Spectral chromosome karyotyping experiments
Throughout the history of clinical cytogenetics, G-banding has served as the "gold standard" for detecting total chromosomal abnormalities in clinical samples,
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3228 articles
Diagnosis of Fanconi anemia (congenital myelodysplasia)--dioxobutane (dibutyl epoxide) detection assay
Fanconi anemia (FA) is an autosomal recessive syndrome characterized by progressive bone marrow failure and an increased risk of malignancies, particularly acut
Fluorescence in situ hybridization of multicolor fibers
Source : Molecular Cytogenetics Techniques and Applications
Experimental molecular detection of uniparental diploids
Uniparental diploid (UPD) cells can have a normal cytogenetic karyotype but an imbalance in parental contributions. The diagnosis of uniparental diploidy involv
Meiosis mapping experiment
Currently, genetic mapping techniques can be used as a way to monitor the means of genomic manipulation, which needs to be realized through the use of molecular
Experiments on the effect of environment on gene expression in Drosophila
Many aspects of phenotype are influenced by the genetic composition of an organism and the environment in which it lives, so it can be said that phenotype is a
Fluorescent genotyping screening for tiny subtelomeric rearrangement assay
Our results strongly support the notion that microtelomeric rearrangements play a very important role in spontaneous mental retardation (approximately 12% in ou
Experimental application of fluorescence in situ hybridization in the preimplantation diagnosis of aneuploidy
Pre-implantation Genetic Diagnosis (PGD), as a major new method of preventing genetic disorders, avoids the need for prenatal diagnosis and the possibility of t
Experiments to identify chromatin-bound proteins from total cell extracts by immunoprecipitation methods
This experiment is both a simple and very sensitive method for determining whether a known protein in Saccharomyces cerevisiae binds to a known DNA sequence. So