SU5204 - ≥98%, EZ tautomeric mixture , CAS No.186611-11-0

CAS: 186611-11-0 Cat. No.: S412303 분자식: C₁₇H₁₅NO₂ 분자량: 265.31 PubChem CID: 6509031

GRADE & PURITY ≥98%, EZ tautomeric mixture

Synonyms

2H-​Indol-​2-​one,3-​[(2-​ethoxyphenyl)​methylene]​-​1,​3-​dihydro-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

개요

Information

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM forFLK-1 (VEGFR-2)andHER2, respectively.

Targets

VEGFR-2 (Cell-free assay); HER2 (Cell-free assay) 4 μM; 51.5 μM

Specifications

동의어

2H-​Indol-​2-​one,3-​[(2-​ethoxyphenyl)​methylene]​-​1,​3-​dihydro-

사양 및 순도

≥98%, EZ tautomeric mixture

생화학 및 생리적 메커니즘

SU5204 is a tyrosine kinase inhibitor with IC50 of 4 μM and 51.5 μM for FLK-1 (VEGFR-2) and HER2, respectively.

보관 조건

Store at -20°C

배송

Ice chest + Ice pads

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순수함

≥98%

제품 특성

• ALogP: 3.063
• HBD 수: 1
• 회전 가능한 결합: 3

이름과 식별자

• Pubchem Sid: 504764270
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504764270
• 정식 스마일: CCOC1=CC=CC=C1C=C2C3=CC=CC=C3NC2=O
• IUPAC Name: (3Z)-3-[(2-ethoxyphenyl)methylidene]-1H-indol-2-one
• InChIKey: MEZFKCPUSMBMAY-KAMYIIQDSA-N
• INCHI: 1S/C17H15NO2/c1-2-20-16-10-6-3-7-12(16)11-14-13-8-4-5-9-15(13)18-17(14)19/h3-11H,2H2,1H3,(H,18,19)/b14-11-
• PubChem CID: 6509031
• 분자량: 265.31

화학 및 물리적 특성

• 용해성: Solubility (25°C) In vitro DMSO: 53 mg/mL (199.76 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO(mg/mL) 최대 용해도: 53
• DMSO(mM) 최대 용해도: 199.766311107761
• 물(mg/mL) 최대 용해도: ＜1

자주 묻는 질문

What is the purity of this product?

This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 186611-11-0, the molecular formula is C17H15NO2, and the molecular weight is 265.31 g/mol. InChIKey MEZFKCPUSMBMAY-KAMYIIQDSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.