UltraPure dTTP (100mM) - BioReagent, DNase, RNase free, PCR Reagent, endotoxin tested, UltraBio™, Suitable for molecular biology, sterile, for DNA and RNA applications, ≥99%, 100mM , CAS No.18423-43-3

CAS: 18423-43-3 Cat. No.: U759852 Molecular Weight: 548.11 EC Number: 838-835-5

GRADE & PURITY Suitable for molecular biology, BioReagent, DNase, RNase free, PCR Reagent, Endotoxin tested, UltraBio™, Sterile, for DNA and RNA applications, ≥99%, 100mM

Synonyms

Deoxythymidine 5'-triphosphate | DTTP

Storage

Store at -20°C,Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

Overview

Physical appearance:Liquid
Storage buffer:Ultrapure water

Description of products:
dTTP (100mM, UltraPure) is a single-component of ultrapure dTTP, which is suitable for use in PCR, real-time PCR, RT-PCR, cDNA or DNA synthesis, primer extension reaction, DNA sequencing, DNA labeling, and other routine molecular biology reactions that require high-purity dNTP. The pH is titrated to 7.0-7.5 with NaOH solution. dNTP (Deoxy-ribonucleoside triphosphate) includes dATP (deoxyadenosine triphosphate), dCTP (deoxycytidine triphosphate), dGTP (deoxyguanosine triphosphate), dTTP (deoxythymidine triphosphate), and dUTP (deoxyuridine triphosphate). Among them, dATP, dCTP, dGTP and dTTP are indispensable in the PCR reaction as raw materials. DNA polymerase synthesizes a new DNA strand complementary to the DNA template strand by adding dNTPs that are complementary to the template in 5′ to 3′ direction, and thus the quality and concentration of dNTP are closely related to the amplification efficiency.
Precautions:
This product can be thawed at room temperature. Keep it on ice for use and store at -20℃ immediately after use. This product is for research use only, not for drug, clinical diagnosis, food, or other uses. For your safety and health, please wear a lab coat and disposable gloves during the operation.

Specifications

Synonyms

Deoxythymidine 5'-triphosphate | DTTP

Specifications & Purity

BioReagent, DNase, RNase free, PCR Reagent, endotoxin tested, UltraBio™, Suitable for molecular biology, sterile, for DNA and RNA applications, ≥99%, 100mM

Stability And Storage

Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Storage

Store at -20°C, Avoid repeated freezing and thawing

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

BioReagent, DNase, RNase free, Endotoxin tested, for DNA and RNA applications, PCR Reagent, Sterile, Suitable for molecular biology, UltraBio™

Purity

≥99%

Names and Identifiers

• PH: 7.0-7.5
• Canonical Smiles: CC1=CN(C(=O)NC1=O)C2CC(C(O2)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O.[Na+].[Na+].[Na+]
• IUPAC Name: trisodium;[[[(2R,3S,5R)-3-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate
• InChIKey: KNVJTOALWGZWAI-SPSULGLQSA-K
• INCHI: 1S/C10H17N2O14P3.3Na/c1-5-3-12(10(15)11-9(5)14)8-2-6(13)7(24-8)4-23-28(19,20)26-29(21,22)25-27(16,17)18;;;/h3,6-8,13H,2,4H2,1H3,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;;/q;3*+1/p-3/t6-,7+,8+;;;/m0.../s1
• Isomeric SMILES: CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O.[Na+].[Na+].[Na+]
• Molecular Weight: 548.11

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Pyrimidine nucleotides
      • Subclass Pyrimidine deoxyribonucleotides
        • Level5 Pyrimidine deoxyribonucleoside triphosphates
          • Level6 Pyrimidine 2'-deoxyribonucleoside triphosphates

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Pyrimidine nucleotides
• Subclass: Pyrimidine deoxyribonucleotides
• Intermediate Tree Nodes: Pyrimidine deoxyribonucleoside triphosphates
• Direct Parent: Pyrimidine 2'-deoxyribonucleoside triphosphates
• Alternative Parents: Pyrimidones Alkyl phosphates Hydropyrimidines Vinylogous amides Heteroaromatic compounds Oxolanes Lactams Ureas Secondary alcohols Oxacyclic compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic sodium salts Organic oxides Hydrocarbon derivatives Organic cations
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyrimidine 2'-deoxyribonucleoside triphosphate - Pyrimidone - Hydropyrimidine - Organic phosphoric acid derivative - Phosphoric acid ester - Pyrimidine - Alkyl phosphate - Oxolane - Heteroaromatic compound - Vinylogous amide - Lactam - Urea - Secondary alcohol - Organoheterocyclic compound - Azacycle - Organic alkali metal salt - Oxacycle - Organic nitrogen compound - Organic salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Alcohol - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic sodium salt - Organic cation - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleoside triphosphates. These are pyrimidine nucleotides with a triphosphate group linked to the ribose moiety lacking a hydroxyl group at position 2.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Melt Point(°C): 218 - 220°C

References

1. Yating Li, Jason Tan, Yanqin Tu, Jingnan Wu, Zaifang Zhang, Yifeng Wei, Xinan Jiao, Yan Zhou.  (2025)  Distinct Phage-Encoded Enzymes for Substitution of Deoxythymidine by Deoxyuridine in Phage Genomes.  Advanced Science,      [PMID:41001765] [10.1002/advs.202512937]

2. Liangliang Wang, Xiufeng Wu, Guanyu Chen, Yawen Chen, Lilan Xu, Jianmin Wang, Jinghua Chen.  (2023)  Dual amplified electrochemical sensing coupling of ternary hybridization-based exosomal microRNA recognition and perchlorate-assisted electrocatalytic cycle.  BIOSENSORS & BIOELECTRONICS,      [PMID:] [10.1016/j.bios.2023.115783]

3. Liang-Liang Wang, Wen-Qian Chen, Yu-Ru Wang, Lu-Peng Zeng, Ting-Ting Chen, Guan-Yu Chen, Jing-Hua Chen.  (2020)  Numerous long single-stranded DNAs produced by dual amplification reactions for electrochemical detection of exosomal microRNAs.  BIOSENSORS & BIOELECTRONICS,      [PMID:32927348] [10.1016/j.bios.2020.112555]

4. Ying Ding, Qingyan Jia, Yongmei Wen, Weimin Liu, Jiechao Ge, Jiasheng Wu, Hongyan Zhang, Pengfei Wang.  (2018)  New detection method for nucleoside triphosphates based on carbon dots: The distance-dependent singlet oxygen trapping.  ANALYTICA CHIMICA ACTA,      [PMID:30119732] [10.1016/j.aca.2018.05.024]