Explore cytokines for immune signaling studies, cell culture supplementation, differentiation workflows, and functional assays. Use this page to compare signaling proteins across research applications.
Cytokines
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- Recombinant Human GM-CSF ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥98%(SDS-PAGE&HPLC)In Stock Item #: rp146523View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P04141
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.01 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED50 for this effect is typically < 0.2ng/mL.
- Synonyms
- Human Granulocyte-Macrophage Colony Stimulating Factor | Colony stimulating factor 2 (granulocyte-macrophage) | Colon...
- Recombinant Human FGF basic/FGF2/bFGF ProteinCAS: 62031-54-3 Formula: Molecular Weight: 17kDLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE)In Stock Item #: rp155946View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P09038
- Expression system
- Oryza sativa
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.
- Synonyms
- basic fibroblast growth factor bFGF | Basic fibroblast growth factor | bFGF | FGF basic | FGF2 | FGF-2 | FGFBprostatr...
- Recombinant Human EGF ProteinCAS: 62253-63-8 EC Number: 810-845-4 PubChem CID: 16143379 Formula: C270H401N73O83S7 Molecular Weight: 6.5kDLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥98%(SDS-PAGE)In Stock Item #: rp155969View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P01133
- Expression system
- Pichia pastoris
- Protein Day
- No tag
- Endotoxin Concentration
- <1.0 EU/mg
- Bioactivity
- Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line. The ED₅₀ for this effect is typically <1 ng/mL.
- IUPAC Name
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- SMILES
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- InChIKey
- GVUGOAYIVIDWIO-UFWWTJHBSA-N
- InChI
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- Synonyms
- UNII-TZK30RF92W | Human EGF | MG 111 | CCRIS 6735 | Nepidermin [INN] | NEPIDERMIN | Human epidermal growth factor | T...
- Recombinant Mouse IL-6 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥96%(SDS-PAGE&HPLC)In Stock Item #: rp154236View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P08505
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using M-NFS-60 mouse B cell. The ED₅₀ for this effect is less than 0.4 ng/mL.
- Synonyms
- B-cell differentiation factor | B-cell stimulatory factor 2 | BSF2 | BSF-2 | CDF | CTL differentiation factor | HSF |...
- Recombinant Mouse IL-4 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)Out of Stock Item #: rp154228View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P07750
- Expression system
- HEK293
- Protein Day
- C-His
- Endotoxin Concentration
- <1.0 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.
- Synonyms
- B cell growth factor 1 | BCDF | B-cell stimulatory factor 1 | BCGF1 | BCGF-1 | binetrakin | BSF1 | BSF-1 | IL4 | IL-4...
- Recombinant Mouse TNF-alpha ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥97%(SDS-PAGE&HPLC)In Stock Item #: rp154759View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P06804
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.01 EU/μg
- Bioactivity
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.1 ng/mL.
- Synonyms
- Recombinant Murine Tumor Necrosis Factor alpha (rMuTNF-α) | APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, mo...
- Recombinant Human TRAIL ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)In Stock Item #: rp152616View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P50591
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- 1、Measured by its ability to induce apoptosis in Jurkat cells (Human T Lymphocyte Cells). The ED50 for this effect is typically <12ng/mL. 2、Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (A113142). The ED50 for this effect is 1.84 ng/mL.
- Synonyms
- Apo-2 ligand | Apo-2L | Protein TRAIL | TNF-related apoptosis-inducing ligand
- Recombinant Human TNF-alpha ProteinLiquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE) See COAIn Stock Item #: rp152506View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P01375
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D (Catalog # A113142). The ED₅₀ for this effect is typically <0.05 ng/mL.
- Synonyms
- APC1 protein | Cachectin | Cachetin | DIF | TNF | TNF, monocyte-derived | TNFA | TNF-A | TNFalpha | TNF-alpha | TNF-a...
- Recombinant Mouse IL-13 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥98%(SDS-PAGE&HPLC)In Stock Item #: rp154139View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Mouse
- Accession #
- P20109
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.01 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically <4ng/mL.
- Synonyms
- Allergic rhinitis | ALRH | BHR 1 | BHR1 | Bronchial hyperresponsiveness 1 (bronchial asthma) | IL 13 | IL-13 | Il13 |...
- Recombinant Human IGF-1 ProteinCAS: 67763-96-6Lyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE)In Stock Item #: rp147252View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P05019
- Expression system
- Pichia pastoris
- Protein Day
- No tag
- Endotoxin Concentration
- <0.2 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using MCF7 breast cancer cell line. The ED₅₀ for this effect is typically <4.6 ng/mL.
- Synonyms
- IGF-I | Mechano growth factor | MGF | Somatomedin-C
- Recombinant human FGF1 proteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. ≥95%(SDS-PAGE)In Stock Item #: rp145907View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P05230
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using BALB/3T3 mouse embryo fibroblasts cell line in the presence of heparin. The ED₅₀ for this effect is typically <0.5ng/mL.
- Synonyms
- Acidic fibroblast growth factor | aFGF | ECGF | Endothelial cell growth factor | FGF-1 | HBGF-1 | Heparin-binding gro...
- Recombinant Human KGF/FGF-7 ProteinLyophilized Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. High Performance ? High-performance grade with optimized purity and performance characteristics. Use for sensitive analyses where ordinary grades fall short. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE)In Stock Item #: rp148028View ProductPricing & Pack Sizes
Technical Identifiers
- Species
- Human
- Accession #
- P21781
- Expression system
- E. coli
- Protein Day
- No tag
- Endotoxin Concentration
- <0.1 EU/μg
- Bioactivity
- Measured in a cell proliferation assay using 4MBr‑5 rhesus monkey epithelial cell. The ED₅₀ for this effect is typically <1.38 ng/mL
- Synonyms
- FGF7 | FGF-7 | fibroblast growth factor 7 | HBGF-7 | HBGF7 | Heparin-binding growth factor 7 | keratinocyte growth fa...
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R&D Use Only Products supplied for research and development use
Frequently Asked Questions
How do I choose between recombinant and native Cytokines?
Recombinant proteins offer defined sequence, consistent quality, and tag options. Native proteins may have post-translational modifications closer to physiological state. Match source to your assay sensitivity.
What specifications matter for Cytokines?
Specific activity, purity (≥95% by SDS-PAGE typical), endotoxin level for cell-based assays, tag information, formulation buffer, and lot-to-lot consistency. Activity validation data is essential.
How should Cytokines be stored to maintain activity?
Most proteins ship on dry ice and require -80°C long-term storage, -20°C for working aliquots. Avoid freeze-thaw cycles. Some products require specific buffer conditions and stabilizers.
Are bioactivity-validated products available?
Yes. Cytokines include activity assays in the certificate of analysis. Specific activity is reported in U/mg with assay conditions specified, supporting quantitative experiments.