AK5 Mouse mAb: FAQs on Specificity, Use & Storage

AK5 Mouse mAb is a mouse-derived monoclonal antibody targeting adenylate kinase 5 (AK5), supplied by Aladdin Scientific (catalog number Ab350173) in a PBS-only formulation for use in immunological research applications.

Catalog Number

Ab350173

Antibody Type

Mouse Monoclonal Antibody (mAb)

Target

AK5 (Adenylate Kinase 5)

Formulation

PBS only (no preservatives or carrier proteins stated)

Source / Clone Origin

Mouse

Supplier Reference

absea #KC-30233

What Is AK5 and Why Is It Studied?

Adenylate kinase 5 (AK5) is a member of the adenylate kinase family of phosphotransferase enzymes. These enzymes catalyze the reversible transfer of phosphate groups between adenine nucleotides, playing a critical role in cellular energy homeostasis and nucleotide metabolism. AK5 is predominantly expressed in the brain, where it has been associated with neuronal energy balance and, in some contexts, has been identified as an autoantigen in autoimmune encephalitis. Research interest in AK5 spans neuroscience, autoimmune disease investigation, and cancer biology.

Note: Specific expression data, disease associations and functional details beyond textbook-level enzymatic function should be verified against current primary literature before inclusion in protocols or publications.

Product Description and Formulation Details

AK5 Mouse mAb (Aladdin catalog number Ab350173) is a mouse monoclonal antibody raised against the AK5 protein. The product is supplied in a PBS-only formulation, meaning it contains phosphate-buffered saline as the sole carrier without added preservatives such as sodium azide or stabilizers such as BSA, unless otherwise stated on the vial label or accompanying datasheet. Researchers should consult the product-specific datasheet for confirmed concentration, exact buffer composition, and lot-specific quality control data. The supplier reference for this product is absea #KC-30233.

Review flag: Exact antibody concentration, host/isotype subclass, immunogen sequence, and validated applications are not provided in the source material and must be confirmed from the official Aladdin product datasheet before experimental use.

Recommended Storage and Handling

Because AK5 Mouse mAb is formulated in PBS only without stated stabilizers, proper storage is essential to maintain antibody integrity and activity. General best-practice guidelines for monoclonal antibodies in PBS-only formulations include:

• Short-term storage (up to 1 month): Store at 4 °C. Avoid repeated freeze-thaw cycles.
• Long-term storage: Aliquot upon receipt and store at −20 °C or −80 °C. Single-use aliquots minimize freeze-thaw degradation.
• Avoid: Prolonged exposure to light, temperatures above 25 °C, and repeated freeze-thaw cycles.
• Carrier protein addition: If long-term stability is a concern and the application permits, addition of a carrier protein (e.g., 0.1% BSA) to working aliquots may be considered; consult the datasheet for guidance.

Review flag: Specific storage temperature recommendations and stated shelf-life must be confirmed from the official product datasheet, as they may differ from general guidelines.

Ordering, Availability and Quality Assurance

AK5 Mouse mAb is available from Aladdin Scientific under catalog number Ab350173. To place an order, contact your regional Aladdin representative or use the Aladdin Scientific online ordering portal. When ordering, please confirm:

• The required pack size and quantity.
• Lot-specific certificate of analysis (CoA) availability.
• Current pricing and promotional offers, which may vary by region.

Aladdin Scientific is committed to supplying high-quality research reagents. Each lot of AK5 Mouse mAb is expected to undergo quality control testing; details of QC methods (e.g., SDS-PAGE, ELISA, or functional assay) should be requested from technical support or accessed via the product datasheet.

Review flag: Specific QC methods, pass/fail criteria, and pack size options are not confirmed in the source material and should be verified with Aladdin Scientific customer support.

Frequently asked questions

What is the target of AK5 Mouse mAb and what species does it detect?

AK5 Mouse mAb targets adenylate kinase 5 (AK5), a phosphotransferase enzyme involved in nucleotide metabolism and energy homeostasis. The species reactivity (e.g., human, mouse, rat) is not confirmed in the available source material and must be verified from the official product datasheet for Ab350173.

What applications is AK5 Mouse mAb validated for?

The validated applications for Ab350173 are not specified in the available source material. Common applications for mouse monoclonal antibodies include Western blot (WB), immunohistochemistry (IHC), immunofluorescence (IF), immunoprecipitation (IP), and flow cytometry (FC). Please consult the official Aladdin Scientific product datasheet or contact technical support to confirm which applications have been validated for this specific antibody lot.

What is the formulation of AK5 Mouse mAb and how should it be stored?

AK5 Mouse mAb (Ab350173) is formulated in PBS only. It does not contain stated preservatives or carrier proteins, making proper aliquoting and storage critical. For short-term use, store at 4 °C; for long-term storage, aliquot and freeze at −20 °C or −80 °C and avoid repeated freeze-thaw cycles. Always confirm storage conditions on the product-specific datasheet.

How do I obtain a Certificate of Analysis (CoA) or Safety Data Sheet (SDS) for Ab350173?

Certificates of Analysis and Safety Data Sheets for Ab350173 can be requested from Aladdin Scientific customer support or downloaded from the Aladdin Scientific website using the product catalog number and lot number. If you cannot locate these documents online, please contact your regional Aladdin representative directly.

Can AK5 Mouse mAb be used for in vivo or clinical diagnostic applications?

AK5 Mouse mAb (Ab350173) is supplied as a research-grade reagent intended for in vitro research use only. It is not approved or validated for in vivo therapeutic use or clinical diagnostic applications. Researchers must comply with all applicable institutional and regulatory requirements when using this product.

References

1. Aladdin Scientific product page for AK5 Mouse mAb, catalog number Ab350173. Supplier reference: absea #KC-30233.
2. Dzeja PP, Terzic A. Adenylate kinase and AMP signaling networks: metabolite sensing, signal communication and body energy sensing. Int J Mol Sci. 2009;10(4):1729-1772. doi:10.3390/ijms10041729

Products are supplied for research and development use only. Not for use in humans, animals, diagnosis, or therapy.