Nimesulide - Moligand™, 10mM in DMSO , Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2, CAS No.51803-78-2, Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2

CAS: 51803-78-2 Cat. No.: N407977 분자식: C₁₃H₁₂N₂O₅S 분자량: 308.31 EC 번호: 257-431-4

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

N-​(4-​nitro-​2-​phenoxyphenyl)​-methanesulfonamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요

Information

Nimesulide is a relativelyCOX-2selective inhibitor withIC50of 26 μM.
In vitro

In vivo

Cell Data

cell lines：HepG2 cells

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

동의어

N-​(4-​nitro-​2-​phenoxyphenyl)​-methanesulfonamide

사양 및 순도

Moligand™, 10mM in DMSO

생화학 및 생리적 메커니즘

Nimesulide is a relatively COX-2 selective inhibitor with IC50 of 26 μM.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

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등급

Moligand™

작업 유형

INHIBITOR

작동 메커니즘

Inhibitor of B⁰AT1;Inhibitor of COX-1;Inhibitor of COX-2

이름과 식별자

이성체 SMILES

CS(=O)(=O)NC1=C(C=C(C=C1)[N+](=O)[O-])OC2=CC=CC=C2

WGK 독일

3

RTECS

PB0970000

분자량

308.31

Reaxy-Rn

2421175

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2421175&ln=

관련 대상(인간)

SLC6A19 Tchem Sodium-dependent neutral amino acid transporter B(0)AT1 (1 Activities)

Discover Target: SLC6A19

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS1 Tclin Prostaglandin G/H synthase 1 (1 Activities)

Discover Target: PTGS1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PTGS2 Tclin Prostaglandin G/H synthase 2 (8 Activities)

Discover Target: PTGS2

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 66 mg/mL (198.11 mM); Ethanol: -1 mg/mL
• 녹는점(°C): 150 °C