3-AP-Me , CAS No.1184391-57-8

CAS: 1184391-57-8 Cat. No.: A1416536 Summenformel: C₉H₁₃N₅S Molekulargewicht: 223.3 EG-Nummer: 808-469-0 PubChem CID: 44235406

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Übersicht

3-AP-Me is a dimethyl derivative of the nucleotide reductase inhibitor 3-AP (SML0568). 3-AP-Me can activate the endoplasmic reticulum (ER) stress pathway by promoting the phosphorylation of eIF2α and increasing the gene expression of transcription factors ATF4 and ATF6 , leading to cell apoptosis. Additionally, 3-AP-Me can activate the stress kinases c-Jun N-terminal kinase ( JNK ) and p38 mitogen-activated protein kinases. 3-AP-Me also leads to the upregulation of the spliced mRNA variant XBP1, can be used in cancer research.

Specifications

Storage

Store at -20°C

Verschickt in

Ice chest + Ice pads

Dieses Produkt erfordert Kühlkettenversand. Grundversand und andere Economy-Optionen sind nicht verfügbar.

Aktionsart

ACTIVATOR

Namen und Kennungen

• Kanonisches Lächeln: CN(C)C(=S)NN=CC1=C(C=CC=N1)N
• IUPAC Name: 3-[(E)-(3-aminopyridin-2-yl)methylideneamino]-1,1-dimethylthiourea
• InChIKey: DQVSEUUIXQTWRB-WUXMJOGZSA-N
• INCHI: 1S/C9H13N5S/c1-14(2)9(15)13-12-6-8-7(10)4-3-5-11-8/h3-6H,10H2,1-2H3,(H,13,15)/b12-6+
• Isomere SMILES: CN(C)C(=S)N/N=C/C1=C(C=CC=N1)N
• WGK Deutschland: 3
• PubChem CID: 44235406
• Molekulargewicht: 223.3

Häufig gestellte Fragen

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1184391-57-8, the molecular formula is C9H13N5S, and the molecular weight is 223.3 g/mol. InChIKey DQVSEUUIXQTWRB-WUXMJOGZSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.