Radionuclide-Drug Conjugates (RDCs)

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  1. Diethylenetriaminepentaacetic acid dianhydride
    CAS: 23911-26-4 Formula: C14H19N3O8 Molecular Weight: 357.32
    In Stock Item #: D106364
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    Technical Identifiers
    IUPAC Name
    2-[bis[2-(2,6-dioxomorpholin-4-yl)ethyl]amino]acetic acid
    SMILES
    C1C(=O)OC(=O)CN1CCN(CCN2CC(=O)OC(=O)C2)CC(=O)O
    InChIKey
    RAZLJUXJEOEYAM-UHFFFAOYSA-N
    InChI
    1S/C14H19N3O8/c18-10(19)5-15(1-3-16-6-11(20)24-12(21)7-16)2-4-17-8-13(22)25-14(23)9-17/h1-9H2,(H,18,19)
    Synonyms
    NSC-125674 | NSC379317 | NSC-379317 | Uric acid, >=99%, crystalline | Glycine, N,N-bis(2-(2,6-dioxo-4-morpholinyl)eth...
  2. Trastuzumab (anti-ERBB2)
    CAS: 180288-69-1 EC Number: 695-702-2 Formula: C6470H10012N1726O2013S42 Molecular Weight: 145531.50
    Liquid ≥95% ~21mg/ml(in buffer,pH6.0)
    In Stock Item #: T305227
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ERBB2
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    IUPAC Name
    2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES
    C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey
    FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI
    1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
    Synonyms
    8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
  3. Tri-tert-butyl 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetate
    CAS: 137076-54-1 EC Number: 635-059-7 PubChem CID: 11606627 Formula: C28H52N4O8 Molecular Weight: 572.74
    Solid ≥97%
    In Stock Item #: T162093
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    IUPAC Name
    2-[4,7,10-tris[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetic acid
    SMILES
    CC(C)(C)OC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)O
    InChIKey
    RVUXZXMKYMSWOM-UHFFFAOYSA-N
    InChI
    1S/C28H52N4O8/c1-26(2,3)38-23(35)19-30-12-10-29(18-22(33)34)11-13-31(20-24(36)39-27(4,5)6)15-17-32(16-14-30)21-25(37)40-28(7,8)9/h10-21H2,1-9H3,(H,33,show more
    Synonyms
    2-(4,7,10-TRIS(2-TERT-BUTOXY-2-OXOETHYL)-1,4,7,10-TETRAAZACYCLODODECAN-1-YL)ACETIC ACID | Tri-tert-Bu-DOTA | FT-07280...
  4. 2,2',2''-(1,4,7-Triazonane-1,4,7-triyl)triacetic Acid
    CAS: 56491-86-2 EC Number: 878-923-0 PubChem CID: 124326 Formula: C12H21N3O6 Molecular Weight: 303.32
    Solid ≥98%(HPLC)
    In Stock Item #: T405110
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    Technical Identifiers
    IUPAC Name
    2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid
    SMILES
    C1CN(CCN(CCN1CC(=O)O)CC(=O)O)CC(=O)O
    InChIKey
    JHALWMSZGCVVEM-UHFFFAOYSA-N
    InChI
    1S/C12H21N3O6/c16-10(17)7-13-1-2-14(8-11(18)19)5-6-15(4-3-13)9-12(20)21/h1-9H2,(H,16,17)(H,18,19)(H,20,21)
    Synonyms
    A902686 | HY-134418 | MFCD00137938 | 1,4,7-Triazacyclononane-N,N',N''-triacetic acid | N,N',N''-Tris(carboxymethyl)-1...
  5. 2,2',2''-(1,4,7-Triazonane-1,4,7-triyl)triacetic Acid
    CAS: 56491-86-2 PubChem CID: 124326 Formula: C12H21N3O6 Molecular Weight: 303.32
    10mM in DMSO
    In Stock Item #: T424781
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    Technical Identifiers
    IUPAC Name
    2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid
    SMILES
    C1CN(CCN(CCN1CC(=O)O)CC(=O)O)CC(=O)O
    InChIKey
    JHALWMSZGCVVEM-UHFFFAOYSA-N
    InChI
    1S/C12H21N3O6/c16-10(17)7-13-1-2-14(8-11(18)19)5-6-15(4-3-13)9-12(20)21/h1-9H2,(H,16,17)(H,18,19)(H,20,21)
    Synonyms
    NOTA|56491-86-2|2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid|1,4,7-Triazacyclononane-N,N',N''-triacetic...
  6. Cetuximab (anti-EGFR)
    CAS: 205923-56-4 Formula: Molecular Weight: 145543.35
    Liquid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95% Protein concentration:5mg/ml
    In Stock Item #: C302740
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    Technical Identifiers
    Associated targets
    EGFR
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
  7. Rituximab (anti-CD20), BINDING AGENT of B-lymphocyte antigen CD20 binding agent
    CAS: 174722-31-7 EC Number: 695-706-4 PubChem CID: 168009840
    Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. ≥97% See COA
    In Stock Item #: R412001
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    MS4A1
    Short Overview
    Immunology & Inflammation related Antibodies
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    SMILES
    CC=CC1=CC(=CC=C1)N(CC2=CC=C(C=C2)C3=CC4=C(C=C3)N=CC4)C(=O)C5CCCCC5.CC=CC1=CC(=CC=C1)N(CC2=CC=C(C=C2)C3=CC4=C(C=C3)N=C(O4)C)C(=O)C5CCCCC5.COC(=O)C=CC1=show more
    Synonyms
    IDEC-C2B8
  8. Trastuzumab (anti-HER2), Antibody of erb-b2 receptor tyrosine kinase 2
    CAS: 180288-69-1 Formula: C6470H10012N1726O2013S42 Molecular Weight: 145531.50
    Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: T411999
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    ERBB2
    Short Overview
    Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level<1.0EU/mg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Species reactivity(Reacts with)
    Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    IUPAC Name
    2,8-diamino-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
    SMILES
    C(C1C(C(C(O1)N2C3=C(C(=O)NC(=N3)N)N=C2N)O)O)O
    InChIKey
    FNXPTCITVCRFRK-UMMCILCDSA-N
    InChI
    1S/C10H14N6O5/c11-9-14-6-3(7(20)15-9)13-10(12)16(6)8-5(19)4(18)2(1-17)21-8/h2,4-5,8,17-19H,1H2,(H2,12,13)(H3,11,14,15,20)/t2-,4-,5-,8-/m1/s1
    Synonyms
    8-Aminoguanosine, >=98% (HPLC) | SHO2CA1BRO | Guanosine, 8-amino- | SCHEMBL483333 | 2,8-diamino-9-[(2R,3R,4S,5R)-3,4-...
  9. Cetuximab (anti-EGFR), Antibody of epidermal growth factor receptor
    CAS: 205923-56-4 Formula: Molecular Weight: 145543.35
    Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: C411992
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    EGFR
    Short Overview
    Purity≥95% (SDS-PAGE&SEC-HPLC); Endotoxin Level< 0.01EU/μg; Human IgG1; CHO; ELISA, Flow Cytometry, Functional assay, Animal Model; Unconjugated
    Species reactivity(Reacts with)
    Cynomolgus monkey, Human, Mouse
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    C225 | Recombinant Cetuximab Antibody | Cetuximab (anti-EGFR) | Cetuximab (C225) | Anti-ERBB1 / EGFR / HER1 Reference...
  10. Lintuzumab (anti-CD33), Antibody of CD33
    CAS: 166089-32-3
    Liquid Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥95%(SDS-PAGE&SEC-HPLC) See COA
    In Stock Item #: Ab175581
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    Pricing & Pack Sizes
    Technical Identifiers
    Associated targets
    CD33
    Short Overview
    Purity>95% (SDS-PAGE&SEC); Endotoxin Level < 0.01EU/μg; Human IgG1; CHO; ELISA, FACS, Functional assay, Animal Model; Unconjugated
    Species reactivity(Reacts with)
    Human
    Isotype
    Human IgG1
    Host species
    Human
    Conjugation
    Unconjugated
    Synonyms
    CD 33 antibody | CD33 antibody | CD33 antigen (gp67) antibody | CD33 antigen antibody | CD33 molecule antibody | CD33...
  11. 2-Aminoethyl-mono-amide-DOTA-tris(tBu ester)
    CAS: 173308-19-5 PubChem CID: 22660448 Formula: C30H58N6O7 Molecular Weight: 614.82
    Solid ≥98%
    Out of Stock Item #: A646441
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    Technical Identifiers
    IUPAC Name
    tert-butyl 2-[4-[2-(2-aminoethylamino)-2-oxoethyl]-7,10-bis[2-[(2-methylpropan-2-yl)oxy]-2-oxoethyl]-1,4,7,10-tetrazacyclododec-1-yl]acetate
    SMILES
    CC(C)(C)OC(=O)CN1CCN(CCN(CCN(CC1)CC(=O)OC(C)(C)C)CC(=O)OC(C)(C)C)CC(=O)NCCN
    InChIKey
    TVUPYCMMXREXSS-UHFFFAOYSA-N
    InChI
    1S/C30H58N6O7/c1-28(2,3)41-25(38)21-34-14-12-33(20-24(37)32-11-10-31)13-15-35(22-26(39)42-29(4,5)6)17-19-36(18-16-34)23-27(40)43-30(7,8)9/h10-23,31H2,show more
    Synonyms
    Tri-tert-butyl 2,2',2''-(10-(2-((2-aminoethyl)amino)-2-oxoethyl)-1,4,7,10-tetraazacyclododecane-1,4,7-triyl)triacetat...
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