MitoPQ - Moligand™, ≥98% , CAS No.1821370-28-8

CAS: 1821370-28-8 Cat. No.: M275666 분자식: C₃₉H₄₆I₃N₂P 분자량: 954.48 PubChem CID: 129909777

GRADE & PURITY Moligand™, ≥98%

Synonyms

MitoParaquat

Storage

Store at 2-8°C,Protected from light,Argon charged,Desiccated

Shipped In

Wet ice

개요

MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study.

Specifications

동의어

MitoParaquat

사양 및 순도

Moligand™, ≥98%

생화학 및 생리적 메커니즘

Selective, mitochondria-targeted redox cycler. Selectively increases superoxide production within the mitochondrial matrix in vitro and in vivo . Comprises a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat.

보관 조건

Store at 2-8°C,Protected from light,Argon charged,Desiccated

배송

Wet ice

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등급

Moligand™

참고

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

순수함

≥98%

이름과 식별자

• Pubchem Sid: 528765637
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/528765637
• 정식 스마일: C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[I-].[I-].[I-]
• IUPAC Name: 10-[4-(1-methylpyridin-1-ium-4-yl)pyridin-1-ium-1-yl]decyl-triphenylphosphanium;triiodide
• InChIKey: AOZZGHKENAZYTD-UHFFFAOYSA-K
• INCHI: 1S/C39H46N2P.3HI/c1-40-30-25-35(26-31-40)36-27-32-41(33-28-36)29-17-6-4-2-3-5-7-18-34-42(37-19-11-8-12-20-37,38-21-13-9-14-22-38)39-23-15-10-16-24-39;;;/h8-16,19-28,30-33H,2-7,17-18,29,34H2,1H3;3*1H/q+3;;;/p-3
• 이성체 SMILES: C[N+]1=CC=C(C=C1)C2=CC=[N+](C=C2)CCCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5.[I-].[I-].[I-]
• PubChem CID: 129909777
• 분자량: 954.48

작용 메커니즘

화학 및 물리적 특성

• 용해성: Soluble in ethanol to 10 mM and in DMSO to 100 mM
• 감도: Moisture sensitive;Light sensitive
• 분자량: 954.500 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 15
• Exact Mass: 954.053 Da
• Monoisotopic Mass: 954.053 Da
• Topological Polar Surface Area: 7.800 Ų
• Heavy Atom Count: 45
• Formal Charge: 0
• Complexity: 646.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 4

XLogP3