Membrane agent inspection test
Membrane (Appendix I M of the 2010 edition of the Chinese Pharmacopoeia, Part II) refers to the membrane preparation made by processing the drug and suitable fi
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Experiments on the effect of neostigmine on the muscarinic action of succinylcholine and cylindrolysine
Myorelaxants are divided into two types: depolarizing and non-depolarizing. Succinylcholine is the representative drug of the depolarizing type of muscarinic dr
Determination of ED50 in mice by intraperitoneal injection of cartridge arrow toxins
A quantitative response is the intensity of the response in an individual and can be expressed as a continuous value, e.g., blood pressure, urine output, etc. T
Experimental effects of sodium phenobarbital and actinomycin D on cytochrome P-450 content in mouse liver
P-450 belongs to hemoglobin protein, and its reduced form combines with CO and shows an absorption peak at 450 nm. Therefore, the content of P-450 can be determ
Experimental measurement of pharmacokinetic parameters of sulfonamides
Sulfonamides can react with certain reagents to form colored substances, and their blood concentrations can be quantified by colorimetry. In acidic environments
Experimental prevention of barium chloride-induced arrhythmias by propranolol and quinidine
Barium chloride induces arrhythmias by increasing the inward Na+ current in Purkinje fibers and increasing the depolarization rate of the maximal diastolic pote
Experiments on the relationship between solubility and action of barium salts
Solubility-action relationship experiments with barium salts can be used to study the effect of the physicochemical properties of a drug on its action.
Experiments on the effect of different routes of administration on drug action
In pharmacology experiments, there are many factors affecting the experimental results, some of which can be controlled, while some are difficult to control. In
Experimental effects of efferent nervous system drugs on blood pressure and hemodynamics
Efferent nervous system drugs produce cardiovascular effects by acting on the corresponding receptors on cardiac and vascular smooth muscle, resulting in corres