2-Bromo-2-methylpropionic acid - ≥98% , CAS No.2052-01-9

CAS: 2052-01-9 Cat. No.: B106968 Summenformel: C₄H₇BrO₂ Molekulargewicht: 167 Beilstein Registry Number: 1745543 EG-Nummer: 218-139-2

GRADE & PURITY ≥98%

Synonyms

AKOS015841143 | 2-BROMO-2-METHYL-D3-PROPIONIC-3,3,3-D3 ACID | Alpha-bromoisobutyricacid | bromoisobutyric acid | bromo-isobutyric acid | InChI=1/C4H7BrO2/c1-4(2,5)3(6)7/h1-2H3,(H,6,7) | DTXSID8062151 | NSC41213 | NSC-41213 | 2-Bromo-2-methylpropionic acid

Storage

Protected from light,Room temperature

Shipped In

Normal

Übersicht

The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

Specifications

Synonyme

AKOS015841143 | 2-BROMO-2-METHYL-D3-PROPIONIC-3,3,3-D3 ACID | Alpha-bromoisobutyricacid | bromoisobutyric acid | bromo-isobutyric acid | InChI=1/C4H7BrO2/c1-4(2,5)3(6)7/h1-2H3,(H,6,7) | DTXSID8062151 | NSC41213 | NSC-41213 | 2-Bromo-2-methylpropionic acid

Spezifikationen & Reinheit

≥98%

Storage

Protected from light,Room temperature

Verschickt in

Normal

Reinheit

≥98%

Namen und Kennungen

• Pubchem Sid: 508808372
• Kanonisches Lächeln: CC(C)(C(=O)O)Br
• IUPAC Name: 2-bromo-2-methylpropanoic acid
• InChIKey: XXSPGBOGLXKMDU-UHFFFAOYSA-N
• INCHI: 1S/C4H7BrO2/c1-4(2,5)3(6)7/h1-2H3,(H,6,7)
• Isomere SMILES: CC(C)(C(=O)O)Br
• WGK Deutschland: 3
• UN-Nummer: 3261
• Molekulargewicht: 167
• Beilstein: 1745543
• Reaxy-Rn: 1745543
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1745543&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Klasse Carboxylic acids and derivatives
      • Subclass Alpha-halocarboxylic acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Klasse: Carboxylic acids and derivatives
• Subclass: Alpha-halocarboxylic acids and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Alpha-halocarboxylic acids
• Alternative Parents: Monocarboxylic acids and derivatives Carboxylic acids Organobromides Organic oxides Hydrocarbon derivatives Carbonyl compounds Alkyl bromides
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-halocarboxylic acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organobromide - Organohalogen compound - Carbonyl group - Alkyl halide - Alkyl bromide - Aliphatic acyclic compound
• Beschreibung: This compound belongs to the class of organic compounds known as alpha-halocarboxylic acids. These are carboxylic acids containing a halogen atom bonded to the alpha carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemische und physikalische Eigenschaften

• Löslichkeit: Soluble in alcohol and ether. Slightly soluble in water.
• Empfindlichkeit: Light sensitive.
• Flammpunkt (°F): 230°F
• Flammpunkt (°C): >110 °C
• Siedepunkt (°C): 198-200°C
• Schmelzpunkt (°C): 46°C
• Molekulargewicht: 167.000 g/mol
• XLogP3: 1.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 165.963 Da
• Monoisotopic Mass: 165.963 Da
• Topological Polar Surface Area: 37.300 Ų
• Heavy Atom Count: 7
• Formal Charge: 0
• Complexity: 87.700
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referenzen

1. Jia Liu, Zhengchun Cai, Yongxin Ji.  (2023)  Synthesis of bio-based modified amphoteric acrylate epoxy emulsion surface sizing agent via RAFT polymerization.  JOURNAL OF APPLIED POLYMER SCIENCE,  140  (39): (e54462).  [PMID:] [10.1002/app.54462]

2. Feng Han, Zhengdong Tu, Zhuang Zhu, Dachuan Liu, Qingchen Meng, Qifan Yu, Ying Wang, Jianquan Chen, Tao Liu, Fengxuan Han, Bin Li.  (2023)  Targeting Endogenous Reactive Oxygen Species Removal and Regulating Regenerative Microenvironment at Annulus Fibrosus Defects Promote Tissue Repair.  ACS Nano,      [PMID:37022700] [10.1021/acsnano.3c00093]

3. Kedong Liu, Yun Chen, Zhaoqi Yang, Jian Jin.  (2023)  zwitterionic Pluronic analog-coated PLGA nanoparticles for oral insulin delivery.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:36870645] [10.1016/j.ijbiomac.2023.123870]

4. Jing Hu, Xin Liu, Qun Gao, Chunfa Ouyang, Kangsheng Zheng, Xiaoqian Shan.  (2023)  Thermosensitive PNIPAM-Based Hydrogel Crosslinked by Composite Nanoparticles as Rapid Wound-Healing Dressings.  BIOMACROMOLECULES,      [PMID:36857757] [10.1021/acs.biomac.2c01380]

5. Yan Li, Hongrui Zhu, Junbo Duan, Youshen Wu, Daocheng Wu.  (2022)  Laser-induced photoexcited audible sound effect based on reticular 2-bromo-2-methylpropionic acid modified Fe3O4 nanoparticle aggregates.  Nanoscale,  14  (45): (16787-16796).  [PMID:36342384] [10.1039/D2NR04895G]

6. Ting Cheng, Wenming Yang, Wenjie Hao, Yue Yang, Xiang Li, Taohua Wei, Lulu Tang.  (2021)  A colorimetry-impedance dual-mode ceruloplasmin detection strategy based on dendritic mesoporous silicon nanoparticles with CeO2 encapsulation inside and horseradish peroxidase enrichment outside.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2021.131312]

7. Ting Su, Furong Cheng, Yuji Pu, Jun Cao, Shuibin Lin, Guizhi Zhu, Bin He.  (2021)  Polymeric micelles amplify tumor oxidative stresses through combining PDT and glutathione depletion for synergistic cancer chemotherapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:37304676] [10.1016/j.cej.2021.128561]

8. Xiao Wang, Pengxiang Yu, Kangmin Zhang, Mingyuan Wu, Qingyun Wu, Jiuyi Liu, Jianjun Yang, Jianan Zhang.  (2020)  Robust and durable polymer grafted cotton fabrics for sequential oil/water separation and heavy metal ions removal based on surface initiated ATRP.  POLYMER,      [PMID:] [10.1016/j.polymer.2020.123002]

9. Xiao Wang, Pengxiang Yu, Kangmin Zhang, Mingyuan Wu, Qingyun Wu, Jiuyi Liu, Jianjun Yang, Jianan Zhang.  (2019)  Superhydrophobic/Superoleophilic Cotton for Efficient Oil–Water Separation Based on the Combined Octadecanoyl Chain Bonding and Polymer Grafting via Surface-Initiated ATRP.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.9b00585]

10. Xue Yang, Yan Sun, Yang Xiang, Fengtao Qiu, Guoqi Fu.  (2019)  Controlled synthesis of PEGylated surface protein-imprinted nanoparticles.  ANALYST,  144  (18): (5439-5448).  [PMID:31410417] [10.1039/C9AN01221D]

11. Yi-Xin Zhang, Hao Hu, Yao Chen, Hai-Lin Cong, You-Qing Shen, Bing Yu.  (2019)  Preparation and Evaluation of Zwitterionic Polymer Coated Capillary Columns for Analysis of Proteins by Capillary Electrophoresis.  INTEGRATED FERROELECTRICS,      [PMID:] [10.1080/10584587.2019.1592600]

12. Haibin Wu, Fangyuan Li, Shuaifei Wang, Jingxiong Lu, Jinquan Li, Yang Du, Xiaolian Sun, Xiaoyuan Chen, Jianqing Gao, Daishun Ling.  (2017)  Ceria nanocrystals decorated mesoporous silica nanoparticle based ROS-scavenging tissue adhesive for highly efficient regenerative wound healing.  BIOMATERIALS,      [PMID:29078200] [10.1016/j.biomaterials.2017.10.018]

13. Cao Qi, He Naipu, Wang Yue, Lu Zhenwu.  (2017)  Self-assembled nanostructures from amphiphilic globular protein–polymer hybrids.  POLYMER BULLETIN,  75  (6): (2627-2639).  [PMID:] [10.1007/s00289-017-2176-y]

14. Yongyong Li, Xue Lei, Haiqing Dong, Tianbin Ren.  (2014)  Sheddable, degradable, cationic micelles enabling drug and gene delivery.  RSC Advances,  4  (16): (8165-8176).  [PMID:] [10.1039/C3RA46756B]

15. Yunqing Zhu, Lin Liu, Jianzhong Du.  (2012)  Probing into Homopolymer Self-Assembly: How Does Hydrogen Bonding Influence Morphology?.  MACROMOLECULES,      [PMID:] [10.1021/ma302176a]

16. Xuan Bai, Wenan Peng, Ying Tang, Ziming Wang, Jingmei Guo, Fangfang Song, Hongye Yang, Cui Huang.  (2024)  An NIR-propelled janus nanomotor with enhanced ROS-scavenging, immunomodulating and biofilm-eradicating capacity for periodontitis treatment.  Bioactive Materials,      [PMID:39149593] [10.1016/j.bioactmat.2024.07.014]

17. Minghao Wang, Haomin Yu, Jiawei Jiang, Wencong Xu, Guofeng Xu, Si Wu.  (2024)  Cis-trans isomerism-driven thermal and phase transitions in oleic and elaidic acids and their derived polymers.  POLYMER,      [PMID:] [10.1016/j.polymer.2024.127954]

18. Chuan Cao, Fangzhi Mou, Manyi Yang, Shuming Zhang, Di Zhang, Luolin Li, Tong Lan, Dunyi Xiao, Wei Luo, Huiru Ma, Jianguo Guan.  (2024)  Harnessing Disparities in Magnetic Microswarms: From Construction to Collaborative Tasks.  Advanced Science,  11  (30): (2401711).  [PMID:38868929] [10.1002/advs.202401711]

19. Ruiyu Fu, Xiaoqin Hai, Qingxin Lu, Hongbo Li, Jiaxiao Niu, Yanhui Zhang, Tingze Ren, Xiaoli Guo, Xin Di.  (2024)  Molecularly imprinted polymer gel with superior recognition and adsorption capacity for amphenicol antibiotics in food matrices.  FOOD CHEMISTRY,      [PMID:39303467] [10.1016/j.foodchem.2024.141255]

20. Chenchen Wang, Xiaolei Song, Peng Li, Shihao Sun, Juan Su, Songqin Liu, Wei Wei.  (2024)  Multifunctional Nanocarrier for Synergistic Treatment of Alzheimer’s Disease by Inhibiting β-Amyloid Aggregation and Scavenging Reactive Oxygen Species.  ACS Applied Materials & Interfaces,      [PMID:38747495] [10.1021/acsami.4c02825]

21. Fang Hao, Zhu-Ying Yan, Zhenyu Wang, Xiu-Ping Yan.  (2024)  Persistent Luminescence Nanoplatform for Autofluorescence-Free Tracking of Submicrometer Plastic Particles in Plant.  ANALYTICAL CHEMISTRY,      [PMID:38875183] [10.1021/acs.analchem.4c01382]

22. Zhang Kangmin, Wang Miaomiao, Wu Mingyuan, Wu Qingyun, Liu Jiuyi, Yang Jianjun, Zhang Jianan.  (2019)  Fabrication of robust superhydrophobic filter paper for oil/water separation based on the combined octadecanoyl chain bonding and polymer grafting via surface-initiated ATRP.  CELLULOSE,  27  (1): (469-480).  [PMID:] [10.1007/s10570-019-02810-5]

23. Wang Xia, Zhang Yawen, Zhao Liying, Wang Dazhong, Yang Huaixia, Kong Jinming.  (2020)  Polysaccharide-enhanced ARGET ATRP signal amplification for ultrasensitive fluorescent detection of lung cancer CYFRA 21-1 DNA.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  412  (11): (2413-2421).  [PMID:32047944] [10.1007/s00216-020-02394-1]

24. Li Bohan, Fu Qingyu, Lu Yan, Chen Cheng, Zhao Yingshuai, Zhao Yuanfeng, Cao Minghui, Zhou Wei, Fan Xiaoliang, Jiang Xiaoyu, Zhao Peng, Zheng Yijun.  (2025)  3D hydrogel platform with macromolecular actuators for precisely controlled mechanical forces on cancer cell migration.  Nature Communications,  16  (1): (1-15).  [PMID:40413192] [10.1038/s41467-025-60062-3]

25. Li Weiming, Jia Yuzhen, Chen Kunyilan, Li Huifang, Yang Huaixia, Guo Liang, Miao Mingsan.  (2025)  Target-driven ratiometric electrochemical aptasensor based on polymerization and AuNP signal amplification for acetamiprid residue determination.  MICROCHIMICA ACTA,  192  (7): (1-12).  [PMID:40549055] [10.1007/s00604-025-07217-7]

26. Chengyu Li, Wentian Zhang, Huilin Li, Lichao Xia, Shangwei Zhang, Fangang Meng, Shanshan Zhao.  (2025)  Amphiphilic molecular brush-grafted nanofiltration membranes via stable initiator immobilization: A dual defense strategy against complex fouling in leachate.  JOURNAL OF MEMBRANE SCIENCE,      [PMID:] [10.1016/j.memsci.2025.124832]