IMR-1A - ≥97% , CAS No.331862-41-0

CAS: 331862-41-0 Cat. No.: I412257 분자식: C₁₃H₁₁NO₅S₂ 분자량: 325.36

GRADE & PURITY ≥97%

Synonyms

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Information

IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Targets

Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)

Specifications

동의어

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

사양 및 순도

≥97%

생화학 및 생리적 메커니즘

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥97%

제품 특성

• ALogP: 2.29
• hba_count: 4
• HBD 수: 1
• 회전 가능한 결합: 5

이름과 식별자

• Pubchem Sid: 488191798
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488191798
• 정식 스마일: COC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O
• IUPAC Name: 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
• InChIKey: DVBJNSKWHSGTDK-BJMVGYQFSA-N
• INCHI: 1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+
• 분자량: 325.36
• Reaxy-Rn: 29764446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln=

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 6 mg/mL (18.44 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO(mg/mL) 최대 용해도: 6
• DMSO(mM) 최대 용해도: 18.4411113843128
• 물(mg/mL) 최대 용해도: ＜1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 331862-41-0, the molecular formula is C13H11NO5S2, and the molecular weight is 325.36 g/mol. InChIKey DVBJNSKWHSGTDK-BJMVGYQFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.