Lampalizumab (anti-Complement Factor D) - 1차 항체, specific to CFD, >95%, Human IgG1, Antibody of complement factor D, Antibody of complement factor D

CAS: 1278466-20-8 Cat. No.: Ab175571

GRADE & PURITY Animal Free, Carrier Free, Recombinant, Validated, ExactAb™, Low Endotoxin, Azide Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

Application

Animal Model, ELISA, Flow Cytometry, Functional Assay

Host species

인간

Reactive species

원숭이, 인간, 토끼

Isotype

Human IgG1

Conjugation

Unconjugated

개요

Lampalizumab (anti-Complement Factor D) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab (anti-Complement Factor D) binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab (anti-Complement Factor D) can be used for age-related macular degeneration (AMD) research.

Specifications

Product Name

Lampalizumab (anti-Complement Factor D) - 1차 항체, specific to CFD, >95%, Human IgG1, Antibody of complement factor D

동의어

Adipsin antibody | Adipsin/complement factor D antibody | Adn antibody | C3 convertase activator antibody | CFAD_HUMAN antibody | CFD antibody | Complement factor D antibody | complement factor D preproprotein antibody | D component of complement antibody

사양 및 순도

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥95%(SDS-PAGE&SEC-HPLC), See COA

숙주 종

인간

특이성

CFD

변화

Unconjugated

등급

Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated

작업 유형

INHIBITOR

작동 메커니즘

Antibody of complement factor D

아이소타입

Human IgG1

라이트 체인 유형

kappa

SDS-PAGE

25.7 kDa (Light Chain) & 50.8 kDa (Heavy Chain), under reducing conditions; 180.0 kDa, under non-reducing conditions.

정화 방법

Protein A purified

순도

>95%

집중력

See COA

CAS

1278466-20-8

보관 및 배송

모양

Liquid

보관 조건

Store at -80°C,Avoid repeated freezing and thawing

배송

Dry ice packs + Cold packs

안정성 및 스토리지

Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

이미지

SEC: Lampalizumab (anti-Complement Factor D) (Ab175571)

Lampalizumab (anti-Complement Factor D) (Ab175571) - SEC
The purity of Lampalizumab (anti-Complement Factor D) (Ab175571) is more than 95% verified by HPLC.

관련 대상(인간)

CFD Tchem Complement factor D (0 Activities)

Discover Target: CFD

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

작용 메커니즘

자주 묻는 질문

What does Animal Free mean?

Animal Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

What does Carrier Free mean?

Carrier Free indicates that the material has been processed and tested for specialty industrial processing. Specifications focus on the impurities that affect performance in that application — for example, metal content for electronics, particle size for batteries, refractive index for optics, or moisture content for moisture-sensitive processes.

How should this product be stored?

Store at ?80 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1278466-20-8.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (Lampalizumab (anti-Complement Factor D)); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.