Determine the necessary mass, volume, or concentration for preparing a solution.
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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 19 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
application:
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides which after phosphorylation to dCTP is used to synthesis DNA via various DNA polymerases or reverse transcriptases. 2′-Deoxycytidine (deoxyC) is the substrate for deoxycytidine deaminase (EC 3.5.4.14) which converts it into 2′-deoxyuridine. 2′-Deoxycytidine is phosphorylated to the nucleotide dCMP by the enzyme deoxycytidine kinase (DCK).
product description:
2′-Deoxycytidine (deoxyC) is one of the deoxynucleosides containing cytosine as the nucleobase. It is found in the blood, feces, and urine.
application:
2′-Deoxycytidine has been used:
as a substrate for Trypanosoma brucei cytidine deaminase (TbCDA) to measure its activity
as a standard in the isolation and quantification of metabolite levels in murine tumor interstitial fluid by liquid chromatography-mass spectrometry (LC–MS)
to study the role of autophagy in response to oncogenes and DNA replication stress
| Pubchem Sid | 504752485 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504752485 |
| Kanonisches Lächeln | C1C(C(OC1N2C=CC(=NC2=O)N)CO)O |
| IUPAC Name | 4-amino-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one |
| InChIKey | CKTSBUTUHBMZGZ-SHYZEUOFSA-N |
| INCHI | 1S/C9H13N3O4/c10-7-1-2-12(9(15)11-7)8-3-5(14)6(4-13)16-8/h1-2,5-6,8,13-14H,3-4H2,(H2,10,11,15)/t5-,6+,8+/m0/s1 |
| Isomere SMILES | C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO)O |
| WGK Deutschland | 3 |
| RTECS | HA3800000 |
| Alternative CAS-Nummer | 652157-52-3 |
| Molekulargewicht | 227.22 |
| Beilstein | 87567 |
| Reaxy-Rn | 14609546 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14609546&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Nucleosides, nucleotides, and analogues |
| Klasse | Pyrimidine nucleosides |
| Subclass | Pyrimidine 2'-deoxyribonucleosides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Pyrimidine 2'-deoxyribonucleosides |
| Alternative Parents | Pyrimidones Aminopyrimidines and derivatives Imidolactams Hydropyrimidines Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Oxacyclic compounds Azacyclic compounds Primary amines Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteromonocyclic compounds |
| Substituents | Pyrimidine 2'-deoxyribonucleoside - Aminopyrimidine - Pyrimidone - Hydropyrimidine - Pyrimidine - Imidolactam - Heteroaromatic compound - Tetrahydrofuran - Secondary alcohol - Azacycle - Oxacycle - Organoheterocyclic compound - Alcohol - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Primary amine - Primary alcohol - Organooxygen compound - Organonitrogen compound - Organic oxygen compound - Organic nitrogen compound - Amine - Aromatic heteromonocyclic compound |
| Beschreibung | This compound belongs to the class of organic compounds known as pyrimidine 2'-deoxyribonucleosides. These are compounds consisting of a pyrimidine linked to a ribose which lacks a hydroxyl group at position 2. |
| External Descriptors | Deoxyribonucleosides |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Datum | Artikel |
|---|---|---|---|
| Certificate of Analysis | Sep 03, 2026 | D104773 | |
| Certificate of Analysis | Sep 03, 2026 | D104773 | |
| Certificate of Analysis | Sep 03, 2026 | D104773 | |
| Certificate of Analysis | Jun 01, 2026 | D104773 | |
| Certificate of Analysis | Jun 01, 2026 | D104773 | |
| Certificate of Analysis | Jun 01, 2026 | D104773 | |
| Certificate of Analysis | Jun 01, 2026 | D104773 | |
| Certificate of Analysis | Jun 01, 2026 | D104773 | |
| Certificate of Analysis | Dec 10, 2025 | D104773 | |
| Certificate of Analysis | Jun 18, 2025 | D104773 | |
| Certificate of Analysis | Jun 18, 2025 | D104773 | |
| Certificate of Analysis | Mar 11, 2025 | D104773 | |
| Certificate of Analysis | Nov 02, 2022 | D104773 | |
| Certificate of Analysis | Nov 02, 2022 | D104773 | |
| Certificate of Analysis | Nov 02, 2022 | D104773 | |
| Certificate of Analysis | Nov 02, 2022 | D104773 | |
| Certificate of Analysis | Jan 18, 2022 | D104773 | |
| Certificate of Analysis | Jul 31, 2021 | D104773 |
| Löslichkeit | Soluble in water, DMSO. |
|---|---|
| Spezifische Drehung [α] | 59 ° (C=1, H2O) |
| Schmelzpunkt (°C) | 209-211°C |
| Molekulargewicht | 227.220 g/mol |
| XLogP3 | -1.800 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 227.091 Da |
| Monoisotopic Mass | 227.091 Da |
| Topological Polar Surface Area | 108.000 Ų |
| Heavy Atom Count | 16 |
| Formal Charge | 0 |
| Complexity | 355.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 3 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Wenqing Wang, Hao Li, Meiyao Li, Huiling Lu, Jianming Pan. (2023) Layer-by-layer assembled magnetic molecularly imprinted nanoparticles for highly specific separation of adenosine 5′-monophosphate: Relations between adsorption properties and imprinted layers. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2023.125346] |
| 2. Meiyao Li, Pan Wang, Shunshun Luo, Yu Wu, Xiaohua Tian, Jianming Pan. (2023) Construction of anti-biofouling imprinted sorbents based on anisotropic polydopamine nanotubes for fast and selective capture of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2023.123384] |
| 3. Pan Wang, Mengdei Zhou, Zhuangxin Wei, Lu Liu, Tao Cheng, Xiaohua Tian, Jianming Pan. (2023) Preparation of bowl-shaped polydopamine surface imprinted polymer composite adsorbent for specific separation of 2′-deoxyadenosine. CHINESE JOURNAL OF CHEMICAL ENGINEERING, [PMID:] [10.1016/j.cjche.2023.01.009] |
| 4. Zhuangxin Wei, Pan Wang, Xiaohua Tian, Wei sun, Jianming Pan. (2022) Imprinted polymer beads featuring both predefined multiple-point interaction and accessible binding sites for precise recognition of 2′-deoxyadenosine. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2022.122048] |
| 5. Chang Xiangwei, Zhang Zhenyu, Yan Hui, Su Shulan, Wei Dandan, Guo Sheng, Shang Erxin, Sun Xiaodong, Gui Shuangying, Duan Jinao. (2021) Discovery of Quality Markers of Nucleobases, Nucleosides, Nucleotides and Amino Acids for Chrysanthemi Flos From Different Geographical Origins Using UPLC–MS/MS Combined With Multivariate Statistical Analysis. Frontiers in Chemistry, [PMID:34422760] [10.3389/fchem.2021.689254] |
| 6. Jia Ding, Fei Liu, Chunling Qi, Yunlei Zhou, Huanshun Yin, Shiyun Ai. (2021) Enhanced photoactivity of perovskite Bi4NbO8Cl/PTC-NH2 heterojunction and its application for photoelectrochemical sensing of DNA hydroxymethylation. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2021.130211] |
| 7. Yang Hongmei, Su Rui, Wishnok John S., Liu Ning, Chen Changbao, Liu Shuying, Tannenbaum Steven R.. (2019) Magnetic silica nanoparticles for use in matrix-assisted laser desorption ionization mass spectrometry of labile biomolecules such as oligosaccharides, amino acids, peptides and nucleosides. MICROCHIMICA ACTA, 186 (2): (1-8). [PMID:30637518] [10.1007/s00604-018-3208-5] |
| 8. Yuanyuan Xu, Yue Yang, Aifang Xue, Hao Chen, Shengqing Li. (2018) In situ precipitation of hydrous titanium dioxide for dispersive micro solid-phase extraction of nucleosides and their separation. NEW JOURNAL OF CHEMISTRY, 42 (7): (4909-4914). [PMID:] [10.1039/C7NJ04590E] |
| 9. Li-li Zhang, Yong-liang Bai, Shu-lan Shu, Da-wei Qian, Zhen Ou-yang, Li Liu, Jin-ao Duan. (2014) Simultaneous quantitation of nucleosides, nucleobases, amino acids, and alkaloids in mulberry leaf by ultra high performance liquid chromatography with triple quadrupole tandem mass spectrometry. JOURNAL OF SEPARATION SCIENCE, 37 (11): (1265-1275). [PMID:24616434] [10.1002/jssc.201301267] |
| 10. Sheng Guo, Jin-ao Duan, Dawei Qian, Hanqing Wang, Yuping Tang, Yefei Qian, Dawei Wu, Shulan Su, Erxin Shang. (2013) Hydrophilic interaction ultra-high performance liquid chromatography coupled with triple quadrupole mass spectrometry for determination of nucleotides, nucleosides and nucleobases in Ziziphus plants. JOURNAL OF CHROMATOGRAPHY A, [PMID:23800804] [10.1016/j.chroma.2013.05.074] |
| 11. Hongmei Yang, Debin Wan, Fengrui Song, Zhiqiang Liu, Shuying Liu. (2013) Argon Direct Analysis in Real Time Mass Spectrometry in Conjunction with Makeup Solvents: A Method for Analysis of Labile Compounds. ANALYTICAL CHEMISTRY, [PMID:23252884] [10.1021/ac3026543] |
| 12. Pan Wang, Tao Cheng, Zhuangxin Wei, Lu Liu, Yue Wang, Xiaohua Tian, Jianming Pan. (2024) Bioinspired Surface Engineering with Dual Covalent Receptors Incorporated via Precise Post-Imprinting Modification to Enhance the Specific Identification of Adenosine 5′-Monophosphate. Engineering, [PMID:] [10.1016/j.eng.2024.11.015] |
| 13. Yamin Liu, Xunjiang Wang, Jiaojiao Wei, Kangning Fu, Yilin Chen, Linnan Li, Zhengtao Wang, Li Yang. (2024) Comprehensive Profiling of Amino Acids and Derivatives in Biological Samples: A Robust UHPLC-MS/MS Method for Investigating Acute Lung Injury. JOURNAL OF CHROMATOGRAPHY A, [PMID:38537486] [10.1016/j.chroma.2024.464816] |
| 14. Pan Wang, Jiahui Chen, Lu Liu, Xiaohua Tian, Jianming Pan. (2024) Construction of dual receptors imprinted polymers by precise control of sequential assembly efficiency in confined sites to enhance specific separation of adenosine 5′-monophosphate. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.126353] |
| 15. Tong Ren, Zhen Feng, Fang Jiang, Xingtong Liu, Tingting Chen, Yanli Guo, Lei Tian, Xiao-Feng Kang, Fujun Yao. (2024) Nanopore detection of guanine derivatives based on vacancy G-quadruplex DNA. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2024.112366] |
| 16. Tao Cheng, Yaotao Cai, Yifan Su, JinTao Xu, Xiaohua Tian, Pan Wang, Jianming Pan. (2024) Selective separation of adenosine 5′-monophosphate by Dual-Receptor Post-Imprinted modified polymers using hydrophilic MOF nanosheets as substrates with active functional groups. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.128071] |
| 17. Zhuangxin Wei, Pan Wang, Jiangnan Wang, Jianming Pan. (2024) Synergy of Post-Crosslinked imprinting strategy and silanol chemistry for the anisotropic construction of molecularly imprinted polymers onto Halloysite nanotubes. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.150704] |
| 18. Ruixue Meng, Yue Xiong, Meijiao Zhou, Mine Du, Lizhong Zhu, Wei Wang. (2026) Identification of Halophenol-Deoxyguanosine Adducts in SV-HUC-1 Cells Exposed to Halobenzoquinones via the Neutral Loss and Information-Dependent Acquisition Strategy. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:41543259] [10.1021/acs.est.5c12092] |
| 19. Zhuangxin Wei, Tao Wang, Pan Wang, Jianming Pan. (2026) Synergistic integration of oil-mediated adhesion and post-crosslinking imprinting technology for surface imprinted polymers to precision separation of 2′-deoxyadenosine. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2026.173960] |