthesis, surface chemistry, and materials science research.

Product Name

6-bromohexyl(trimethyl)azanium,bromide

SKU

B1523102

Functional Groups

Terminal alkyl bromide and quaternary ammonium (trimethylammonium) group

Compound Class

Quaternary ammonium salt (zwitterionic precursor / cationic surfactant intermediate)

Physical Form

Typically a solid salt at room temperature

Key Applications

Organic synthesis building block, phase transfer catalysis, surface functionalization, polymer chemistry

Supplier

Aladdin Scientific

What Is 6-Bromohexyl(trimethyl)azanium Bromide?

6-Bromohexyl(trimethyl)azanium bromide (SKU: B1523102) is a quaternary ammonium salt in which a six-carbon alkyl chain bridges a terminal C–Br electrophile and a permanently positively charged trimethylammonium nitrogen. The molecule exists as a bromide salt and is water-soluble due to its ionic character.

The dual reactivity of this compound is chemically significant: the alkyl bromide terminus acts as an electrophile available for nucleophilic substitution (S_N2) reactions, while the quaternary ammonium group provides a fixed cationic charge that can mediate ionic interactions, influence solubility, or serve as a site for further structural elaboration.

Because it combines these two functional handles in a single, commercially available molecule, it is valued as an efficient linker or precursor in multi-step synthetic routes.

What Are the Typical Applications?

Researchers use 6-bromohexyl(trimethyl)azanium bromide across several disciplines:

• Organic synthesis: The reactive alkyl bromide undergoes S_N2 reactions with a wide range of nucleophiles (amines, thiols, azides, carboxylates), enabling rapid construction of more complex quaternary ammonium-containing architectures.
• Surface and materials chemistry: The compound can be used to introduce cationic quaternary ammonium groups onto surfaces, nanoparticles, or polymer backbones, imparting antimicrobial or ion-exchange properties.
• Polymer chemistry: It serves as a monomer precursor or a post-polymerization modification reagent in the preparation of cationic polymers and polyelectrolytes.
• Phase transfer catalysis research: Quaternary ammonium salts are classical phase transfer catalysts; this bifunctional derivative may be employed in the design of supported or tethered catalysts.
• Biochemical probes: The six-carbon spacer and cationic head group are structural motifs found in lipid-mimicking and membrane-active compounds, making this reagent useful in the synthesis of lipid analogues or drug delivery vectors.

How Should This Compound Be Handled and Stored?

As with all alkyl bromide-containing quaternary ammonium salts, appropriate safety precautions should be observed:

• Personal protective equipment (PPE): Wear chemical-resistant gloves, a lab coat, and eye protection when handling. Work in a well-ventilated area or a fume hood, particularly when weighing powders.
• Storage: Store in a cool, dry place away from light and moisture. Recommended storage temperature is typically 2–8 °C or room temperature under desiccating conditions; consult the product label or Certificate of Analysis (CoA) for confirmed conditions specific to the supplied lot.
• Stability: The alkyl bromide moiety may be susceptible to hydrolysis over time in the presence of moisture. Keep the container tightly sealed after each use.
• Disposal: Dispose of in accordance with local institutional and governmental regulations for halogenated organic waste and quaternary ammonium compounds.

Always consult the Safety Data Sheet (SDS) provided by Aladdin Scientific before first use.

Purity, Specifications, and Quality Assurance

Aladdin Scientific supplies 6-bromohexyl(trimethyl)azanium bromide (B1523102) with quality specifications documented in a Certificate of Analysis (CoA) available on request or via the product page. Key specification parameters to review include:

• Identity confirmation: Typically confirmed by ¹H NMR spectroscopy and/or mass spectrometry.
• Purity: Assessed by HPLC, NMR, or titration methods; the specific purity grade and acceptance criterion are stated on the CoA for each lot.
• Appearance: White to off-white solid.

If your application requires a specific purity threshold (e.g., ≥97%, ≥98%), please contact Aladdin Scientific's technical support team to confirm lot availability or to request a custom specification.

How to Order and What to Expect

6-Bromohexyl(trimethyl)azanium bromide is available from Aladdin Scientific under SKU B1523102. To place an order:

1. Search for B1523102 on the Aladdin Scientific website or contact your regional sales representative.
2. Select the required pack size and confirm availability and lead time with the sales team.
3. Request the CoA and SDS prior to shipment to facilitate your institutional safety approval process.

Standard shipping conditions apply for solid organic reagents. Aladdin Scientific recommends reviewing the shipping and storage conditions listed on the product page, as well as your institution's chemical receiving guidelines, to ensure product integrity upon arrival.

Frequently asked questions

What is the CAS number or molecular formula of 6-bromohexyl(trimethyl)azanium bromide?

The molecular formula of 6-bromohexyl(trimethyl)azanium bromide is C9H21BrN·Br (as a bromide salt). For the confirmed CAS number, please refer to the product page for B1523102 on the Aladdin Scientific website or the accompanying Certificate of Analysis, as specific registry numbers should be verified from the official product documentation.

Is 6-bromohexyl(trimethyl)azanium bromide soluble in water and common organic solvents?

As a quaternary ammonium salt, 6-bromohexyl(trimethyl)azanium bromide is generally soluble in polar protic solvents such as water and methanol due to its ionic character. Solubility in aprotic polar solvents such as DMSO and DMF is also typically observed. Solubility in non-polar solvents is expected to be low. Always perform a small-scale solubility test under your specific experimental conditions before preparing bulk solutions.

Can this compound be used directly as a phase transfer catalyst?

While 6-bromohexyl(trimethyl)azanium bromide contains the quaternary ammonium motif characteristic of phase transfer catalysts, the presence of the reactive terminal alkyl bromide means it may also participate in reactions rather than acting purely as a catalyst. It is more commonly employed as a building block or linker for constructing catalyst structures or functionalized materials. If phase transfer catalysis is your goal, consult the synthetic literature for your specific reaction to confirm suitability.

What storage conditions are recommended to maximize shelf life?

To maximize shelf life, store 6-bromohexyl(trimethyl)azanium bromide in a tightly sealed container under dry conditions, protected from light and moisture. Refrigerated storage (2–8 °C) is generally advisable for long-term stability of alkyl bromide-containing salts. Always verify the recommended storage conditions on the Aladdin Scientific product label or CoA for the specific lot you receive.

How do I request a Safety Data Sheet (SDS) or Certificate of Analysis (CoA) for B1523102?

The SDS and CoA for B1523102 (6-bromohexyl(trimethyl)azanium bromide) can be accessed through the Aladdin Scientific product page on the company website. If they are not immediately available for download, please contact Aladdin Scientific customer service with your lot number and they will provide the relevant documentation promptly.

References

1. March, J. Advanced Organic Chemistry: Reactions, Mechanisms, and Structure. Wiley-Interscience. General reference for S_N2 reactivity of alkyl bromides and quaternary ammonium salt chemistry.
2. Starks, C. M.; Liotta, C. L.; Halpern, M. Phase-Transfer Catalysis: Fundamentals, Applications, and Industrial Perspectives. Chapman & Hall, 1994. Reference for quaternary ammonium salts as phase transfer catalysts.
3. Aladdin Scientific. Product page and Certificate of Analysis for B1523102: 6-bromohexyl(trimethyl)azanium,bromide. Aladdin Scientific (www.aladdin-e.com).

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.