2-Chloroadenosine - Moligand™, 10 mM in DMSO , CAS No.146-77-0

CAS: 146-77-0 Cat. No.: C1500268 Molecular Weight: 301.69 Beilstein Registry Number: 43957 EC Number: 205-678-3
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1ml
C1500268-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2-Chloroadenosine, a stable adenosine analogue, protects against long term development of ischaemic cell loss in the rat hippocampus. 2-Chloroadenosine is an apparent competitive inhibitor of uridine influx (apparent K i =33 μM) and high-affinity nitrobenzylthioinosine binding (apparent K i =0.18 mM). 2-Chloroadenosine is a transported permeant for the nucleoside transporter in human erythrocytes .

Specifications

Specifications & Purity
Moligand™, 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Names and Identifiers
Isomeric SMILES C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)Cl)N
WGK Germany 3
RTECS AU7357550
Molecular Weight 301.69
Beilstein 43957
Reaxy-Rn 23207945
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23207945&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
Specific Rotation[α][α]D -50° (C=0.1,H2O)
Melt Point(°C)162 °C
Citations of This Product
References
1. Guangrong Sun, Pei Guo, Han Yeong Kaw, Meijiao Zhou, Wei Wang.  (2023)  Uncovering an Emerging Group of Halogenated Nucleobase-Derived Disinfection Byproducts in Drinking Water: Prioritization of the Highly Cytotoxic 2-Chloroadenine.  ENVIRONMENTAL SCIENCE & TECHNOLOGY,      [PMID:37232460] [10.1021/acs.est.3c01484]
2. Guangrong Sun, Pei Guo, Rong Liu, Han Yeong Kaw, Wei Wang.  (2025)  Fragmentation pattern-based nontargeted screening strategy uncovered novel halogenated nucleotides in drinking water.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:40037189] [10.1016/j.jhazmat.2025.137797]
3. Jiaying Long, Yicong Zhang, Mengxing Zhang, Zhenkang Diao, Taotian Zhang, Hanming Zhang, Qing Lin, Tao Gong, Xun Sun, Zhirong Zhang, Shiqi Huang, Ling Zhang.  (2025)  Delivery of NK cells in an injectable dynamic hydrogel effectively remodels tumor microenvironment and inhibits post-surgery tumor recurrence.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163507]
Solution Calculators
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