Antibody-Drug Conjugates (ADCs)

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  1. Azidobutyric acid NHS ester
    CAS: 943858-70-6 EC Number: 815-672-8 Formula: C8H10N4O4 Molecular Weight: 226.19
    Solid ≥95%
    In Stock Item #: A276210
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    Technical Identifiers
    IUPAC Name
    (2,5-dioxopyrrolidin-1-yl) 4-azidobutanoate
    SMILES
    C1CC(=O)N(C1=O)OC(=O)CCCN=[N+]=[N-]
    InChIKey
    YYULROINNKAMIB-UHFFFAOYSA-N
    InChI
    1S/C8H10N4O4/c9-11-10-5-1-2-8(15)16-12-6(13)3-4-7(12)14/h1-5H2
    Synonyms
    HY-126521 | F80654 | Butanoic acid, 4-aazido-a? 2,a?-adioxo-a?-apyrrolidinyl ester | LCZC461 | (2,5-dioxopyrrolidin-1...
  2. Gemtuzumab (anti-CD33), BINDING AGENT of Myeloid cell surface antigen CD33 binding agent
    CAS: 220578-59-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175859
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CD33
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG4SP; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG4SP
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    CD 33 antibody | CD33 antibody | CD33 antigen (gp67) antibody | CD33 antigen antibody | CD33 molecule antibody | CD33...
  3. Brentuximab vedotin (anti-CD30), Antibody of CD30
    CAS: 914088-09-8
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175479
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    TNFRSF8
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAE
    SMILES
    [Brentuximab vedotin]
    Synonyms
    CD 30 antibody | CD30 antibody | CD30 antigen antibody | CD30L receptor antibody | Cytokine receptor CD30 antibody | ...
  4. Enfortumab vedotin-ejfv (anti-Nectin-4), Antibody of nectin cell adhesion molecule 4
    CAS: 1346452-25-2
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175528
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    NECTIN4
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
    Species reactivity(Reacts with)
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAE
    SMILES
    [Enfortumab vedotin-ejfv]
    Synonyms
    DKFZp686K05193 antibody | EDSS1 antibody | Ig superfamily receptor LNIR antibody | Nectin 4 antibody | Nectin-4 antib...
  5. Glembatumumab vedotin (anti-GPNMB), BINDING AGENT of Transmembrane glycoprotein NMB binding agent
    CAS: 1182215-65-1
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175551
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    GPNMB
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG2SA; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
    Species reactivity(Reacts with)
    Human, Mouse
    Isotype
    Human IgG2SA
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAE
    Synonyms
    Glycoprotein (transmembrane) nmb antibody | Glycoprotein nmb antibody | Glycoprotein nmb like protein antibody | Gpnm...
  6. Polatuzumab vedotin-piiq (anti-CD79b), Antibody of CD79B
    CAS: 1313206-42-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175635
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CD79B
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAE
    SMILES
    [Polatuzumab vedotin]
    Synonyms
    AGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein...
  7. Tisotumab vedotin (anti-Tissue Factor), Antibody of coagulation factor III; tissue factor
    CAS: 1418731-10-8
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175681
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    F3
    Short Overview
    Purity≥90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAE)
    Species reactivity(Reacts with)
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAE
    Synonyms
    CD142 antibody | CD142 antigen antibody | Coagulation factor III (thromboplastin tissue factor) antibody | Coagulatio...
  8. Trastuzumab emtansine (anti-ERBB2), INHIBITOR of Receptor protein-tyrosine kinase erbB-2 inhibitor
    CAS: 1018448-65-1 PubChem CID: 163341910
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    Out of Stock Item #: Ab175686
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ERBB2
    Short Overview
    Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (SMCC-DM1)
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    SMCC-DM1
    SMILES
    C[C@@H]1[C@@H]2C[C@]([C@@H](/C=C\C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCSC5CC(=O)N(C5=O)CC6CCC(CC6)C(=O)show more
    Synonyms
    Verb b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog antibody | C er...
  9. Belantamab mafodotin (anti-BCMA), Antibody of B cell maturation antigen
    CAS: 2050232-20-5
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    Out of Stock Item #: Ab175467
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    TNFRSF17
    Short Overview
    Purity≥90% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0 EU/mg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Conjugated (MC-VC-PAB-MMAF)
    Species reactivity(Reacts with)
    Cynomolgus monkey, Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    MC-VC-PAB-MMAF
    SMILES
    [Belantamab mafodotin]
    Synonyms
    B cell maturation antigen antibody | B cell maturation factor antibody | B cell maturation protein antibody | B-cell ...
  10. Depatuxizumab mafodotin (anti-EGFR), BINDING AGENT of Epidermal growth factor receptor erbB1 binding agent
    CAS: 1585973-65-4
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. PBS Only ? PBS-only formulation — supplied in phosphate-buffered saline with no other additives. Use when you need a clean PBS buffer free of stabilizers/carriers. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175508
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    EGFR
    Short Overview
    Purity>95% ( SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (Mc-MMAF)
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Mc-MMAF
    Synonyms
    Avian erythroblastic leukemia viral (v erb b) oncogene homolog antibody | Cell growth inhibiting protein 40 antibody ...
  11. Lorvotuzumab mertansine (anti-NCAM1), BINDING AGENT of Neural cell adhesion molecule 1 binding agent
    CAS: 1008106-64-6
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    Out of Stock Item #: Ab175586
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    NCAM1
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (SMCC-DM1)
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    SMCC-DM1
    Synonyms
    antigen MSK39 identified by monoclonal antibody 5.1H11 antibody | antigen recognized by monoclonal antibody 5.1H11 an...
  12. Labetuzumab govitecan (anti-CEACAM5), Antibody of CD66e (CEACAM5)
    CAS: 1469876-18-3 PubChem CID: 91668184
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175570
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CEACAM5
    Short Overview
    Purity>90% (SDS-PAGE&SEC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Conjugated (CL2A-SN-38)
    Species reactivity(Reacts with)
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    CL2A-SN-38
    SMILES
    CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)OC(=O)OCC5=CC=C(C=C5)NC(=O)[C@H](CCCN)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN6C=C(N=N6)CNC(=O)C7CCC(CC7)CNshow more
    Synonyms
    Carcinoembryonic antigen antibody | Carcinoembryonic antigen-related cell adhesion molecule 5 antibody | CD66e antibo...
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