Name: SIS17 - 10mM in DMSO , CAS No.2374313-54-7
SKU: S422786
Availability: InStock

SIS17 - 10mM in DMSO , CAS No.2374313-54-7

CAS: 2374313-54-7 Cat. No.: S422786 분자식: C₂₁H₃₈N₂OS 분자량: 366.6 PubChem CID: 139035087

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SIS17 - 10mM in DMSO CAS No(2374313-54-7) by Aladdin Scientific

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주문 가능

GRADE & PURITY 10mM in DMSO

Synonyms

DTXSID701238689 | N'-Hexadecylthiophene-2-carbohydrazide | 2-Thiophenecarboxylic acid, 2-hexadecylhydrazide | BS-16273 | s6687 | D70091 | HY-128918 | MFCD32201127 | ZUD31354 | SIS 17; SIS17 | BDBM50565135 | EX-A6309 | SIS17 | SIS-17 | 2374313-54-7 | BCP31

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

개요 Specifications 제품 특성 이름과 식별자 Documentation Advanced Data Taxonomic Classification 3D 구조 관련 대상(인간) 관련 대상(비인간) 작용 메커니즘 인증서(CoA, COO, BSE/TSE 및 분석 차트) 화학 및 물리적 특성 솔루션 계산기 리뷰

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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

SIS17 SIS17 is a mammalian histone deacetylase 11 (HDAC 11) -specific inhibitor with IC50 of 0.83 μM. SIS17 inhibits the demyristoylation of HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

Targets

HDAC11 (Cell-free assay) 0.83 μM

Specifications

동의어

사양 및 순도

10mM in DMSO

생화학 및 생리적 메커니즘

SIS17 is a mammalian histone deacetylase 11 (HDAC 11)-specific inhibitor with IC50 of 0.83 μM. SIS17 inhibits the demyristoylation of HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

보관 조건

Store at -80°C

배송

Dry ice packs + Cold packs

이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.

제품 특성

ALogP	7.302
HBD 수	2
회전 가능한 결합	17

이름과 식별자

Pubchem Sid	528767100
정식 스마일	CCCCCCCCCCCCCCCCNNC(=O)C1=CC=CS1
IUPAC Name	N'-hexadecylthiophene-2-carbohydrazide
InChIKey	HSHXDCVZWHOWCS-UHFFFAOYSA-N
INCHI	1S/C21H38N2OS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18-22-23-21(24)20-17-16-19-25-20/h16-17,19,22H,2-15,18H2,1H3,(H,23,24)
이성체 SMILES	CCCCCCCCCCCCCCCCNNC(=O)C1=CC=CS1
PubChem CID	139035087
분자량	366.6

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - 분류 Thiophenes
    - Subclass Thiophene carboxylic acids and derivatives

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
분류	Thiophenes
Subclass	Thiophene carboxylic acids and derivatives
Intermediate Tree Nodes	Not available
Direct Parent	Thiophene carboxamides
Alternative Parents	Heteroaromatic compounds Thioenol ethers Sulfenyl compounds Carboxylic acids and derivatives Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Thiophene carboxamide - Heteroaromatic compound - Thioenolether - Sulfenyl compound - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
설명	This compound belongs to the class of organic compounds known as thiophene carboxamides. These are compounds containing a thiophene ring which bears a carboxamide.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D 구조

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리뷰

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DMSO(mg/mL) 최대 용해도	73
DMSO(mM) 최대 용해도	199.127114020731
물(mg/mL) 최대 용해도	＜1
분자량	366.600 g/mol
XLogP3	8.700
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	17
Exact Mass	366.27 Da
Monoisotopic Mass	366.27 Da
Topological Polar Surface Area	69.400 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	312.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1