16α-Hydroxy Progesterone - ≥98% , CAS No.438-07-3

CAS: 438-07-3 Cat. No.: H336075 Summenformel: C₂₁H₃₀O₃ Molekulargewicht: 330.46 EG-Nummer: 881-156-4

GRADE & PURITY Moligand™, ≥98%

Synonyms

16a-hydroxyprogesterone | Pregn-4-ene-3, 16.alpha.-hydroxy- | Pregn-4-ene-3,20-dione, 16.alpha.-hydroxy- | Pregn-4-ene-3, 16-hydroxy-, (16.alpha.)- | NSC 523249 | SMR000457347 | UNII-Y7JT9A46EO | 16alpha-hydroxyprogesterone1 | DTXSID001017030 | (8S,9S,10R

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Übersicht

16α-Hydroxy Progesterone a hydroxylated metabolite of Progesterone that binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.

Specifications

Synonyme

16a-hydroxyprogesterone | Pregn-4-ene-3, 16.alpha.-hydroxy- | Pregn-4-ene-3,20-dione, 16.alpha.-hydroxy- | Pregn-4-ene-3, 16-hydroxy-, (16.alpha.)- | NSC 523249 | SMR000457347 | UNII-Y7JT9A46EO | 16alpha-hydroxyprogesterone1 | DTXSID001017030 | (8S,9S,10R

Spezifikationen & Reinheit

Moligand™, ≥98%

Storage

Store at -20°C,Argon charged

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Note

Moligand™

Reinheit

≥98%

Namen und Kennungen

• Pubchem Sid: 504758065
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504758065
• Kanonisches Lächeln: CC(=O)C1C(CC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
• IUPAC Name: (8S,9S,10R,13S,14S,16R,17R)-17-acetyl-16-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
• InChIKey: LOVNYFVWYTXDRE-RMWFXKKMSA-N
• INCHI: 1S/C21H30O3/c1-12(22)19-18(24)11-17-15-5-4-13-10-14(23)6-8-20(13,2)16(15)7-9-21(17,19)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17+,18-,19+,20+,21+/m1/s1
• Isomere SMILES: CC(=O)[C@H]1[C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
• Molekulargewicht: 330.46
• Reaxy-Rn: 2062092
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2062092&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Klasse Steroids and steroid derivatives
      • Subclass Pregnane steroids

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Klasse: Steroids and steroid derivatives
• Subclass: Pregnane steroids
• Intermediate Tree Nodes: Not available
• Direct Parent: Gluco/mineralocorticoids, progestogins and derivatives
• Alternative Parents: 20-oxosteroids 3-oxo delta-4-steroids 16-alpha-hydroxysteroids Delta-4-steroids Cyclohexenones Secondary alcohols Cyclic alcohols and derivatives Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic homopolycyclic compounds
• Substituents: Progestogin-skeleton - 20-oxosteroid - 3-oxo-delta-4-steroid - 3-oxosteroid - 16-hydroxysteroid - 16-alpha-hydroxysteroid - Hydroxysteroid - Oxosteroid - Delta-4-steroid - Cyclohexenone - Cyclic alcohol - Ketone - Secondary alcohol - Cyclic ketone - Hydrocarbon derivative - Organic oxygen compound - Carbonyl group - Alcohol - Organic oxide - Organooxygen compound - Aliphatic homopolycyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as gluco/mineralocorticoids, progestogins and derivatives. These are steroids with a structure based on a hydroxylated prostane moiety.
• External Descriptors: C21 steroids (gluco/mineralocorticoids, progestogins) and derivatives

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Chloroform (Slightly), Methanol (Slightly, Heated, Sonicated)
• Empfindlichkeit: Moisture sensitive
• Schmelzpunkt (°C): >212°C (dec.)
• Molekulargewicht: 330.500 g/mol
• XLogP3: 3.300
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 330.219 Da
• Monoisotopic Mass: 330.219 Da
• Topological Polar Surface Area: 54.400 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 621.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 7
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referenzen

1. Ma Jinglin, Zhuang Yan, Guan Huiting, Zhang Zhenjun, Zhu Ning, Han Changze, Wang Yonggang, Chen Jixiang.  (2026)  Functional characterization of steroid hydroxylation by cytochrome P450 enzymes from Rhodococcus erythropolis KB1.  Microbial Cell Factories,      [PMID:41612368] [10.1186/s12934-026-02940-z]