14,15-Leukotriene E4 - ≥97%, 100μg/ml in methanol , CAS No.1000852-57-2

CAS: 1000852-57-2 Cat. No.: L275445 Molecular Weight: 439.61 PubChem CID: 52921882

GRADE & PURITY ≥97%, 100μg/ml in methanol

Synonyms

(5Z,8Z,10E,12E,14R,15S)-14-[(2R)-2-Amino-2-carboxyethyl]sulfanyl-15-hydroxyicosa-5,8,10,12-tetraenoicacid | Eoxin-E4

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications

Synonyms

(5Z, 8Z, 10E, 12E, 14R, 15S)-14-[(2R)-2-Amino-2-carboxyethyl]sulfanyl-15-hydroxyicosa-5, 8, 10, 12-tetraenoicacid | Eoxin-E4

Specifications & Purity

≥97%, 100μg/ml in methanol

Biochemical and Physiological Mechanisms

Product of the 15-lipoxygenase (15-LOX) pathway. Shows anti-inflammatory activity. For in vivo and in vitro use.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -80°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥97%

Names and Identifiers

• Canonical Smiles: CCCCCC(C(C=CC=CC=CCC=CCCCC(=O)O)SCC(C(=O)O)N)O
• IUPAC Name: (5Z,8Z,10E,12E,14R,15S)-14-[(2R)-2-amino-2-carboxyethyl]sulfanyl-15-hydroxyicosa-5,8,10,12-tetraenoic acid
• InChIKey: JLJNENVYAVKECZ-HRXVJLLUSA-N
• INCHI: 1S/C23H37NO5S/c1-2-3-12-15-20(25)21(30-18-19(24)23(28)29)16-13-10-8-6-4-5-7-9-11-14-17-22(26)27/h4,6-10,13,16,19-21,25H,2-3,5,11-12,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29)/b6-4-,9-7-,10-8+,16-13+/t19-,20-,21+/m0/s1
• Isomeric SMILES: CCCCC[C@@H]([C@@H](/C=C/C=C/C=C\C/C=C\CCCC(=O)O)SC[C@@H](C(=O)O)N)O
• PubChem CID: 52921882
• Molecular Weight: 439.61

Chemical and Physical Properties

• Solubility: Supplied in methanol/ammonium acetate buffer, 70/30, pH 5.6 (50 µg/ml)
• Sensitivity: light sensitive