Miglitol - Moligand™, 10mM in DMSO , Inhibitor of alpha glucosidase;Inhibitor of maltase-glucoamylase, CAS No.72432-03-2, Inhibitor of alpha glucosidase;Inhibitor of maltase-glucoamylase

CAS: 72432-03-2 Cat. No.: M408218 분자식: C₈H₁₇NO₅ 분자량: 207.22 EC 번호: 276-661-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

BAY-M-1099 | (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Miglitol Miglitol (BAY-M-1099) is an oral anti-diabetic drug.
In vitro

In vivo

Cell Data

cell lines：COLO205, A375, WM2664, COLO829, HT716, SW620, H460, Calu-6, HCT116, SK-MEL2, SK-MEL3, Lovo, H1299, 1205Lu, and C8161 cells

Concentrations：

Incubation Time：

Powder Purity:≥100%

Specifications

동의어

BAY-M-1099 | (2R,3R,4R,5S)-1-(2-hydroxyethyl)-2-(hydroxymethyl)-3,4,5-piperidinetriol

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Miglitol (BAY-M-1099) is an oral anti-diabetic drug.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of alpha glucosidase;Inhibitor of maltase-glucoamylase

제품 특성

• ALogP: -2.6

이름과 식별자

• 이성체 SMILES: C1[C@@H]([C@H]([C@@H]([C@H](N1CCO)CO)O)O)O
• RTECS: TN4350170
• 분자량: 207.22
• Reaxy-Rn: 1448541
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1448541&ln=

관련 대상(인간)

GAA Tclin Lysosomal alpha-glucosidase (1 Activities)

Discover Target: GAA

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MGAM Tclin Maltase-glucoamylase, intestinal (1 Activities)

Discover Target: MGAM

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SI Tchem Sucrase-isomaltase, intestinal (0 Activities)

Discover Target: SI

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro
• 특정 회전[α]: -8°C
• 녹는점(°C): 146°C

참고 문헌

1. Wang Feifei, Wang Xinling, Wang Yu, Zhang Yin, Liu Tianxiang, Sun Jian.  (2025)  In situ formation of fluorescent non-conjugated polymer dots for α-glucosidase activity assay and inhibitor screening.  MICROCHIMICA ACTA,  192  (9): (1-10).  [PMID:40779177] [10.1007/s00604-025-07417-1]

2. Lei Li, Han Lu, Yuling Xue, Yannan He, Baohua Zhao, Lianzhong Ai, Shijie Wang.  (2025)  Natural selection of Lacticaseibacillus paracasei mutant: Weaken the post-acidification of fermented milk.  Food Bioscience,      [PMID:] [10.1016/j.fbio.2025.106014]

3. Yu Wang, Qilin Zhao, Qi Fang, Jian Sun, Yan Du, Haji Akber Aisa.  (2025)  A cascade nanoreactor based on metal azolate framework integrated natural enzyme for α-glucosidase activity assay and inhibitor screening.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40344727] [10.1016/j.jcis.2025.137764]