tesamorelin, Agonist of GHRH receptor, CAS No.218949-48-5, Agonist of GHRH receptor

CAS: 218949-48-5 (free base) Cat. No.: rp175272 분자식: C₂₂₁H₃₆₆N₇₂O₆₇S · xC₂H₄O₂ 분자량: 5135.86 (free base)

GRADE & PURITY BioReagent, ≥98%, Peptide Assay ≥80%, Endotoxin＜10 EU/mg，Acetic acid＜10%

개요

Tesamorelin Acetate is a synthetic peptide analog of growth hormone-releasing hormone (GHRH), supplied as the acetate salt. It stimulates growth hormone secretion and increases insulin-like growth factor‑1 (IGF‑1) levels. It is widely used in mechanistic studies on endocrine regulation, metabolic physiology, obesity and lipid metabolism, as well as molecular and cellular assays including receptor binding and in vitro cell functional evaluation. This research-grade peptide is suitable for molecular biology and pharmacological research. It is for in vitro research use only and is not intended for human administration.

Sequence: trans-3-hexenoyl-Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu- Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu- Arg-Gly-Ala-Arg-Ala-Arg-Leu-NH₂

Specifications

Product Name

tesamorelin, Agonist of GHRH receptor, CAS No.218949-48-5

동의어

MQG94M5EEO | UNII-MQG94M5EEO | Tesamorelin | (3E)-hex-3-enoylsomatoliberin | TH 9507 | Tesamorelin [USAN:INN] | GTPL6959 | TH9507 | TH-9507 | DTXSID00583207 | Egrifta

등급

BioReagent

사양 및 순도

BioReagent, ≥98%, Peptide Assay ≥80%, Endotoxin＜10 EU/mg，Acetic acid＜10%

작업 유형

AGONIST

작동 메커니즘

Agonist of GHRH receptor

CAS

218949-48-5 (free base)

분자 유형

Peptide

Product Line

rp175272-5mg

보관 및 배송

집중력

Peptide Assay ≥80%, Endotoxin＜10 EU/mg，Acetic acid＜10%

보관 조건

Protected from light,Store at -20°C,Avoid repeated freezing and thawing

배송

Ice chest + Ice pads

안정성 및 스토리지

Store at- 20℃ long term (24 months).Store in the dark. Avoid freeze/thaw cycle.

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic Polymers
    • 분류 Polypeptides

• Kingdom: Organic compounds
• Superclass: Organic Polymers
• 분류: Polypeptides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Polypeptides
• Alternative Parents: Peptides Tyrosine and derivatives Arginine and derivatives Phenylalanine and derivatives Glutamic acid and derivatives Glutamine and derivatives Asparagine and derivatives Aspartic acid and derivatives Isoleucine and derivatives Leucine and derivatives Methionine and derivatives N-acyl-alpha amino acids and derivatives Valine and derivatives Tetracarboxylic acids and derivatives Serine and derivatives Alpha amino acid amides Alanine and derivatives Amphetamines and derivatives 1-hydroxy-2-unsubstituted benzenoids N-acyl amines Guanidines Amino acids Secondary alcohols Secondary carboxylic acid amides Primary carboxylic acid amides Sulfenyl compounds Dialkylthioethers Carboxylic acids Carboximidamides Hydrocarbon derivatives Carbonyl compounds Monoalkylamines Organic oxides Primary alcohols Imines
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Polypeptide - Alpha peptide - Tyrosine or derivatives - Phenylalanine or derivatives - Arginine or derivatives - Glutamine or derivatives - Glutamic acid or derivatives - Methionine or derivatives - Leucine or derivatives - Isoleucine or derivatives - Aspartic acid or derivatives - Asparagine or derivatives - Tetracarboxylic acid or derivatives - N-acyl-alpha amino acid or derivatives - Valine or derivatives - Alpha-amino acid amide - Serine or derivatives - Alanine or derivatives - Alpha-amino acid or derivatives - N-substituted-alpha-amino acid - Amphetamine or derivatives - Phenol - 1-hydroxy-2-unsubstituted benzenoid - Monocyclic benzene moiety - Fatty acyl - Fatty amide - Benzenoid - N-acyl-amine - Amino acid or derivatives - Amino acid - Carboxamide group - Guanidine - Secondary carboxylic acid amide - Primary carboxylic acid amide - Secondary alcohol - Thioether - Carboxylic acid derivative - Carboximidamide - Sulfenyl compound - Carboxylic acid - Dialkylthioether - Organic nitrogen compound - Organic oxide - Imine - Primary aliphatic amine - Organonitrogen compound - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Organosulfur compound - Organooxygen compound - Amine - Primary alcohol - Primary amine - Alcohol - Aromatic homomonocyclic compound
• 설명: This compound belongs to the class of organic compounds known as polypeptides. These are peptides containing ten or more amino acid residues.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

관련 대상(인간)

GHRHR Tclin Growth hormone-releasing hormone receptor (0 Activities)

Discover Target: GHRHR

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

유전 정보

• Alternate Names: MQG94M5EEO | UNII-MQG94M5EEO | Tesamorelin | (3E)-hex-3-enoylsomatoliberin | TH 9507 | Tesamorelin [USAN:INN] | GTPL6959 | TH9507 | TH-9507 | DTXSID00583207 | Egrifta
• Reference:
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