SPA70 - Moligand™, ≥98% , CAS No.931314-31-7

CAS: 931314-31-7 Cat. No.: S650378 Molecular Weight: 415.51
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
4-((4-(tert-Butyl)phenyl)sulfonyl)-1-(2,5-dimethoxyphenyl)-5-methyl-1H-1,2,3-triazole | 1-(2,5-Dimethoxyphenyl)-4-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-5-methyl-1H-12,3-triazole | Specific PXR antagonist 70
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
S650378-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$99.90
25mg
S650378-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$227.90
100mg
S650378-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$509.90
500mg
S650378-500mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,089.90
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

SPA70 is a potent and selective antagonist of human pregnane X receptor (hPXR) , with an IC 50 of 540 nM ( K i =390 nM). SPA70 can enhance the chemosensitivity of cancer cells

Form:Solid

IC50& Target:IC50: 540 nM (hPXR)

Specifications

Synonyms
4-((4-(tert-Butyl)phenyl)sulfonyl)-1-(2, 5-dimethoxyphenyl)-5-methyl-1H-1, 2, 3-triazole | 1-(2, 5-Dimethoxyphenyl)-4-[[4-(1, 1-dimethylethyl)phenyl]sulfonyl]-5-methyl-1H-12, 3-triazole | Specific PXR antagonist 70
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
SPA70 is a potent and selective antagonist of human pregnane X receptor (hPXR) , with an IC 50 of 540 nM ( K i =390 nM). SPA70 can enhance the chemosensitivity of cancer cells.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Purity
≥98%
Names and Identifiers
Molecular Weight 415.51

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO : 40 mg/mL (96.27 mM; Need ultrasonic and warming)
Solution Calculators
Reviews

Customer Reviews

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