2,2'-Dithiodipyridine - ≥98% , CAS No.2127-03-9

CAS: 2127-03-9 Cat. No.: D100574 Summenformel: C₁₀H₈N₂S₂ Molekulargewicht: 220.31 Beilstein Registry Number: 154629 EG-Nummer: 218-343-1

QUALITÄT & REINHEIT ≥98%

Synonyms

Aldrithiol 2 | dipyridyl disulfide | HY-Y1666 | 2,2 inverted exclamation marka-Dipyridyl disulfide | 2,2'-Dipyridinyl disulfide | EN300-172822 | 2-Pyridin-2-yldisulfanylpyridine | L6X912UPBU | 2PDS | 2,2'-Dithiobispyridine | 2,2'-dithiobis-pyridine | Bis(

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Übersicht

Aldrithiol™-2 is a nucleocapsid zinc finger targeting compound and can abrogate the infectivity of human immunodeficiency virus type-1 virions. It is a thiol reagent.

Spezifikationen

Synonyme

Aldrithiol 2 | dipyridyl disulfide | HY-Y1666 | 2,2 inverted exclamation marka-Dipyridyl disulfide | 2,2'-Dipyridinyl disulfide | EN300-172822 | 2-Pyridin-2-yldisulfanylpyridine | L6X912UPBU | 2PDS | 2,2'-Dithiobispyridine | 2,2'-dithiobis-pyridine | Bis(

Spezifikationen & Reinheit

≥98%

Anmeldung

Aldrithiol™-2 was used in the synthesis of adenosine-5′-phosphoimidazolide. It was employed with PPh3 as a condensing agent in the amidation of carboxylic acid enantiomers for HPLC separation. Thiol reagent.Employed with PPh3 as a condensing agent in the

Storage

Store at 2-8°C,Argon charged

Verschickt in

Wet ice

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Reinheit

≥98%

Namen und Kennungen

Pubchem Sid

508807539

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/508807539

Kanonisches Lächeln

C1=CC=NC(=C1)SSC2=CC=CC=N2

IUPAC Name

2-(pyridin-2-yldisulfanyl)pyridine

InChIKey

HAXFWIACAGNFHA-UHFFFAOYSA-N

INCHI

1S/C10H8N2S2/c1-3-7-11-9(5-1)13-14-10-6-2-4-8-12-10/h1-8H

Isomere SMILES

C1=CC=NC(=C1)SSC2=CC=CC=N2

WGK Deutschland

3

UN-Nummer

3335

Molekulargewicht

220.31

Beilstein

154629

Reaxy-Rn

154629

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=154629&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Klasse Pyridines and derivatives

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Klasse: Pyridines and derivatives
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyridines and derivatives
• Alternative Parents: Heteroaromatic compounds Organic disulfides Sulfenyl compounds Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Pyridine - Heteroaromatic compound - Organic disulfide - Azacycle - Sulfenyl compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organosulfur compound - Organonitrogen compound - Aromatic heteromonocyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as pyridines and derivatives. These are compounds containing a pyridine ring, which is a six-member aromatic heterocycle which consists of one nitrogen atom and five carbon atoms.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

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EHMT2 Tchem Histone-lysine N-methyltransferase EHMT2 (1 Activities)

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Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D receptor (26531 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PLK1 Tchem Serine/threonine-protein kinase PLK1 (28605 Activities)

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HepG2 (196354 Activities)

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FEN1 Tchem Flap endonuclease 1 (12055 Activities)

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POLI Tchem DNA polymerase iota (116820 Activities)

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G6PD Tchem Glucose-6-phosphate 1-dehydrogenase (778 Activities)

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KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT1 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 5 (407 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)

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GMNN Tbio Geminin (128009 Activities)

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APOBEC3A Tchem Probable DNA dC->dU-editing enzyme APOBEC-3A (890 Activities)

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CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)

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APOBEC3G Tchem DNA dC->dU-editing enzyme APOBEC-3G (12481 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RGS4 Tchem Regulator of G-protein signaling 4 (13867 Activities)

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)

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GLS Tchem Glutaminase kidney isoform, mitochondrial (16997 Activities)

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CGA Tbio Glycoprotein hormones alpha chain (29278 Activities)

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WRN Tbio Werner syndrome ATP-dependent helicase (8824 Activities)

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Human immunodeficiency virus 1 (70413 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

ddn Putative uncharacterized protein (49 Activities)

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Large T antigen (1457 Activities)

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G6PD-6PGL Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase (1761 Activities)

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MSRA Mitochondrial peptide methionine sulfoxide reductase (338 Activities)

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vpr Aberrant vpr protein (14595 Activities)

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Wirkungsmechanismen

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in water, benzene, tetrahydrofuran, dichloromethane, acetonitrile and dimethyformamide.
• Empfindlichkeit: Air Sensitive
• Flammpunkt (°F): 210 °C
• Flammpunkt (°C): 210 °C
• Schmelzpunkt (°C): 56-60°C
• Molekulargewicht: 220.300 g/mol
• XLogP3: 2.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 220.013 Da
• Monoisotopic Mass: 220.013 Da
• Topological Polar Surface Area: 76.400 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 148.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1